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U.S. Food and Drug Administration Approves Descovy® (Emtricitabine, Tenofovir Alafenamide), Gilead’s Third TAF-Based HIV Therapy

-Gilead Sciences, Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved Descovy® (emtricitabine 200 mg/tenofovir alafenamide 25 mg, F/TAF), a fixed-dose combination for the treatment of HIV. Descovy is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients 12 years of age and older. Descovy is not indicated for use as pre-exposure prophylaxis (PrEP) to reduce the risk of sexually acquired HIV-1 in adults at high risk.

Published
05 April 2016
From
Gilead press release
No adverse social consequences from early ART initiation in West Africa

Early initiation of antiretroviral therapy (ART) does not have negative social consequences, investigators report in the online edition of AIDS. Research involving patients in Côte d’Ivoire showed

Published
05 April 2016
By
Michael Carter
African women in London with poor adherence feel that HIV treatment is difficult and unrelenting

A qualitative study with West African women living in London who have difficulties adhering to their HIV treatment has found that many think of HIV treatment as

Published
04 April 2016
By
Roger Pebody
Long-acting oral antiretroviral MK-8591 could represent 'paradigm shift' in HIV treatment and prophylaxis

An investigational antiretroviral agent that maintains drug levels that are able to inhibit HIV up to six months after dosing could represent a “paradigm shift” in HIV

Published
01 April 2016
By
Michael Carter
Gene therapy snips HIV out of infected cells and makes uninfected cells resistant

For the first time, researchers have used a gene-editing technique already used to produce cells resistant to HIV infection to target HIV-infected cells. They have managed

Published
30 March 2016
By
Gus Cairns
Nigerian herbal medicines widely used by HIV positive people can contain antiretrovirals

Herbal medicine use among HIV positive people in Nigeria is widespread, poorly recorded and often precedes ART initiation. Contamination with antiretrovirals is possible and concerning, particularly in untreated people, say the authors of a study of herbal medicine presented at CROI 2016.

Published
24 March 2016
From
HIV i-Base
Scientists Eliminate HIV from Genome of Human T-Cells

A specialised gene editing system designed by scientists at the Lewis Katz School of Medicine at Temple University is paving the way to an eventual cure for patients infected with HIV. In a study published online this month in the Nature journal, Scientific Reports, the researchers show that they can both effectively and safely eliminate the virus from the DNA of human cells grown in culture.

Published
23 March 2016
From
Temple University
ART has averted over 850,000 HIV-related opportunistic infections in low and middle income countries

Rollout of antiretroviral therapy (ART) in low and middle income countries has averted over 850,000 cases of HIV-related opportunistic infections at a saving of at least $47 million

Published
21 March 2016
By
Michael Carter
Combination inhibitor BMS-986197 demonstrates good activity against HIV in early study

A long-acting bio-engineered molecule with a triple mechanism of action demonstrated potent antiviral activity and worked against HIV that developed resistance to any one of the three

Published
18 March 2016
By
Liz Highleyman
Starting HIV therapy associated with improvements in liver function, especially when viral load is suppressed

Starting antiretroviral therapy is associated with improvements in liver function in HIV-positive men with and without viral hepatitis co-infection, investigators from the United States report in the online

Published
17 March 2016
By
Michael Carter

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