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Low CD4 count, suboptimal HIV treatment linked to higher anal cancer risk

People with HIV who experienced extensive immune deficiency or who used early antiretroviral drugs before the advent of combination highly-active antiretroviral therapy (HAART) in the mid-90s may be at greater risk for developing anal cancer, according to a retrospective analysis published in the January 28 edition of AIDS.

Published
23 January 2015
From
HIVandHepatitis.com
Substance use and social problems predict HIV infection in American gay men

American gay men reporting depression, childhood sexual abuse, stimulant use, other substance use and heavy alcohol use are nine times more likely than men without any of

Published
20 January 2015
By
Roger Pebody
Dramatic decline in risk for heart attacks among HIV-positive Kaiser Permanente members

Previously reported increased risk of heart attacks among HIV-positive individuals has been largely reversed in recent years for Kaiser Permanente's California patients, according to a study published in the current online issue of Clinical Infectious Diseases. The adjusted risk ratio for heart attacks among HIV-positive study participants went from an 80 percent increased risk in 1996 to no increased risk in 2010-2011. Reported first on Aidsmap at http://www.aidsmap.com/Heart-attack-risk-in-people-with-HIV-may-be-falling-but-not-in-women/page/2834402/ .

Published
19 January 2015
From
Eurekalert
Researchers Delve Into HIV-Infected Population's Aging Risks

Faced with an aging HIV-infected population, international researchers are trying to understand whether the virus or the medications that treat it may accelerate aging. As the life expectancy of those with HIV has increased dramatically since the 1990s because of better medicine, so too has the risk of other chronic diseases typically associated with age, like diabetes, heart disease, osteoporosis and cognitive decline.

Published
15 January 2015
From
Wall Street Journal
Anal Cancer and HPV: What do Gay Men Need to Know?

A CDC recommendation report issued by the Advisory Committee on Immunization Practices released late this summer calls for a better understanding of anal cancer development and screening among a population at high risk—men who have sex with men (MSM). Although there’s still uncertainty about the best way to screen for and treat anal cancer, here’s what we know right now about who gets it, and what to look out for if you’re worried.

Published
14 January 2015
From
BETA blog
Pneumonia risk far higher for HIV-positive children, study shows

HIV-positive children in developing countries are six times more likely to die from pneumonia than children without the virus, research suggests. The first global study into pneumonia deaths in children with HIV has found that, in one year, pneumonia affected 1.4 million children and led to a further 88,000 deaths.

Published
07 January 2015
From
Science Daily
Elite controllers may pay a high price for their low viral load

About one in 200 people with HIV maintains an undetectable viral load and high CD4 counts without having to take antiretroviral therapy (ART). These so-called ‘elite controllers’

Published
07 January 2015
By
Gus Cairns
Bone metastases in prostate cancer blocked by HIV drug

Experiments in mice and in humans have indicated that the HIV drug maraviroc (Celsentri/Selzentry) could be used to prevent the spread of metastases (secondary caners) from prostate and other cancers. Experiments in mice showed a 60% reduction in metastases in animals treated with maraviroc.

Published
04 January 2015
From
Medical news today
Could HIV make hearing worse?

A new study has found that low- and high-frequency hearing is poorer in adults with the human immunodeficiency virus, compared with adults who do not have the disease. Although unexpected, similar hearing loss has previously been observed to be more likely in adults with diabetes mellitus. "It is possible that both HIV infection and diabetes, being systemic diseases, could affect the neural function of the cochlea," the authors suggest.

Published
29 December 2014
From
Medical News Today
Tenofovir-based HIV PrEP does not harm kidneys

Men and women without HIV infection who use tenofovir-based pre-exposure prophylaxis (PrEP) develop significant but not clinically relevant declines in kidney function, according to the largest study to date to look at the issue.

Published
26 December 2014
From
Medscape (requires free registration)
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