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How transmission occurs news

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Vaginal and rectal bacteria may have a big influence on HIV transmission and microbicide efficacy

A number of presentations at the 2016 HIV Research for Prevention Conference (HIVR4P) in Chicago looked at the influence vaginal bacteria have on HIV susceptibility, and one

Published
20 October 2016
By
Gus Cairns
Most contraceptives not linked to HIV infection, but Depo-Provera may raise risk

Birth control pills and some types of injectable and implanted contraceptives were not associated with an increased risk of HIV acquisition in an updated meta-analysis that included

Published
17 August 2016
By
Liz Highleyman
HIV/AIDS: Filarial worm infections double the risk of infection

Since the start of the HIV epidemic, there have been speculations as to why HIV and the immunodeficiency syndrome it causes have spread so much more in Africa than in other countries around the world. Scientists have now, for the first time, confirmed one reason for this: in a cohort study conducted in Tanzania, they discovered that an infection with the filarial nematode Wuchereria bancrofti increases the risk of HIV infection by two to three fold.

Published
16 August 2016
From
Eurekalert Inf Dis
Early-capture HIV study allows for characterization of acute infection period

Acute HIV infection (AHI) contributes significantly to HIV transmission and may be important for intervention strategies seeking to reduce incidence and achieve a functional cure. In a study by the U.S. Military HIV Research Program (MHRP), Walter Reed Army Institute of Research, published in The New England Journal of Medicine, scientists enrolled and intensively followed a cohort of high-risk individuals, tracking their HIV status and characterizing the disease through the acute stages of HIV infection.

Published
19 May 2016
From
EurekAlert!
HIV-infected vaginal cells do not transmit HIV if plasma viral load is undetectable, researchers find

A group of researchers have cleared up an important question about HIV transmission, in experiments on mice. Although HIV-infected CD4 cells persist in the vagina even on

Published
15 February 2016
By
Gus Cairns
Have sex workers revealed a connection between semen exposure and HIV resistance?

In a new study, scientists at The Wistar Institute have found that continued semen exposure in these sex workers sustains changes in the cervical and vaginal microenvironment in a way that may actually increase HIV-1 resistance. This information may lead the way to better preventative strategies that block the transmission of the virus and improved designs for future HIV vaccine studies that can monitor the described changes when recruiting sex workers into vaccine trials.

Published
09 December 2015
From
Eurekalert Inf Dis
Meet the HIV-negative men who won't have sex with HIV-positive men

FS surveyed 3,140 gay men and found 44% of HIV-negative men that would not have sex with an openly HIV-positive man. So we decided to reach out to these men and ask them directly, why?

Published
02 December 2015
From
FS
Superhero Vaginal Bacteria Species Traps HIV, Could Be a Natural Condom Someday

The benevolent powers of the vaginal microbiome are even greater than we thought. In addition to aiding fertilization and protecting fetuses during pregnancy, healthy vaginal mucus that’s full of good bacteria can trap and immobilize HIV particles. The study examined the cervicovaginal mucus, or CVM, of 31 women and tested its ability to immobilize HIV particles. CVM samples that contained higher concentrations of D-lactic acid, which only bacteria can produce, did far better than others. The D-lactic acid wasn’t itself a barrier to HIV, but an indicator of something else going on that made certain types of CVM better at trapping the virus than others. That something was Lactobacillus crispatus, a species of bacteria that could change the way we think about HIV prevention.

Published
08 October 2015
From
Slate
Infection with multiple HIV-1 variants leads to poorer clinical outcomes

HIV-1 infection with multiple founder variants points to poorer clinical outcomes than infection with a single variant, according to a paper published today in Nature Medicine. In the study researchers analyzed large sample sets from two important HIV vaccine efficacy trials -- the Step HIV vaccine clinical trial (HVTN 502) and RV144, the landmark vaccine clinical trial conducted in Thailand -- to evaluate whether genetic characteristics of the founder viral populations could influence markers of clinical outcomes.

Published
01 September 2015
From
Eurekalert Inf Dis
The sexual and reproductive health issue you’ve probably never heard of….

Why is one of the most common gynaecological conditions in sub-Saharan Africa, schistosomiasis, misunderstood, under-researched and under-reported? It is a significant risk factor for HIV acquisition in women.

Published
06 July 2015
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.