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Many people living with HIV willing to take part in cure research, despite its risks

There is a strong interest among people living with HIV in studies towards an HIV cure, with many potential participants willing to consider antiretroviral treatment interruption. Respondents

Published
24 April 2015
By
Roger Pebody
Women in PrEP trial feared they would have to leave study if they reported low adherence

Post-study interviews and computer questionnaires conducted with former participants in a trial of pre-exposure prophylaxis (PrEP) that reported zero effectiveness show that participants concealed their low adherence to

Published
10 April 2015
By
Gus Cairns
Sheena McCormack: helping to prepare the world for PrEP

As a clinician who has witnessed the devastating impact of the HIV/AIDS epidemic since the 1980s, Sheena McCormack is enthusiastic about her latest project, the UK Medical Research Council (MRC) PROUD study. As lead investigator, she has been investigating the effect of pre-exposure prophylaxis (PrEP) to protect against HIV infection in high-risk men who have sex with men (MSM). PROUD has shown that PrEP reduces new HIV infections by 86%.

Published
28 March 2015
From
The Lancet
'Give HIV drugs to healthy gay men'

Healthy gay men should be offered daily HIV drugs to prevent infections, say UK Medical Research Council and Public Health England scientists. Their study, on 545 high-risk men, found one case of HIV could be stopped for every 13 men treated for a year. The research team says it would be similar to the pill for women and would not encourage risky sex. The findings have been described as a "game changer" and the NHS is considering how to adopt them.

Published
25 February 2015
From
BBC News
The Search for a Permanent Alternative to HIV Drugs

Researchers Carefully Tailor a Study to Find Patients to Test Going Off Antiretroviral Medication

Published
16 February 2015
From
Wall Street Journal
VOICE trial: Microbicide gel may have stopped two out of three HIV infections – in the women who used it

The final published paper on the VOICE trial in women in three African countries mainly reinforces what conference presentations have already shown: this ambitious trial failed to

Published
09 February 2015
By
Gus Cairns
Failed Trial in Africa Raises Questions About How to Test HIV Drugs

The failure of the VOICE trial of H.I.V.-prevention methods in Africa — and the elaborate deceptions employed by the women in it — have opened an ethical debate about how to run such studies in poor countries and have already changed the design of some that are now underway.

Published
05 February 2015
From
New York Times
New anti HIV drug dolutegravir is effective at low doses

The new anti-HIV integrase inhibitor dolutegravir is a highly potent drug. Alain Lafeuillade, a clinical researcher for 20 years in HIV disease, observed that Dolutegravir is highly effective alone in patients without integrase resistance. "Plasma viral load remained undetectable in my patients, and proviral HIV DNA in cells remained stable with only 50 mg 2 to 3 times a week," he said. He is proposing a low-dose dolutegravir monotherapy trial.

Published
21 January 2015
From
MMD Newswire
Gay men are better at predicting when they won’t have sex than when they will

A study in which a group of HIV-negative gay and bisexual men from New York were asked to predict each day whether they would have sex the

Published
12 January 2015
By
Gus Cairns
Pressure grows for Europe to subsidize HIV prevention drug Truvada

HIV-AIDS organizations are urging European health authorities to approve and subsidize the use of HIV prevention drug Truvada as infections slowly rise across the continent.

Published
02 December 2014
From
Deutsche Welle
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