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Bone problems
Zoledronate Protects HIV Positive Men against Bone Loss for at Least 5 Years

The effects of 2 annual doses of zoledronate persist for at least 5 years in HIV positive men on antiretroviral therapy (ART), according to a New Zealand study published in the March 14, 2012, advance online edition of the Journal of Clinical Endocrinology & Metabolism.

Published
11 April 2012
From
HIVandHepatitis.com
Bone problems
CROI: Switching to Tenofovir Increases Bone Turnover, Raltegravir Can Improve Bone Density

HIV positive people who substituted tenofovir (Viread) for zidovudine (AZT; Retrovir) in their antiretroviral regimen showed elevated levels of biomarkers associated with bone turnover and decreased bone mineral density (BMD), researchers reported at the 19th Conference on Retroviruses and Opportunistic Infections (CROI 2012) last month in Seattle.

Published
11 April 2012
From
HIVandHepatitis.com
Bone problems
HIV treatment reduces risk of fractures

Treatment with antiretroviral drugs reduces the risk of low-impact fractures, according to a case-controlled study published in the on-line edition of AIDS. Investigators compared fracture incidence between

Published
14 February 2012
By
Michael Carter
Bone problems
Vitamin D supplements benefit bone metabolism of younger patients taking tenofovir

Vitamin D supplementation is associated with an improvement in a key marker of bone health in HIV-positive young adults treated with tenofovir, US research published in Clinical Infectious

Published
25 January 2012
By
Michael Carter
Bone problems
Vitamin D May Improve Bone Health in Those Taking Anti-HIV Drug

A new NIH-funded study indicates that taking Vitamin D supplements can help prevent hormonal changes that lead to bone loss amongst patients taking tenofovir (Viread) for the long-term treatment of HIV.

Published
12 January 2012
From
National Institutes of Health press release
Side-effects
Limited evidence that vitamin D supplements of any benefit for patients with HIV

There is only scant evidence that vitamin D supplementation is of benefit for patients with HIV, according to UK investigators writing in the January 28th  edition of

Published
10 January 2012
By
Michael Carter
Bone problems
HIV Worsens Bone Loss After Menopause

Compared to a control group, postmenopausal women with HIV infection had higher rates of bone loss and could well have a higher risk for fracture as they age, according to the researchers who conducted the study.

Published
03 January 2012
From
Medscape (requires free registration)
Side-effects
Raltegravir kinder to bones and body fat than boosted protease inhibitors in Spanish trial

Raltegravir (Isentress)-based treatment appears to have a more favourable impact on fat accumulation and bone metabolism compared to therapy based on a ritonavir-boosted protease inhibitor, according to Spanish

Published
28 November 2011
By
Michael Carter
Bone problems
Patients on HIV therapy have an increased risk of stress and fragility fractures; no link to specific drug

Patients taking antiretroviral therapy have an increased risk of fractures typically associated with low bone mineral density, Danish investigators report in the online edition of AIDS. However, the

Published
28 November 2011
By
Michael Carter
Bone problems
Raltegravir combined with Kaletra associated with good preservation of bone density over 96 weeks

A two-drug antiretroviral combination comprising raltegravir and ritonavir-boosted lopinavir has only a modest impact on bone mineral density, a study presented to the International AIDS Society conference (IAS

Published
19 July 2011
By
Michael Carter
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