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EMA Recommends First-Line Anti-TB Drugs for Children

The European Medicines Agency (EMA)'s Committee for Medicinal Products for Human Use (CHMP) agrees with the World Health Organization (WHO) dosing recommendations for ethambutol, isoniazid, pyrazinamide, and rifampicin as first-line antituberculosis medicines used in children, according to new EMA dosing guidelines released February 17.

Published
27 February 2012
From
Medscape (requires free registration)
Etravirine proves safe in children and adolescents in pilot trial

Etravirine, one of the newer nonnucleoside reverse transcriptase inhibitors (NNRTIs), was well tolerated in a pilot trial that enrolled children and adolescents. Concentrations achieved with a dose of 5.2 mg/kg were generally equivalent to those attained by adults taking the standard dose.

Published
21 February 2012
From
International AIDS Society
UK guidelines on treatment of HIV in pregnancy give green light to efavirenz

New UK draft guidelines on the management of HIV infection in pregnant women recommend that efavirenz-based treatment should no longer be avoided in pregnant women or women who

Published
17 February 2012
By
Keith Alcorn
Use of some anti-HIV drugs during pregnancy linked to cleft lip and palate; investigators urge cautious interpretation of results

US investigators have identified a possible association between the use of antiretroviral therapy during pregnancy and an increased risk of having a baby with a cleft lip

Published
09 February 2012
By
Michael Carter
Psych Signs Common in Kids With HIV

In a snapshot study of children and adolescents with HIV, about a third met criteria for at least one psychiatric disorder, researchers reported.

Published
06 February 2012
From
MedPage Today HIV/AIDS
Contraception in HIV prevention trials: injectable hormonal methods more effective?

Women using injectable (hormonal) contraceptives had a significantly lower rate of pregnancy compared to those using oral contraception in a major HIV prevention study, researchers report in

Published
02 February 2012
By
Carole Leach-Lemens
Medicalizing HIV: Will Social Services Get Squeezed Out?

OAKLAND Calif Major medical breakthroughs over the past year in the treatment of HIVAIDS are setting off some surprising alarm bells While praised for their lifesaving potential they are causing a change in the dynamics of HIVAIDS care they are causing a change in the dynamics of HIV/AIDS care – a shift that may squeeze out social services needed to support patients while they’re in treatment.

Published
20 January 2012
From
New American Media
Can speeding up nevirapine clearance reduce the risk of resistance after PMTCT use?

In a bid to reduce the risk of nevirapine resistance after the use of single-dose nevirapine to prevent mother-to-child HIV transmission, several research groups are now experimenting with

Published
20 January 2012
By
Carole Leach-Lemens
U.S. Food and Drug Administration Approves New Formulations of Viread(R) for Use by Children Living With HIV

(BUSINESS WIRE) -- Gilead Sciences, Inc. (Nasdaq:GILD) announced today that the U.S. Food and Drug Administration (FDA) has approved Viread(R) (tenofovir disoproxil fumarate) in combination with other antiretroviral agents for the treatment of HIV-1

Published
19 January 2012
From
CNBC
KENYA: The downside of male involvement in PMTCT

Involving men is increasingly being promoted as a key element in the prevention of mother-to-child transmission of HIV, and while its benefits are well-documented - in one Kenyan study it reduced the risks of vertical transmission and infant mortality by more than 40 percent compared with no involvement - it can occasionally lead to domestic discord and even violence.

Published
16 January 2012
From
IRIN Plus News

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