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Drug interactions and pharmacokinetics news

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Study: HIV can hide and grow in 'sanctuaries' in body after it's undetectable in blood

The latest study appears to show a different type of "sanctuary," as the researchers called it, harboring cells with low levels of HIV replication that move into the blood. This suggests that virus growth could occur in a place where drug concentrations are very low.

Published
28 January 2016
From
Washington Post
People taking a large number of non-HIV-related medications more likely to stop or change HIV drugs

HIV-positive patients who are taking a large number of medications for the treatment of non-HIV-related conditions are at increased risk of stopping or changing their antiretroviral therapy (ART),

Published
27 January 2016
By
Michael Carter
Many patients on new HCV medications at risk of drug-drug interactions

Many patients taking direct acting antivirals (DAA) to treat hepatitis C virus (HCV) are at risk of clinically significant drug-drug interactions (DDIs), new research shows.

Published
23 December 2015
From
Medscape (requires free registration)
Study reveals potential challenges for scaling up of HCV therapy in UK

A large proportion of patients with chronic hepatitis C virus (HCV) infection in the UK have co-morbidities, hazardous use of drugs and alcohol and are taking medications that

Published
24 November 2015
By
Michael Carter
How do we maximise global HIV treatment access? IAPAC Care Continuum Guidelines make recommendations

IAPAC, the International Association of Practitioners in AIDS Care, has issued a set of guidelines that aims to establish a common set of best practices to ensure

Published
09 November 2015
By
Gus Cairns
Oestrogen may block HIV reactivation, hints at gender differences in viral reservoirs

Oestrogen receptors on cells may play a role in HIV latency and reactivation, and drugs targeting these receptors could potentially be used to either promote reactivation of

Published
08 September 2015
By
Liz Highleyman
HIV-treatment 'booster drugs' are most likely to have dangerous interactions with methamphetamine, mephedrone, MDMA and ketamine

The two drugs involved in HIV treatment that are most likely to have dangerous interactions with recreational and 'chemsex' drugs are the two that do

Published
24 August 2015
By
Roger Pebody
Top five concerns people with HIV have about ageing: Scotland

Through the Positive Persons' Forum and other initiatives, many people with HIV in Scotland have made it clear that they are very concerned about growing older with HIV. We have set out some of these concerns in the infographic below (or view it as a plain online image). The top 5 concerns were confidentiality, the effects of HIV medication, drug interactions, Financial stability and ignorance and stigma.

Published
12 August 2015
From
HIV Scotland-
Intermittent PrEP may be a robust strategy for anal sex – vaginal much less certain

The pharmacodynamics (drug absorption and elimination rates) of the two drugs that comprise Truvada may favour the efficacy of intermittent pre-exposure prophylaxis (PrEP) more than previously thought, at

Published
22 July 2015
By
Gus Cairns
Geriatric HIV: living with multiple medical conditions will become the norm as population ages

In fifteen years' time, the clinical needs of Dutch people living with HIV will have changed substantially due to three quarters of them being over the

Published
16 June 2015
By
Roger Pebody
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