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Predictors of HIV-related peripheral neuropathy in the modern era

Researchers at major clinical centres in the U.S. have collaborated to study potential causes of peripheral neuropathy (PN) among HIV-positive people in the modern era. They recruited about 500 people who were free from PN and monitored them for an average of two years, performing extensive assessments. Taking into account many issues, statistical analysis found that there were several factors associated with an increased risk for PN.

Published
01 April 2015
From
CATIE
Researchers develop new model to study why some HPV infections go away and others progress

For people infected with the human papilloma virus (HPV), the likelihood of clearing the infection and avoiding HPV-related cancer may depend less on the body's disease-fighting arsenal than has been generally assumed. A new study finds that the body's ability to defeat the virus may be largely due to unpredictable division patterns in HPV-infected stem cells, rather than the strength of the person's immune response.

Published
01 April 2015
From
EATG
HIV can spread early, evolve in patients' brains

HIV can genetically evolve and independently replicate in patients' brains early in the illness process, an analysis of cerebral spinal fluid has found. Prompt diagnosis and treatment with antiretroviral therapy should reduce the risk that the virus could find refuge and cause damage in the brain, where some medications are less effective -- potentially enabling it to re-emerge, even after it is suppressed in the periphery, say researchers.

Published
27 March 2015
From
Eurekalert Inf Dis
Screening for cryptococcal meningitis and adherence support reduce mortality among people starting ART in Africa

Screening and treatment for cryptococcal meningitis combined with a short period of adherence support has the potential to significantly reduce mortality rates among people with very low

Published
24 March 2015
By
Michael Carter
Good mental health associated with excellent adherence among people taking ART for prevention

Good mental health was the only significant factor associated with optimal pill-taking among people taking antiretroviral therapy (ART) for the prevention of sexual transmission of HIV,

Published
23 March 2015
By
Michael Carter
HIV Patients May Fare as Well as Others With Kidney Transplants

Kidney transplant patients with HIV have similar survival rates as those without HIV, a new study finds. The study included 510 HIV-positive adults who had kidney transplants in the United States between 2002 and 2011. Overall, these patients had similar five- and 10-year survival rates as kidney transplant patients without HIV.

Published
20 March 2015
From
U.S. News & World Report
“An unspoken world of unspoken things”: a study identifying and exploring core beliefs underlying self-stigma among people living with HIV and AIDS in Ireland

Despite evidence that high levels of self-stigma exist among PLHIV, and is experienced to a far greater extent than stigma received from the broader community, there is a paucity of research aimed at understanding causes and functions of self-stigma, and an absence of interventions to mitigate its harmful effects. Understanding the core beliefs underlying self-stigma is therefore essential.This pilot study used a qualitative approach to analyse interviews and written statements to uncover core beliefs underlying self-stigma, the functions thereof, and strategies used to overcome it, among a heterogeneous group of PLHIV in Ireland. See http://www.aidsmap.com/The-diminished-self-HIV-and-self-stigma/page/2657859/, which is based on this project.

Published
18 March 2015
From
Swiss Medical Weekly
FRAX fracture prediction tool underestimates fracture risk in people with HIV

The Fracture Risk Assessment Tool (FRAX), an online tool developed by the World Health Organization and used to help guide decisions about who to screen or treat

Published
18 March 2015
By
Theo Smart
Inflammation and gut leakage remains elevated in people with HIV despite early antiretroviral treatment

Inflammatory changes and damage to the gut begin very soon after initial HIV infection, and may not return to normal even when people start antiretroviral therapy (ART)

Published
16 March 2015
By
Liz Highleyman
Screening may miss pre-cancerous anal lesions in women with HIV

Existing algorithms to screen for anal cancer in women living with HIV could be missing many cases of anal high-grade squamous intraepithelial lesions (HSIL) – abnormal tissue

Published
12 March 2015
By
Theo Smart

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