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Many European countries ill-prepared to prevent and control the spread of viral hepatitis

Many countries in the World Health Organization European Region are facing limitations in conducting chronic viral hepatitis disease surveillance, assessing the burden of disease and measuring the impact of interventions, according to results revealed today at The International Liver Congress™ 2015.

Published
23 April 2015
From
Eurekalert Medicine & Health
HCV viral load levels during treatment and speed of decline do not predict cure with interferon-free therapy

Direct-acting antiviral regimens containing sofosbuvir (Sovaldi) and the drugs in Viekirax/Exviera were highly effective regardless of how soon hepatitis C viral load became undetectable after starting treatment, according to

Published
23 April 2015
By
Liz Highleyman
Cancer drug shows promise as cure for hepatitis B

A potential cure for hepatitis B virus infections has been found with a promising new treatment proving 100 per cent successful in eliminating the infection in preclinical models. Australian patients are now the first in the world to have access to the potential treatment -- a combination of an antiviral drug and an anti-cancer drug -- which is in phase 1/2a clinical trials.

Published
21 April 2015
From
Science Daily
Union of South American Nations (UNASUR) proposes centralised purchase of hepatitis C treatments Olysio and Sovaldi for member states

Regional agency UNASUR is aiming to secure price discounts on Sovaldi (sofosbuvir; Gilead Sciences, US) and Olysio (simeprevir; Janssen-Cilag, US), generating savings and reducing the risk of compulsory licences or price cuts.

Published
21 April 2015
From
IHS
Is There Any Good Reason Left to Delay Hepatitis C Treatment?

Physicians increasingly argue that the best choice is to get rid of hepatitis C right away. But your insurance company may not agree. How risky is it to wait for treatment?

Published
17 April 2015
From
Poz
Cepheid announces European approval of Xpert HCV Viral Load

Quantitative test for rapid measurement of hepatitis C virus viral load and confirmation of HCV infection delivers on-demand results in less than 2 hours.

Published
16 April 2015
From
Cepheid press release
Arrowhead initiates phase 2b trial for potential HBV drug

After receiving a clinical hold from the FDA earlier this year, Arrowhead Research Corporation has now been approved by the FDA to begin a multiple-dose phase 2b clinical study of ARC-520 for the treatment of chronic hepatitis B infection, according to a news release from the drug maker.

Published
14 April 2015
From
Healio Hepatology
Merck Faces Hep C Pricing Dilemma to Counter Gilead, Abbvie

Merck has previously stated that it will seek approval for the grazoprevir/elbasvir combination pill in the middle of the year. If approved by the end of the year or in early 2016 -- and there's probably little risk the therapy won't be approved -- Merck's dilemma will be finding a way to grab market share for a new hepatitis C therapy without any clinical or convenience advantages over the existing competition.

Published
09 April 2015
From
The Street
Grazoprevir/Elbasvir, Merck’s Investigational Chronic Hepatitis C Therapy, Granted FDA Breakthrough Therapy Designations

Merck today announced that grazoprevir/elbasvir, an investigational single tablet regimen for the treatment of chronic hepatitis C virus (HCV) infection, has received two new Breakthrough Therapy designations from the U.S. Food and Drug Administration (FDA) for the treatment of patients with chronic HCV genotype 4 (GT4) infection, and for the treatment of chronic HCV genotype 1 (GT1) infection in patients with end stage renal disease on hemodialysis.

Published
09 April 2015
From
Merck press release
At 50 Cents a Pill, Allergy Drug Could Best $1000 Sovaldi, Harvoni

Published today in the journal Science Translational Medicine, researchers from the National Institutes of Health (NIH) reported chlorcyclizine prevented hepatitis C infection in a petri dish and in humanized mice. They said it was effective and did and did not produce any significant cell toxicity when given along with existing drugs to treat hepatitis C.

Published
09 April 2015
From
Healthline

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