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HIV/HCV co-infection associated with increased risk of osteoporosis and fractures

Co-infection with HIV and hepatitis C virus (HCV) is associated with increased risks of low bone mineral density (BMD) and fracture, investigators report in the

Published
08 July 2014
By
Michael Carter
CROI 2014: Researchers discuss HIV, aging, and frailty

People living with HIV are at greater risk of geriatric syndromes such as frailty and difficulty with daily activities than HIV negative people of the same age -- and this can have a significant effect upon their quality of life as they age, according to several studies presented at the 14th Conference on Retroviruses and Opportunistic Infections (CROI 2014) last month in Boston.

Published
08 April 2014
From
HIVandHepatitis.com
HIV Drug Linked to Low Bone Density in Babies

In a cohort study, babies of mothers taking tenofovir (Viread) had an average whole-body bone mineral content about 8 grams less than babies whose mothers did not use the drug, according to George Siberry, MD, of the National Institute of Child Health and Human Development in Bethesda, Md

Published
07 March 2014
From
MedPage Today
HIV increases fracture risk, say Danes

HIV infection increases the risk of fractures, Danish investigators report in the online edition of the Journal of Acquired Immune Deficiency Syndromes. The case controlled study used data

Published
04 February 2014
By
Michael Carter
Primary care key to management of patients with HIV infection

The HIV Medicine Association of the Infectious Diseases Society of America has updated its HIV care guidelines to reflect the fact that people with HIV are now living normal life spans, and their physicians need to focus on preventive care, including screening for high cholesterol, diabetes and osteoporosis.

Published
14 November 2013
From
Eurekalert Inf Dis
High prevalence of osteoporosis and osteopenia in young men with HIV

There is an increased prevalence of osteoporosis and osteopenia in young HIV-positive men, Spanish researchers report in the online edition of the Journal of Acquired Immune Deficiency

Published
29 October 2013
By
Michael Carter
HIV-positive people not on antiretrovirals are prone to inflammation-related bone loss

HIV-positive people not taking antiretroviral therapy experienced more bone mineral density loss at the hip and were somewhat more likely to develop osteopenia or osteoporosis than HIV-negative individuals,

Published
16 October 2013
By
Liz Highleyman
TDF/FTC-to-ABC/3TC switch maintains viral suppression, eases bone markers

A switch from tenofovir/emtricitabine (TDF/FTC) to abacavir/lamivudine (ABC/3TC), both with atazanavir/ritonavir, maintained viral suppression through 48 weeks in a noninferiority analysis and improved bone and kidney markers. Four people in the ABC/3TC arm (2%) and one in the TDF/FTC arm (1%) had study-defined virologic failure by week 48.

Published
19 September 2013
From
NATAP
New tenofovir formulation works equally well with less effect on kidneys and bones

Tenofovir alafenamide (TAF), a new formulation that produces higher drug levels in cells but allows for lower dosing, was as effective as the current tenofovir disoproxil fumarate

Published
13 September 2013
By
Liz Highleyman
Low baseline CD4 cell count associated with greater bone loss after starting HIV therapy

A low baseline CD4 cell count is associated with loss of bone mineral density (BMD) during the early years of HIV therapy, US investigators report in the

Published
21 August 2013
By
Michael Carter
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