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Interaction between steroid injections and HIV protease inhibitors can disrupt cortisol levels

Corticosteroid injections can lead to dysfunctions in cortisol levels in people taking HIV protease inhibitors, according to research published in the online edition of the Journal of Acquired

Published
1 hour ago
By
Michael Carter
Prompt HIV diagnosis and early antiretroviral therapy especially important for older people

Prompt HIV diagnosis and early antiretroviral therapy are especially important for older people, results of a UK study published in Age and Ageing show. There was a

Published
19 June 2013
By
Michael Carter
'I don't want to be only person cured of HIV'

Timothy Ray Brown, a native of Seattle who was the first person cured of the AIDS virus, is joining with scientists at the Fred Hutchinson Cancer Research Center to help extend the cure to others.

Published
18 June 2013
From
The Seattle Times
Early Treatment May Do More Harm Than Good in Poor Regions

While U.S. treatment guidelines recommend universal HIV treatment, the benefits of such a policy may not outweigh the costs in resource-poor global areas. Three researchers from Johns Hopkins University published a paper in Clinical Infectious Diseases, arguing that the limited scope and inconsistent availability of antiretrovirals (ARVs), as well as diminished laboratory monitoring capacity, prompt ethical considerations about applying U.S. treatment standards to impoverished countries at this time.

Published
18 June 2013
From
AIDSMeds
Tenofovir Alafenamide Fumarate (TAF) Sign-On Letter to Gilead

With a phase II clinical trial of tenofovir alafenamide fumarate (TAF) yielding encouraging preliminary results and regulatory planning for TAF-inclusive fixed-dose combinations (FDCs) under way, we are compelled to reach out to you regarding the need for a stand-alone formulation of the drug.

Published
17 June 2013
From
Treatment Action Group
Hyaluronic acid levels can predict risk of serious liver events in people living with HIV and hepatitis B or C co-infection

A simple blood test can predict the risk of liver-related death or hepatic encephalopathy for people living with HIV who have hepatitis B or hepatitis C

Published
17 June 2013
By
Michael Carter
Low CD4 cell count increases the risk of several cancers after starting HIV therapy

A large US study has provided important new insights into the incidence and timing of cancers among people taking antiretroviral therapy. Published in the online edition of

Published
12 June 2013
By
Michael Carter
New Danish results spark interest for future HIV cure research

Danish scientists have been doing some interesting cure research that may have gone underappreciated.

Published
12 June 2013
From
CATIE
New FDA Guidance for Industry: Developing Antiretroviral Drugs for Treatment

Significant changes from the 2002 version include: more details on nonclinical development of antiretroviral drugs; a greater emphasis on recommended trial designs for HIV-1-infected heavily treatment-experienced patients (those with multiple-drug resistant virus and few remaining therapeutic options); use of a primary endpoint evaluating early virologic changes for studies in heavily treatment-experienced patients; and use of the traditional approval pathway for initial approval of new antiretrovirals with primary analysis time points dependent on the indication sought.

Published
11 June 2013
From
US Food and Drug Administration
High rate of spontaneous disease regression in men with high-grade pre-cancerous anal lesions

High-grade pre-cancerous anal lesions are more likely to regress than progress, according to Australian research published in the online edition of AIDS. The study involved 574 men, three-quarters

Published
10 June 2013
By
Michael Carter
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