Modest kidney function decline in people taking Truvada for PrEP supports need for monitoring
‘On-demand’ rectal microbicide gel has reasonable tolerability and acceptability – daily less so
Almost-certain case of PrEP failure due to drug resistance reported at CROI 2016
Long-acting PrEP injection tolerable and acceptable for male volunteers, but dose adjustment needed
Tenofovir alafenamide PrEP protects monkeys from infection, but rectal and vaginal levels in humans may be too low
Bone density recovers quickly after stopping PrEP
Dose-finding trials of antibody-based drugs for HIV prevention will start soon
