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Dolutegravir may cause birth defects, European Medicines Agency warns

Regulatory agencies in the United States and European Union have warned that women with HIV who can become pregnant should not use the integrase inhibitor

Published
11 hours ago
By
Keith Alcorn
Potential safety issue affecting women living with HIV using dolutegravir at the time of conception

WHO advises that countries and ministries follow the existing 2016 WHO Consolidated ARV Guidelines, and consider the following: Pregnant women who are taking DTG should not stop their ARV therapy and should speak with their health provider for additional guidance. If other first‐line ARVs cannot be used in women of childbearing age, DTG may be considered in cases where consistent contraception can be assured.

Published
16 hours ago
From
World Health Organization
Why the Dolutegravir Pregnancy Warning is Important — and What We Should Do Now

Based on the widespread and growing use of DTG-based regimens globally, these data on the potential risks of becoming pregnant while receiving DTG have immediate and broad clinical relevance.

Published
16 hours ago
From
NEJM Journal Watch
New study suggests risk of birth defects in babies born to women on HIV medicine dolutegravir

The European Medicines Agency (EMA) is evaluating preliminary results from a study which found 4 cases of birth defects such as spina bifida (malformed spinal cord) in babies born to mothers who became pregnant while taking dolutegravir. While EMA is assessing the new evidence, dolutegravir should not be used in women seeking to become pregnant.

Published
16 hours ago
From
European Medicines Agency
More than half of children living with HIV still without treatment in high burden, PEPFAR-supported southern African countries

Data across 20 countries receiving PEPFAR support showed 56 percent of children living with HIV under the age of 15 — an estimated 750,000 children — are not receiving the life-saving treatment that also prevents transmission of the virus.

Published
18 May 2018
From
Science Speaks
What needs to be done to Fast-Track social protection to end AIDS?

In 2016, Member States agreed a set of targets at the United Nations High-Level Meeting on Ending AIDS to be met to put the world on course to end the AIDS epidemic by 2030. One of those targets was to strengthen national social and child protection systems to ensure that, by 2020, 75% of people living with, at risk of or affected by HIV benefit from HIV-sensitive social protection.

Published
09 May 2018
From
UNAIDS
Irish mums diagnosed with HIV worry more about how diagnosis will affect family than themselves, study finds

Aside from worrying about passing HIV on, these mothers tend to prioritise the needs of the family at the expense of their own healthcare on a day-to-day basis

Published
08 May 2018
From
Irish Mirror
Mother-to-child HIV transmission at all-time low in the UK but around two-thirds of reported cases involve women diagnosed after delivery

Factors such as uncertain immigration status, housing problems and intimate partner violence are common among women who pass on HIV to their infants in the

Published
02 May 2018
By
Michael Carter
Anti-HIV drug combination does not increase preterm birth risk, study suggests

A drug combination aimed at preventing transmission of HIV from a pregnant woman to her fetus likely does not increase the risk for preterm birth and early infant death, according to a re-analysis of two studies funded by the National Institutes of Health. The research appears in the New England Journal of Medicine.

Published
26 April 2018
From
National Institutes of Health
What are the outcomes for adults who were born with HIV?

Among people who were born with HIV and have now transitioned to adult care at St Mary’s hospital in London, 80% have an undetectable viral load,

Published
25 April 2018
By
Roger Pebody
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

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