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ART Simplification Does Not Affect Systemic Inflammation in Virologically Suppressed HIV

For virologically suppressed patients infected with HIV, switching to a dual antiretroviral maintenance therapy of atazanavir/ritonavir plus lamivudine does not affect plasma markers of systemic inflammation, according to results published in the Journal of Antimicrobial Chemotherapy.

Published
15 June 2018
From
Infectious Disease Advisor
New findings on inflammation & how it affects people with HIV

“There is a large set of adverse events that HIV-infected individuals suffer from that appear to be associated with inflammation,” lead study author Brian Hart told BETA. “These events are relatively common and can affect length and quality of life.”

Published
27 April 2018
From
BETA blog
Inflammation, HIV and marijuana

This issue of TreatmentUpdate focuses on the impact of cannabinoids on the immune system.

Published
13 March 2018
From
CATIE
Study links gut-homing protein levels with HIV infection risk, disease progression

For the first time, scientists have shown a relationship between the proportion of key immune cells that display high levels of a gut-homing protein called alpha-4 beta-7 at the time of HIV infection and health outcomes. Previous research illustrated this relationship in monkeys infected with a simian form of HIV.

Published
26 January 2018
From
National Institutes of Health
SA study shows why some progress to Aids before others

HIV/Aids researchers have never understood why people infected with HIV developed Aids at different times‚ but now they suspect that it all has to do with their genes. A study has now shed new light on how specific genes in people can lead to the faster progression of Aids-related illnesses in people living with HIV who are not on treatment.

Published
25 January 2018
From
Medical Brief
Suboptimal ART adherence associated with greater inflammation in patients with HIV

Recently published findings indicate that suboptimal adherence to ART is associated with activation of coagulation and enhanced residual inflammation among patients with HIV, even if patients have already achieved virologic suppression.

Published
07 January 2018
From
Healio
Scientists find missing clue to how HIV hacks cells to propagate itself

Computer modeling has helped a team of scientists, including several scholars from the University of Chicago, to decode previously unknown details about the process by which HIV forces cells to spread the virus to other cells. The findings, published Nov. 7 in Proceedings of the National Academy of Sciences, may offer a new avenue for drugs to combat the virus.

Published
09 November 2017
From
University of Chicago News
HIV virus fighter linked to cancer mutations

University of Saskatchewan researchers have found the onset of breast, lung and other cancers may be connected to malfunctions of the immune system as it combats specific viruses such as HIV.

Published
26 October 2017
From
University of Saskatchewan
New Study Reveals why people with HIV are more likely to develop Emphysema

Up to 30 percent of HIV patients who are appropriately treated with antiretroviral therapies develop the chronic lung disease emphysema in their lifetime. Now, new research from Weill Cornell Medicine investigators has uncovered a mechanism that might explain why this lung damage occurs.

Published
10 May 2017
From
Weill Cornell Medicine
Pretreatment HIV, immune activation levels determine their persistence during treatment

A study led by a Massachusetts General Hospital investigator finds that pretreatment levels of HIV and immune activation appear to determine the extent to which viral levels and inflammation persist during antiretroviral treatment.

Published
25 April 2017
From
Eurekalert Inf Dis
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