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Primary Efficacy and Safety Findings from Phase 3 Study of Janssen's Simeprevir Administered Once Daily Demonstrate Sustained Virologic Response in Treatment-Experienced Genotype 1 Chronic Hepatitis C Adult Patients

Janssen presented SVR12 results from the phase III PROMISE study of simeprevir in treatment-experienced genotype 1 chronic hepatitis C adult patients with compensated liver disease, including all stages of liver fibrosis, when administered once daily with pegylated interferon and ribavirin.

Published
22 May 2013
From
Janssen press release
Recent Advances in the Treatment of Chronic Hepatitis C Threaten to Leave Some Parts of the World Behind

A scenario may develop where hepatitis C is largely eradicated from the developing world but exits in large pockets in developing countries.

Published
21 May 2013
From
Medscape (requires registration)
HIV No Barrier to Getting Liver Transplant

Liver transplants to treat a common type of liver cancer are a viable option for people infected with HIV, according to new research. The Italian study, published in The Oncologist, found that HIV doesn't affect survival rates and cancer recurrence after transplants among HIV patients with hepatocellular carcinoma (HCC).

Published
21 May 2013
From
Web MD
As Hepatitis C Spreads, Scotland Steps In

Scotland is ignoring conventional wisdom and making a bold push to control a virus that may be one of the biggest ticking time bombs in medicine.

Published
17 May 2013
From
Wall Street Journal
Antiretrovirals Linked to Liver Fibrosis

Despite hepatitis B virus suppression provided by current drugs, many patients coinfected with hepatitis B and HIV have advanced liver fibrosis, according to new research.

Published
17 May 2013
From
Medscape (requires registration)
Triple therapy for hepatitis C is effective after liver transplantation, but side-effects are common

Adding the approved HCV protease inhibitor telaprevir (Incivo or Incivek) to pegylated interferon and ribavirin can increase sustained viral response rates even for difficult-to-treat liver transplant recipients, but

Published
16 May 2013
By
Liz Highleyman
Viral Hepatitis. Are You At Risk?

Take this 5 minute Hepatitis Risk Assessment developed by the CDC and get a personalized report.

Published
15 May 2013
From
US CDC
Hepatitis E virus infection can cause rapid liver cirrhosis in people with HIV who have low CD4 cell counts

Infection with hepatitis E virus (HEV) can cause rapid liver fibrosis in people with HIV who have low CD4 cell counts, case reports published in the online

Published
15 May 2013
By
Michael Carter
U.S. FDA Grants Priority Review to Simeprevir (TMC435) for Combination Treatment of Genotype 1 Chronic Hepatitis C

The U.S. Food and Drug Administration (FDA) has granted Priority Review to the New Drug Application (NDA) for simeprevir (TMC435), an investigational NS3/4A protease inhibitor administered as a 150 mg capsule once daily with pegylated interferon and ribavirin for the treatment of genotype 1 chronic hepatitis C in adult patients with compensated liver disease.

Published
13 May 2013
From
Janssen press release
New HCV combinations could have a big role in prevention, but only if treatment rates increase

New combinations of hepatitis C drugs could have major public health benefits, a modelling study published in the online edition of Hepatology shows. Scaling-up treatment rates in

Published
11 May 2013
By
Michael Carter
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