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Protection from HIV Without a Vaccine

Last month, a team of scientists announced what could prove to be an enormous step forward in the fight against H.I.V. Scientists at Scripps Research Institute said they had developed an artificial antibody that, once in the blood, grabbed hold of the virus and inactivated it. The molecule can eliminate H.I.V. from infected monkeys and protect them from future infections.

Published
11 March 2015
From
New York Times
Sofosbuvir/ledipasvir raises some antiretroviral levels in HIV/HCV coinfected people

People with HIV and hepatitis C virus (HCV) co-infection who take sofosbuvir/ledipasvir (Harvoni) to treat hepatitis C along with boosted protease inhibitor antiretroviral regimens may experience changes

Published
10 March 2015
By
Liz Highleyman
Beware Of Sangamo: 20-Year History Of Failures, Misadventures In HIV, And Flawed Approach In B-Thalassemia

Sangamo's purportedly ground-breaking results in HIV with SB-728 do not stand up under close examination. SB-728 has not shown any indication that it can provide a "functional cure" for HIV, does not compare well to today's standard of care, and cannot find a partner. Sangamo refuses to conduct studies that rigorously assess whether their drugs work. This includes the inclusion of a control arm so assiduously avoided by Sangamo's management.

Published
10 March 2015
From
Seeking Alpha
We may need to combine many approaches to achieve a cure, delegates hear

It is unlikely that one single approach will achieve a cure for HIV infection, delegates at a community cure workshop held the day before the Conference on

Published
09 March 2015
By
Gus Cairns
Does HIV make you fat? Study connects viral load with fat gains

HIV infection, or inflammatory changes associated with it, may be responsible for fat accumulation and body fat redistribution, rather than HIV drugs, the Conference on Retroviruses and

Published
06 March 2015
By
Gus Cairns
Markers of Immune Exhaustion Predict Post-Treatment Control in HIV Patients

Biomarkers of immune exhaustion were associated with how long a patient was able to control HIV after treatment was interrupted, according to a study presented at CROI 2015.

Published
05 March 2015
From
The Body
Pakistan: Factory making fake Hepatitis C drug raided

Assisted by the Federal Investigation Authority (FIA), personnel of the Drug Regulatory Authority of Pakistan (DRAP) raided one of the local industries in Islamabad’s Kahuta industrial area here Saturday, leading to the discovery of unlawful manufacturing of Sofasbuvir tablets, which are used for the treatment of Hepatitis C, and Everlong tablets, the registration of which has long been withdrawn.

Published
04 March 2015
From
The International News
Study of potential HIV 'cure' wins FDA nod

The trial at the City of Hope medical center will take blood-producing stem cells from patients infected with HIV and use a kind of molecular scissors — enzymes called zinc finger nucleases — to edit a protein that the virus uses to infect cells. The method was developed by Richmond's Sangamo BioSciences Inc.

Published
04 March 2015
From
San Francisco Business Times
HIV attachment inhibitor BMS-663068 safe and effective in phase 2b study

Bristol-Myers Squibb's BMS-663068 or fostemsavir, a first-in-class HIV attachment inhibitor that stops the virus from binding to and entering cells, was well-tolerated and demonstrated good antiviral activity in

Published
04 March 2015
By
Liz Highleyman
Early HIV treatment and isoniazid prophylaxis: why TEMPRANO results do not yet support universal ART at CD4 >500 cells/mm3

The TEMPRANO study presented as a late breaker oral presentation, included important information for timing of TB prophylaxis and the timing of ART in TB-endemic countries. The conclusions though do not support universally starting treatment at CD4 counts >500 or answer the primary question of the international START study.

Published
03 March 2015
From
HIV i-Base

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