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Scientists have the tools to end the HIV epidemic; they just need better ways to use them

In the past, there was a sense that stopping the HIV/AIDS epidemic would require some radically new biomedical intervention, such as a cure or a vaccine. The growing consensus, however, is that the tools needed to stamp out HIV already exist if they could just be used in the right way.

Published
08 July 2015
From
Nature
Leading Canadian researcher calls for inclusion of co-infected people in large HCV clinical trials

Stephen Shafran from the University of Alberta performed a major review of clinical trials of many DAA-containing HCV therapies used for the treatment of HCV mono-infection as well as HIV-HCV co-infection. Cure rates of HCV are “remarkably similar” in HCV mono-infected and co-infected participants who were treated with the same regimen and who have the same strain (genotype) of HCV.

Published
07 July 2015
From
CATIE
Risks vs rewards: why people with HIV volunteer for 'cure' research

A recent survey of people living with HIV in the United Kingdom found that more than half would participate in a clinical study to develop a cure for HIV, despite this posing a risk to their health. Why would someone choose to do this?

Published
24 June 2015
From
The Conversation
START Making Sense

The story of the START trial will continue to be told for a long time to come. For some it will be a tale of rigorous perseverance in the face of strong counter-prevailing headwinds and ultimate arrival at a result that is solid and conclusive. Others will see a single-minded and aggressive defense of a trial by investigators who refused to accept not only the obvious but also the evidence that rendered their design obsolete and even unethical.

Published
19 June 2015
From
North Carolina AIDS Training and Education Center
Evidence-based policy movement "unhelpful and unscientific"

Dr Flora Cornish, Associate Professor in Qualitative Research Methodology at the London School of Economics, on why the aspirations of the evidence-based policy movement for bottom line answers are unscientific and unhelpful when evaluating the efficacy of community mobilisation in tackling HIV.

Published
01 June 2015
From
International HIV/AIDS Alliance
i-Base Q&A on the START study results

On 27 May 2015, early results showed that the early treatment group did better. One of the surprises is that even at very high CD4 counts, treatment reduces the risk of HIV related illnesses.

Published
28 May 2015
From
HIV i-Base
WHO Advances Research and Development Financing Effort; Global R&D Observatory To Launch In January

World Health Organization members in committee this week took note of a report by the Consultative Expert Working Group on Research and Development: Financing and Coordination (CEWG), which was set up to find ways to fund research on diseases afflicting poor populations which have little market incentive for the private sector. The report included a proposal for a voluntary pooled fund that would focus on the development of effective and affordable health technologies for such neglected diseases.

Published
26 May 2015
From
Intellectual Property Watch
Africa's health centre at the frontline of HIV research

The Africa Centre for Health and Population Studies sits in the HIV capital of the world. The sleek modern building, rising out of an otherwise rustic setting near Mtubatuba in South Africa, attracts world-class researchers looking to wage war against the resilient virus.

Published
26 May 2015
From
The Guardian
Tense debate over ethics of trial on link between HIV, contraception

Thus far, most evidence pertaining to the use of Depo-Provera and the risk of HIV-infection come from observational studies, which can reveal whether two factors are associated with each other, but cannot determine whether one is causing the other to occur. Given this limitation, some scholars are looking to develop a randomised controlled trial, an experimental study that is better at determining cause and effect.

Published
01 May 2015
From
Mail & Guardian
Many people living with HIV willing to take part in cure research, despite its risks

There is a strong interest among people living with HIV in studies towards an HIV cure, with many potential participants willing to consider antiretroviral treatment interruption. Respondents

Published
24 April 2015
By
Roger Pebody
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