The annual Conference on Retroviruses and Opportunistic Infections (CROI 2016) took place in Boston, USA from 22-25 February 2016.

Conference highlights

PrEP

Almost-certain case of PrEP failure due to drug resistance reported at CROI 2016.

Conference bulletins

Conference bulletins, available in English, French, Italian, Portuguese, Russian and Spanish.

Achieving the 90-90-90 target

Botswana close to reaching the 90-90-90 testing and treatment targets.


Transgender people

Trans people are at high risk for HIV, but too little is known about prevention and treatment.

HIV prevention

Vaginal rings containing an anti-HIV drug are moderately effective in preventing HIV.

HIV epidemiology

The lifetime risk of being diagnosed with HIV in the US has decreased but varies widely among population.


Side-effects

Tenofovir treatment raises the risk of broken bones.

Infectiousness

People with HIV considerably overestimate their chance of infecting someone.

New HIV treatment

Combination of long-acting injectable anti-HIV drugs work well as HIV maintenance therapy.


aidsmap news from CROI 2016

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News bulletins

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Tweets from CROI 2016

  • Catch up with news from #CROI2016 - the third of our summary bulletins is out now: https://t.co/jpipSEaZ34 #HIV #PrEP #HepatitisC #TB26 Feb 2016 04:06
  • "The high rate of STIs among #PrEP clients means we are reaching the people at most risk." -- Dr. Golub of @CallenLorde #CROI201626 Feb 2016 01:37
  • Perfect ending for #CROI2016 with the magnificent and solidary talk by Julia del Amo re HIV and Migrants: "how can we test and not treat?"25 Feb 2016 11:01
  • To get to 90-90-90 barriers among migrants must be addressed. Migrants need universal access to #HIV testing says del Amo Valero #croi201625 Feb 2016 10:51
  • Rashida Ferrand: Global antiretroviral coverage in children/adolescents is 34% vs 68% in adults #CROI201625 Feb 2016 10:46
  • How many of the state's w/ highest risk of contracting #HIV have abstinence-only ed in schools? #CROI201625 Feb 2016 10:14
  • Rashida Ferrand: adolescents living with #HIV - only group in whom HIV-related mortality is increasing #CROI201625 Feb 2016 10:06
  • How can we use social media more to effectively communicate with affected youth and adolescents? #CROI2016 #HIVwhome25 Feb 2016 09:29
  • A.Sohn: #HIV no.1 cause of death amongst #adolescents in sub-Saharan #Africa,2nd most common cause globally.Urgent action needed #CROI201625 Feb 2016 09:22
  • Going to the last session of #CROI2016 focused on the HIV hotspots. Finding and focusing interventions in hotspots will stop HIV25 Feb 2016 09:05
  • Fab last day #CROI2016 early treatment, less infctn assoc cancer. Women with high CD4 counts - no inc risk of CIN 2+ compared to controls.25 Feb 2016 08:42
  • Rolling out test and treat and #PrEP for #HIV. Challenges and cost-effectiveness vary in each setting #croi201625 Feb 2016 07:37
  • Adrian Smith: Homonegativity, criminalisation, #stigma prevents access to #HIV prevention and treatment for #MSM worldwide #CROI201625 Feb 2016 06:52
  • The new Tenofovir formulation (TAF) may be distributed differently vs older formulation (TDF), offer LESS protection as #PrEP. #CROI201625 Feb 2016 06:43
  • Household and hospital transmission is the main driver of the XDR-TB epidemic in South Africa #CROI201625 Feb 2016 05:04
  • Elegant genetic studies show United States #HIV came from Caribbean to New York then spread to SFO circa 1970 Abstract 140 #CROI201625 Feb 2016 05:00
  • First documented #PrEP failure - resistance seen in virus unexpected. Likely from #Stribild failure source. #CROI2016 @howardbrownhc25 Feb 2016 04:54
  • The second of our #CROI2016 news summary bulletins is out now: https://t.co/C9le1rhkcp #HIV #PrEP25 Feb 2016 04:54
