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HIV treatment in children news

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HIV treatment in children
US FDA approves Bristol-Myers' sNDA for Sustiva in HIV-1 infected paediatric patients

The US Food and Drug Administration (FDA) has approved Bristol-Myers Squibb Company's supplemental new drug application (sNDA) for Sustiva (efavirenz), including dosing recommendations for HIV-1 infected paediatric patients three months to three years old and weighing at least 3.5 kg. This approval offers a once-daily option as part of a regimen for this population and includes a “capsule sprinkle” administration method for patients who cannot swallow capsules or tablets.

Published
07 May 2013
From
Pharmabiz
HIV treatment in children
Patients in Control: Protest action in Russia - the lives of HIV-positive children are not profitable for distributors

A protest action organized by activists of "Patients in Control" took place in Moscow in front of the office of the largest distributor of ARV medications in Russia ("R-Pharm"). The activists were outraged about the fact that around 20 auctions for antiretrovirals in different regions did not take place because no bids were submitted; half of those tenders were for paediatric formulations.

Published
03 May 2013
From
EATG
HIV in children
Anti-HIV therapy appears to protect children's hearts, NIH network study shows

For children who have had HIV-1 infection since birth, the combination drug therapies now used to treat HIV appear to protect against the heart damage seen before combination therapies were available, according to researchers.

Published
23 April 2013
From
National Institutes of Health (press release)
HIV treatment in children
Lopinavir/ritonavir equivalent to nevirapine in Ugandan children

A ritonavir-boosted lopinavir (LPV/r)-based regimen achieved a comparable rate of virologic suppression when compared to a non-nucleoside reverse transcriptase inhibitor (NNRTI)-based regimen in HIV-infected Ugandan children at 48

Published
14 March 2013
By
Carole Leach-Lemens
Delivery of care
HIV Care In Resource-Limited Setting Significantly Improved By Computerized Reminders

A large randomized controlled study is among the first to rigorously demonstrate that health information technology can improve compliance with patient care guidelines by clinicians in resource-limited countries.

Published
11 March 2013
From
HIV / AIDS News From Medical News Today
Opportunistic infections
Continuing cotrimoxazole in children on ART reduces the risk of hospitalisation

Children on ART for more than two years who continued taking daily cotrimoxazole had significantly fewer hospitalisations for malaria as well as for non-malarial infections (notably pneumonia, sepsis

Published
06 March 2013
By
Carole Leach-Lemens
Health monitoring in resource-limited settings
HIV treatment for children is safe and highly effective without laboratory monitoring in large African trial

Children did just as well on antiretroviral therapy without routine laboratory monitoring of CD4 cell counts or drug side-effects as those who received regular monitoring during four

Published
05 March 2013
By
Keith Alcorn
The search for a cure
Case report of a 'functional' HIV cure in a child

Researchers in the United States say that they have identified a case of a 'functional' HIV cure in a child infected with HIV who began antiretroviral treatment

Published
03 March 2013
By
Keith Alcorn
GlaxoSmithKline unit joins patent pool for AIDS drugs

GlaxoSmithKline's HIV/AIDS drugs business is to share intellectual property rights on children's medicine in a patent pool designed to make treatments more widely available in poor countries. ViiV and the patent pool have also agreed to negotiate further licenses that will allow generics firms to manufacture low-cost versions of an experimental drug, dolutegravir, that is currently awaiting regulatory approval in Western markets.

Published
27 February 2013
From
Reuters
Malnutrition
Texas: Food availability linked with poor outcomes for HIV-positive children

An HIV-positive child whose family does not have enough good food available is more likely to have a poor clinical outcome, researchers reported. They found that children who did not always have enough to eat had lower CD4 counts as well as higher chances of incomplete viral suppression.

Published
12 February 2013
From
Baylor College of Medicine press release
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