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HIV 'superinfection' boosts immune response: Findings may provide insight into HIV-vaccine development

Women who have been infected by two different strains of HIV from two different sexual partners – a condition known as HIV superinfection – have more potent antibody responses that block the replication of the virus compared to women who’ve only been infected once.

Published
30 March 2012
From
Science Daily
Superinfection: second HIV infections happen as often as first ones

Two studies of people with HIV in Rakai, Uganda and Mombasa, Kenya presented at the 19th Conference on Retroviruses and Opportunistic Infections show that the rate at

Published
10 March 2012
By
Gus Cairns
Deeper view of HIV reveals impact of early mutations

Mutations in HIV that develop during the first few weeks of infection may play a critical role in undermining a successful early immune response, a finding that reveals the importance of vaccines targeting regions of the virus that are less likely to mutate.

Published
09 March 2012
From
Science Daily (press release)
A new patient zero? Researchers may have spotted animal-to-human immunodeficiency virus transfer

A group of scientists working in Ivory Coast may have discovered a case of infection of a human with a novel variety of an animal immunodeficiency virus,

Published
07 March 2012
By
Gus Cairns
Psoriasis Linked to Protection from HIV-1

Many psoriasis patients have the same gene variants as people who are not significantly affected by an HIV-1 infection.

Published
06 March 2012
From
Scientific American
Are HIV Non-Progressors Really Very Slow Progressors?

HIV positive people traditionally classified as long-term non-progressors or viral controllers may in fact progress slowly over time, according to research reported in the February 20, 2012, edition of the open-access journal PLoS ONE. These findings suggest that so-called non-progressors may in fact benefit from antiretroviral therapy and could provide clues to aid in development of immune-based therapies.

Published
27 February 2012
From
HIVandHepatitis.com
Immune cells use 'starvation tactics' on HIV

Scientists have shown how some cells in the body can repel attacks from HIV by starving the virus of the building blocks of life. Viruses cannot replicate on their own; they must hijack other other cells and turn them into virus production factories.

Published
12 February 2012
From
BBC News
Virus Related to HIV Found in One Quarter of Ape Hunters in Gabon

Nearly one quarter of humans bitten or scratched while hunting nonhuman primates in Gabon had evidence of simian foamy retrovirus (SFV), a virus closely related to HIV. The finding underlines the continuing risk of cross-species transmission of retroviruses.

Published
18 January 2012
From
International AIDS Society
Pathogenic Landscape of HIV

In perhaps the most comprehensive survey of the inner workings of HIV, an international team of scientists led by researchers at the University of California, San Francisco has mapped every apparent physical interaction the virus makes with components of the human cells it infects—work that may reveal new ways to design future HIV/AIDS drugs.

Published
21 December 2011
From
UCSF Today
Immediate ART during Early HIV Infection May Delay Disease Progression

People who started combination antiretroviral therapy (ART) within 6 months of HIV infection were less likely to experience large CD4 cell decreases or AIDS-related illnesses during follow-up, although viral load set point could not be evaluated, researchers reported.

Published
19 December 2011
From
HIVandHepatitis.com

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