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Some chimpanzees infected with AIDS virus may harbor protective, humanlike gene

When Peter Parham’s postdoc first showed him data suggesting a gene in some wild chimpanzees infected with the AIDS virus closely resembled one that protects humans from HIV, he was skeptical.

Published
12 hours ago
From
Science
Acute HIV infection may present in many ways – sometimes as a serious illness

A Swiss study of people who were diagnosed during early HIV infection has found that a quarter of them presented or developed a wide variety of non-typical

Published
27 May 2015
By
Gus Cairns
Six questions about HIV/AIDS that deserve more attention

As HIV investigators work to control and eradicate the virus worldwide, certain myths or misconceptions about the disease have been embraced, whereas other concepts with merit have been left relatively unexplored, argues American HIV/AIDS researcher Jay Levy, M.D., in a Trends in Molecular Medicine commentary. He calls on fellow researchers to continue questioning and not to lose sight of alternative strategies that could ultimately lead to a sustainable, long-term solution to HIV infection.

Published
15 April 2015
From
Eurekalert Inf Dis
HIV spreads like internet malware and should be treated earlier

A new model for HIV progression finds that it spreads in a similar way to some computer worms and predicts that early treatment is key to staving off AIDS. HIV specialists and network security experts at UCL noticed that the spread of HIV through the body using two methods -- via the bloodstream and directly between cells -- was similar to how some computer worms spread through both the internet and local networks respectively to infect as many computers as possible.

Published
07 April 2015
From
Eurekalert Inf Dis
HIV can spread early, evolve in patients' brains

HIV can genetically evolve and independently replicate in patients' brains early in the illness process, an analysis of cerebral spinal fluid has found. Prompt diagnosis and treatment with antiretroviral therapy should reduce the risk that the virus could find refuge and cause damage in the brain, where some medications are less effective -- potentially enabling it to re-emerge, even after it is suppressed in the periphery, say researchers.

Published
27 March 2015
From
Eurekalert Inf Dis
Inflammation and gut leakage remains elevated in people with HIV despite early antiretroviral treatment

Inflammatory changes and damage to the gut begin very soon after initial HIV infection, and may not return to normal even when people start antiretroviral therapy (ART)

Published
16 March 2015
By
Liz Highleyman
Does HIV make you fat? Study connects viral load with fat gains

HIV infection, or inflammatory changes associated with it, may be responsible for fat accumulation and body fat redistribution, rather than HIV drugs, the Conference on Retroviruses and

Published
06 March 2015
By
Gus Cairns
Two Strains of HIV Cut Vastly Different Paths

It’s now clear, researchers say, that HIV originated in humans on 13 separate occasions, evolving in humans from ancestral viruses that infected monkeys, chimpanzees and gorillas.

Published
03 March 2015
From
New York Times
Gorilla origins of the last two HIV-1 lineages confirmed

Two of the four known groups of human AIDS viruses (HIV-1 groups O and P) have originated in western lowland gorillas, according to an international team of scientists. HIV-1, the virus that causes AIDS, has jumped species to infect humans on at least four separate occasions, generating four HIV-1 lineages -- groups M, N, O, and P. Previous research from this team found that groups M and N originated in geographically distinct chimpanzee communities in southern Cameroon, but the origins of groups O and P remained uncertain.

Published
03 March 2015
From
Eurekalert Inf Dis
HIV Likely Evolved to Enter Latent State Because This Fuels Survival

A pair of new studies suggest that HIV evolved to enter into a latent state in order to thrive in the long run, and that the virus itself, and not infected immune cells, controls when replication stops and starts.

Published
02 March 2015
From
AIDSMeds
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