Men who have sex with men (MSM)
Science Magazine | 9 hours ago
“Baby, I was born this way,” Lady Gaga sang in a 2011 hit that quickly became a gay anthem. Indeed, over the past 2 decades, researchers have turned up considerable evidence that homosexuality isn't a lifestyle choice, but is rooted in a person's biology and at least in part determined by genetics. Yet actual “gay genes” have been elusive. A new study of male twins, scheduled for presentation at the annual meeting of the American Society of Human Genetics (ASHG) in Baltimore, Maryland, today, could help explain that paradox. It finds that epigenetic effects, chemical modifications of the human genome that alter gene activity without changing the DNA sequence, may have a major influence on sexual orientation.
Slate | 17 hours ago
The benevolent powers of the vaginal microbiome are even greater than we thought. In addition to aiding fertilization and protecting fetuses during pregnancy, healthy vaginal mucus that’s full of good bacteria can trap and immobilize HIV particles. The study examined the cervicovaginal mucus, or CVM, of 31 women and tested its ability to immobilize HIV particles. CVM samples that contained higher concentrations of D-lactic acid, which only bacteria can produce, did far better than others. The D-lactic acid wasn’t itself a barrier to HIV, but an indicator of something else going on that made certain types of CVM better at trapping the virus than others.
That something was Lactobacillus crispatus, a species of bacteria that could change the way we think about HIV prevention.
Testing policies and guidelines
Science Daily | 17 hours ago
A 'Test and Treat' protocol for HIV/AIDS diagnosis and treatment, implemented in two Guangxi, China counties in 2012, was associated with increased engagement in HIV/AIDS care and a 62 percent reduction in mortality among participants, according to a new study. This before-and-after analysis suggests that broader implementation of the program may inexpensively improve outcomes for HIV-positive individuals in China.
Healthline | 17 hours ago
Once considered part of the gold standard of HIV treatment, alternative regimens can now alleviate concerns about birth defects, psychiatric problems, and even suicide caused by the drug efavirenz. Research published this week shows that three alternative, first-line HIV treatments that do not include efavirenz are just as good at suppressing the virus and are better tolerated.
Men who have sex with men (MSM)
GMFA | 18 hours ago
FS magazine celebrates its 150th issue with the big gay sex survey results. We surveyed over 3,000 gay men and bring you the results. These include finding that two-thirds of gay men used ocndoms the last time they had anal sex, that 69% now know what PrEP is but that only 51% understand what being positive and undetectable means.
Types of HIV tests
HIV / AIDS News From Medical News Today | 07 October 2015
A nanoscale machine composed of synthetic DNA can be used for the rapid, sensitive and low-cost diagnosis of many diseases, including HIV.
Ageing and HIV
NATAP | 07 October 2015
Two thirds of an older French HIV group met criteria for frailty or prefrailty, and half met criteria for "precarious" socioeconomic status in a 509-person prospective analysis . Multivariate analysis linked frailty and 2 or more comorbidities to precariousness, defined by the EPICES (Evaluation of Deprivation and Inequalities in Health Examination Centers) score.
TAG | 07 October 2015
Regulatory filing and review delays keep Truvada as pre-exposure prophylaxis out of reach of those who need it most.
New and experimental hepatitis C treatment
Bristol-Myers Squibb | 07 October 2015
Three applications are under review for Daklinza in combination with sofosbuvir with or without ribavirin to treat chronic hepatitis C patients with decompensated cirrhosis, post-liver transplant recurrence of HCV, and coinfection with HIV-1.
Global health initiatives
Science Speaks | 07 October 2015
In a much anticipated announcement during the Replenishment Conference in New York on Monday and Tuesday this week, the Obama Administration revealed a $4 billion pledge to the Global Fund to Fight AIDS, Tuberculosis and Malaria over the next three years.