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HIV treatment in children news

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Dolutegravir safe and highly effective in older children

Dolutegravir (DTG) plus optimised background regimen (OBR) is safe, well tolerated and provides virologic efficacy in HIV-infected children from six to 12 years of age at 48

Published
25 February 2016
By
Carole Leach-Lemens
Efavirenz-based treatment is safe and effective for young children with HIV exposed to nevirapine for PMTCT

Efavirenz-based treatment is a safe and effective treatment option for children living with HIV previously exposed to nevirapine for the prevention of mother-to-child transmission (PMTCT)

Published
19 January 2016
By
Michael Carter
Study shows effectiveness of switching antiretroviral therapy for HIV-infected children

A Columbia University study evaluated whether HIV-infected children in South Africa who had achieved viral suppression with one antiretroviral treatment could transition to efavirenz-based therapy, the recommended drug for children older than three years, without risk of viral failure. The researchers reported that the treatment program resulted in excellent sustained virological control.

Published
06 November 2015
From
Eurekalert Inf Dis
Children With HIV More Likely to Die of Malaria

Children infected with H.I.V. appear much more likely than those who are not to die with severe malaria, a new study has found. It may make sense to give these children malaria drugs protectively, the authors said.

Published
01 October 2015
From
New York Times
Can’t Swallow a Pill? There’s Help for That

“Age doesn’t really impact your ability to swallow a pill,” said Dr. Kathleen Bradford, a professor of pediatrics at the University of North Carolina at Chapel Hill. “A teenager can have just as many problems as a 5-year-old. It likely has to do with anxiety and the negative associations with swallowing a pill.”

Published
22 September 2015
From
New York Times
Intensification of antiretroviral therapy reduces risk of late-term mother-to-child HIV transmission

Maternal and infant antiretroviral therapy (ART) intensification is very effective in preventing HIV transmission during labour and birth in pregnant women with HIV in Thailand who present late

Published
29 July 2015
By
Carole Leach-Lemens
Young woman stays undetectable for twelve years off treatment after early HIV therapy

The 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2015) heard today of a case where a young woman, who was infected with

Published
21 July 2015
By
Gus Cairns
High treatment failure rate among Thai children switching to second-line ART

There is a high treatment failure rate among children taking second-line antiretroviral therapy (ART), Thai investigators report in the online edition of Clinical Infectious Diseases. Therapy was

Published
20 April 2015
By
Michael Carter
Kids Who Start HIV Treatment With Low CD4s Largely Regain Them

HIV-positive children who have low CD4 counts when starting treatment by and large experience a rebound to normal levels of those immune cells. After two years on HIV meds, 92 percent of the children achieved a CD4 count of 500 or above. Just nine children (1 percent) experienced an AIDS-defining illness during treatment. Children starting with fewer than 200 CD4 cells/mm3 took 1.29 years to reach a CD4 count over 500 cells/mm3.

Published
07 April 2015
From
AIDSMeds
Week-on, weekend-off treatment controls viral load in young people

Taking an efavirenz-based antiretroviral regimen during the week and taking no medication on two days over the weekend was just as effective as daily treatment in controlling

Published
25 February 2015
By
Keith Alcorn
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