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Starting HIV treatment early and then interrupting is no better than delaying it

A French study that looked at the total amount of time since infection that people with HIV have spent with a detectable viral load has found that,

Published
22 January 2015
By
Gus Cairns
Elite controllers may pay a high price for their low viral load

About one in 200 people with HIV maintains an undetectable viral load and high CD4 counts without having to take antiretroviral therapy (ART). These so-called ‘elite controllers’

Published
07 January 2015
By
Gus Cairns
HIV vaccines should avoid viral target cells, primate model study suggests

Vaccines designed to protect against HIV can backfire and lead to increased rates of infection. This unfortunate effect has been seen in more than one vaccine clinical trial. Scientists at Yerkes National Primate Research Center, Emory University, have newly published results that support a straightforward explanation for the backfire effect: vaccination may increase the number of immune cells that serve as viral targets.

Published
04 January 2015
From
EurekAlert
Could HIV make hearing worse?

A new study has found that low- and high-frequency hearing is poorer in adults with the human immunodeficiency virus, compared with adults who do not have the disease. Although unexpected, similar hearing loss has previously been observed to be more likely in adults with diabetes mellitus. "It is possible that both HIV infection and diabetes, being systemic diseases, could affect the neural function of the cochlea," the authors suggest.

Published
29 December 2014
From
Medical News Today
HIV has become more virulent over time, not less, European study finds

The largest cohort study ever to look at CD4 count and viral loads in HIV-positive people around the time of diagnosis has found evidence that HIV, at

Published
10 December 2014
By
Gus Cairns
Starting HIV Meds Within a Year of Infection Helps Restore CD4s

Beginning treatment for HIV within a year of infection improves the likelihood of returning an individual’s CD4 count to a normal level.

Published
03 December 2014
From
AIDSMeds
HIV virulence depends on where virus inserts itself in host DNA

The human immunodeficiency virus (HIV) can insert itself at different locations in the DNA of its human host -- and this specific integration site determines how quickly the disease progresses, report researchers at KU Leuven's Laboratory for Molecular Virology and Gene Therapy. The study was published online today in the journal Cell Host & Microbe.

Published
13 November 2014
From
Leuven University, via Eurekalert
The genetics of coping with HIV

We respond to infections in two fundamental ways. One is 'resistance,' where the body attacks the invading pathogen and reduces its numbers. Another, which is much less well understood, is 'tolerance,' where the body tries to minimize the damage done by the pathogen. A study using data from a large Swiss cohort of HIV-infected individuals gives us a glimpse into why some people cope with HIV better than others.

Published
12 November 2014
From
Science Daily
Immune cells proposed as HIV hideout don't last in primate model

The type of immune cell called macrophages, which have been proposed as a 'sanctuary site' of HIV in the brain and other organs, and as a possible cause of HIV-related brain impairment, don't live long enough to serve as reservoirs of HIV, a study in PLoS Pathogens finds.

Published
04 November 2014
From
EATG
HIV's infection tactics could guide AIDS vaccine, study finds

New research that sheds light on the methods and machinery used by HIV to infect cells provides insight into the tricky virus that potentially could guide the development of a vaccine against the virus that causes AIDS, according to U.S. government and other scientists.

Published
09 October 2014
From
Reuters
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