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Heart attack risk in people with HIV may be falling – but not in women

A number of studies at last week’s Conference on Retroviruses and Opportunistic Infections (CROI) examined whether people with HIV had an elevated risk of heart attack and

Published
10 March 2014
By
Gus Cairns
Viral load rebounds in 35% of people using PI/r monotherapy: results of five-year PIVOT study

A long-term strategy study sponsored by the Medical Research Council (MRC) in the UK reported low rates of serious complications and the potential to reduce drug costs. However, more than a third of people on the PI/r monotherapy group had viral load rebound compared to only 3% of people on standard combination therapy.

Published
10 March 2014
From
HIV i-Base
Reports of a Second Baby Possibly Cured of HIV: Uncertainty Remains

The media is awash with stories relating to a conference presentation by Deborah Persaud from Johns Hopkins University, in which she described the case of an HIV-infected baby who was treated within four hours of birth and now shows no detectable HIV after nine months of follow up.

Published
10 March 2014
From
TAG Basic Science Blog
Novel two-drug maintenance combination works at least as well as triple therapy: stage set for long-lasting injectable formulation

An oral combination therapy of two antiretroviral drugs, the non-nucleoside rilpivirine (Edurant, also in Eviplera/Complera) and the new integrase inhibitor GSK1265744 (744), was at least as effective as

Published
08 March 2014
By
Gus Cairns
Protected T-cells persist and proliferate in HIV gene therapy study

Genetically modified CD4 T-cells lacking CCR5 co-receptors reach high levels in the body and are resistant to HIV infection, potentially enabling people to maintain a low viral

Published
07 March 2014
By
Liz Highleyman
Raltegravir has the edge over two protease inhibitors in three-drug comparison study

In a head-to-head comparison of three drugs presented at the 21st Conference on Retroviruses and Opportunistic Infections (CROI) on Wednesday, the integrase inhibitor raltegravir (Isentress) proved to

Published
07 March 2014
By
Gus Cairns
The 'Boston patients' experience HIV rebound after stem cell transplants

HIV has re-emerged in two Boston men who underwent experimental antiretroviral therapy interruption after receiving bone marrow stem cell transplants for cancer treatment, Timothy Henrich reported yesterday at the

Published
07 March 2014
By
Liz Highleyman
Two new studies point to impact of HIV treatment on transmission in high-HIV-burden African contexts

Two new studies released by Epicentre, the research arm of the international medical humanitarian organization Médecins Sans Frontières/ Doctors Without Borders (MSF) at the Conference on Retroviruses and Opportunistic Infections in Boston this week point to reductions in new HIV infections in areas where HIV treatment has been scaled up. Results also show viral suppression in one Malawian district twice as high as in the US.

Published
07 March 2014
From
MSF
Male life expectancy nine years shorter due to lower male uptake of HIV treatment in rural South Africa

Male life expectancy in rural South Africa has improved far less dramatically than women’s life expectancy since the introduction of antiretroviral therapy, due to a growing disparity in

Published
06 March 2014
By
Keith Alcorn
HIV disappears in 'Los Angeles baby,' doctors say

The girl, who was born in April and is being referred to as the "Los Angeles baby," remains on three standard HIV medications. Because of this, doctors cannot say for certain yet whether the infant is cured or whether the disease has gone into remission.

Published
06 March 2014
From
Los Angeles Times

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