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How a House Finch Disease Reshaped What We Know About Epidemics

One team of researchers was able to study a highly virulent disease in House Finches. Their recent paper in PLOS Biology sheds light on what makes some disease-causing microbes, or pathogens, more harmful than others.

Published
30 January 2014
From
Cornell Lab of Ornithology
How HIV Destroys Immune Cells

HIV leads to AIDS primarily because the virus destroys essential immune cells called CD4 T cells, but precisely how these cells are killed has not been clear. Two papers published simultaneously today (19 December) in Nature and Science reveal the molecular mechanisms that cause the death of most CD4 T cells in lymphoid tissues, the main reservoir for such cells, during infection.

Published
20 December 2013
From
The Scientist
Aggressive HIV strain leads to faster AIDS development

The new recombinant strain from West Africa speeds up the time taken from the infection stage to the development of AIDS, to around five years.

Published
28 November 2013
From
UPI
HIV may be becoming less fit as it adapts to the immune system

HIV, at least in some parts of the world, may be developing a lower replicative capacity as it adapts to variations in the human immune system, studies

Published
08 November 2013
By
Gus Cairns
Understanding a global epidemic: Why Africans with HIV are more susceptible to TB

Yale researchers have identified a common genetic variant that makes people infected with HIV much more susceptible to tuberculosis (TB). The study is published in the online Early Edition of the Proceedings of the National Academy of Sciences.

Published
24 July 2013
From
Yale University press release
GHANA: Mold Toxins Tied to AIDS Epidemic

A new study has examined the impact of aflatoxins on the AIDS epidemic in Africa. Aflatoxins are poisons produced by aspergillus fungi that can be found on damp grains, nuts, and beans, usually in hot humid climates. They have also been found to be immunosuppressive, possibly causing increased immunosuppression in HIV-positive individuals.

Published
24 July 2013
From
CDC National Prevention Information Network
The immune system, HIV, and aging

The purpose of this brief report is to outline current scientific knowledge regarding the immunologic connections between HIV and aging, and provide an introduction to some of the unresolved questions that are being addressed—or need to be addressed—by research.

Published
07 June 2013
From
TAG
Women with HIV shown to have elevated resting energy expenditure

Studies have shown that about 10 per cent of men infected with human immunodeficiency virus (HIV) have an elevated resting energy expenditure (REE). Now a study has shown that REE is also higher in women with HIV, even when they are on HIV treatment.

Published
17 April 2013
From
Science Daily
Innate immune system can kill HIV when a viral gene is deactivated

Human cells have an intrinsic capacity to destroy HIV. However, the virus has evolved to contain a gene that blocks this ability. When this gene is removed from the virus, the innate human immune system destroys HIV by mutating it to the point where it can no longer survive.

Published
29 March 2013
From
Medical Xpress
French researchers report 14 patients in 'remission' after controlling HIV for over 4 years off treatment

Two weeks ago, the announcement that a baby had been ‘functionally cured’ of HIV disease with the use of very early antiretroviral therapy (ART) caused great excitement at the

Published
16 March 2013
By
Gus Cairns
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