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Cardiovascular disease news

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NIH launches largest clinical trial focused on HIV-related cardiovascular disease

Researchers have begun enrolling participants in a multicenter international clinical trial to test whether a statin can reduce the risk of heart disease in people with HIV infection, who are up to twice as likely as people without HIV infection to have heart disease.

Published
16 April 2015
From
Eurekalert Inf Dis
Inflammation and gut leakage remains elevated in people with HIV despite early antiretroviral treatment

Inflammatory changes and damage to the gut begin very soon after initial HIV infection, and may not return to normal even when people start antiretroviral therapy (ART)

Published
16 March 2015
By
Liz Highleyman
Studies offer mounting evidence that statins may reduce the risk of heart disease in people living with HIV

Evidence is mounting that statin therapy can prevent the progression of coronary atherosclerosis (hardening and narrowing of the arteries supplying the heart) in people living with HIV, according

Published
10 March 2015
By
Theo Smart
HIV and Cardiovascular Risk: Early Statin Use May Help

People with HIV on antiretroviral therapy (ART) with controlled viral loads may benefit from using statins earlier than typically prescribed to control high cholesterol, according to two studies presented last week at CROI 2015.

Published
06 March 2015
From
BETA blog
Smoking is the main cause of increased risk of heart attack in people with HIV

People living with HIV who smoke have an almost three-fold greater risk of heart attack than HIV-negative smokers, according to Danish data published online ahead of print

Published
28 January 2015
By
Roger Pebody
Dramatic decline in risk for heart attacks among HIV-positive Kaiser Permanente members

Previously reported increased risk of heart attacks among HIV-positive individuals has been largely reversed in recent years for Kaiser Permanente's California patients, according to a study published in the current online issue of Clinical Infectious Diseases. The adjusted risk ratio for heart attacks among HIV-positive study participants went from an 80 percent increased risk in 1996 to no increased risk in 2010-2011. Reported first on Aidsmap at http://www.aidsmap.com/Heart-attack-risk-in-people-with-HIV-may-be-falling-but-not-in-women/page/2834402/ .

Published
19 January 2015
From
Eurekalert
Elite controllers may pay a high price for their low viral load

About one in 200 people with HIV maintains an undetectable viral load and high CD4 counts without having to take antiretroviral therapy (ART). These so-called ‘elite controllers’

Published
07 January 2015
By
Gus Cairns
Smoking doubles risk of death for patients taking HIV therapy

Smoking doubles the mortality risk for people with HIV taking antiretroviral therapy, a study published in AIDS shows. Smokers had an increased risk of death from cardiovascular disease

Published
16 December 2014
By
Michael Carter
HIV-infected adults diagnosed with age-related diseases at similar ages as uninfected adults

HIV-infected adults are at a higher risk for developing heart attacks, kidney failure and cancer. But, contrary to what many had believed, the researchers say these illnesses are occurring at similar ages as adults who are not infected with HIV.

Published
10 December 2014
From
Science Daily
Cardiovascular Disease Risk Missed in Many HIV-Positive Veterans Despite Better Risk-Assessment Tool

A retrospective analysis using the 2013 American College of Cardiology/American Heart Association (ACC/AHA) Guidelines and Pooled Cohort Equations (PCEs) for acute myocardial infarction (AMI) and cardiovascular disease (CVD) risk found that the PCE scores were a much better predictor of 10-year CVD risk than the Framingham risk score in a cohort of more than 15,000 HIV-positive veterans on antiretroviral therapy, according to a presentation at ICAAC 2014, made by Henning Drechsler, M.D., of the University of Texas Southwestern Medical Center.

Published
22 October 2014
From
The Body
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