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Possible Mechanism Identified for Efavirenz Tumor-Cell Suppression

Efavirenz may exert a selective cytotoxic effect on tumor cells by activating cannabinoid receptors that mediate tumor toxicity, according to results of new lab studies.

Published
30 September 2013
From
International AIDS Society
HIV and the immune system linked to heart disease in women

Researchers in Boston have intensely studied women, both HIV positive and negative, to better understand the interactions between their immune and cardiovascular systems. They have found that HIV-positive women were more likely to have more sticky deposits in their arteries called plaque, specifically non-calcified plaque (NCP).

Published
27 September 2013
From
CATIE
HPV type 39 linked to anal dysplasia, better screening needed for HIV+ men and women

About two-thirds of gay men and one-fifth of women tested in Spain were found to have cell or tissue abnormalities that could progress to anal cancer, and

Published
25 September 2013
By
Liz Highleyman
Novel vaccine approach to human cytomegalovirus found effective

An experimental vaccine against human cytomegalovirus (CMV) infection, which endangers the developing fetus, organ transplant recipients, patients with HIV and others who have a weakened immune system, proved safe and more effective than previous vaccines developed to prevent infection by the ubiquitous virus.

Published
22 September 2013
From
UC Davis press release
HPV vaccine should be given to boys too, says leader of public health doctors

Ministers urged to extend HPV injections to 12- and 13-year-old boys to tackle growing number of cancers the virus causes

Published
19 September 2013
From
The Guardian
Crofelemer effective for severe or PI-related diarrhea in placebo trial

Crofelemer, a botanically derived agent indicated for symptomatic relief of noninfectious diarrhea in antiretroviral-treated people, proved particularly effective against severe, intransigent diarrhea and protease inhibitor (PI)-related diarrhea in subgroup analyses of a double-blind placebo-controlled trial.

Published
19 September 2013
From
NATAP
TDF/FTC-to-ABC/3TC switch maintains viral suppression, eases bone markers

A switch from tenofovir/emtricitabine (TDF/FTC) to abacavir/lamivudine (ABC/3TC), both with atazanavir/ritonavir, maintained viral suppression through 48 weeks in a noninferiority analysis and improved bone and kidney markers. Four people in the ABC/3TC arm (2%) and one in the TDF/FTC arm (1%) had study-defined virologic failure by week 48.

Published
19 September 2013
From
NATAP
Depression linked to episodes of detectable HIV in cerebrospinal fluid

People who experience episodes of major depressive disorder (MDD) are significantly more likely to have episodes of detectable HIV in their cerebrospinal fluid (CSF), according to an

Published
18 September 2013
By
Liz Highleyman
Old HIV Sidekick Hits Unexpected Patient Group

Pneumocystis jirovecii pneumonia (PCP) -- a hallmark of the early days of the HIV/AIDS pandemic -- still crops up in the era of combination antiretroviral therapy, but, surprisingly, it's seen almost as often in long-term patients as in the newly infected.

Published
17 September 2013
From
MedPage Today HIV/AIDS
One in 5 HIV+ Women in Spanish Group Has Anal Dysplasia, Predicted by Warts

One in 5 women in a Spanish HIV cohort had anal dysplasia, a possible anal cancer precursor, and anal or genital warts raised chances of anal dysplasia more than 11 times.

Published
17 September 2013
From
NATAP

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