  • Waked: Egyptian study finds ravidasvir + sofosbuvir cures 95%-100% of genotype 4 #hepC pts w/o & 86%-100% pts with cirrhosis #CROI201625 Feb 2016 04:35
  • Incidence of IDU in non-urban areas more than twice that of urban areas #CROI2016 #maine #harmreduction #treataddiction25 Feb 2016 02:54
  • recognition by law enforcement of drug use as a medical rather than criminal issue key to preventing infectious disease outbreaks #CROI201625 Feb 2016 02:32
  • The importance of syringe programmes highlighted by the HIV outbreak in Scott county, IN, fuelled by blindfolded authorities #CROI201625 Feb 2016 02:25
  • Brooks @CDCgov: Indiana #HIV & #hepC outbreak devastating but entirely preventable #CROI201625 Feb 2016 02:24
  • Brooks- The growing epidemic of opioid abuse & IDU is rising among populations previously considered low-risk for #HIV. #CROI201625 Feb 2016 02:24
  • John Brooks:#Addiction a medical condition,not a crime.Public health must work w/correctional services to provide appropriate care #CROI201625 Feb 2016 02:18
  • We have know for long that harm reduction works, shocking to see that it is not self-evident in some parts of the USA. #CROI2016 #HIV25 Feb 2016 02:18
  • Brooks: In 2014 more US deaths due to drug overdose than auto accidents #CROI201625 Feb 2016 02:17
  • Brooks: We're seeing consequences of war on drugs, need to show law enforcement it’s a public health issue #CROI201625 Feb 2016 02:15
  • John Brooks @CDCgov: 2015 rural Indiana outbreak now 188 new #HIV infections among #PWID, 90% coinfected w/#hepC #CROI201625 Feb 2016 02:06
  • @CDC_HIVAIDS’ Dr. John Brooks details the public health response to an HIV outbreak related to injection drug use in rural IN. #CROI201625 Feb 2016 02:03
  • Eric Rubin: Big clinical trials of #TB treatment have been disappointing, but we'll get there #CROI201625 Feb 2016 02:00
  • Long-acting PrEP injection tolerable and acceptable for male volunteers, but dose adjustment needed https://t.co/r4V5lj7fUU #CROI201625 Feb 2016 01:32
  • Staking my place in the Auditorium early—soundtrack Violent Femmes American Music, good work team. #croi201625 Feb 2016 12:51
  • Positive Voices data shows high rates of chemsex among HIV positive MSM #croi2016 https://t.co/NuTBG2Y1AB25 Feb 2016 12:36
  • My inbox is full of emails about one thing. Vaginal rings. Vaginal rings. #croi2016 #HIV #PrEP @HIVpxresearch @WHO @UNITAID25 Feb 2016 11:06
  • Mallon #CROI2016: Only HIV drug that's solidly tied to BMD loss is tenofovir (the old one, not TAF). Others? Meh, but may increase turnover.24 Feb 2016 10:51
  • Grimsrud: nearly 40k stable ART patients in Cape Town area in adherence clubs. #CROI201624 Feb 2016 10:40
  • A common theme at #CROI2016 - exercise is an important intervention for many chronic conditions affecting HIV+ people24 Feb 2016 10:16
  • Appx 1.2M Americans could benefit from #PrEP, but many providers don’t know about #PrEP & many who are at-risk aren’t using it. #CROI201624 Feb 2016 09:33
  • We need to move from know your partner HIV status to know your partner viral load #CROI2016 says Andreas Jahn from Malawi @PEPFAR24 Feb 2016 09:28
  • Ministry of Health of Malawi, Andreas Jahn sharing the best practice of his country in tackling HIV using option B+ #CROI201624 Feb 2016 09:24
  • Nice update on #Ebola survivors cohort study in #Liberia at #CROI2016 https://t.co/UGqnHOyUJ524 Feb 2016 09:23
  • We have the tools in place to end our nation’s #HIV epidemic, but we must close the gaps in testing, treatment, & prevention. #CROI201624 Feb 2016 09:09
  • #CROI2016 buzzing about #PrEPnavigators to have more open discussion about sex, #PrEP access and STI management24 Feb 2016 07:43
  • Really enjoyed themed discussion on HIV and the #microbiome led by Nichole Klatt #CROI2016 #probiotics #microbiota24 Feb 2016 07:43
  • #CROI2016 microbiome: Fecal transplant is well-tolerated in #HIV men, but did not reproduce #microbiome diversity of donors.24 Feb 2016 07:07
  • Sarit Golub: Folks who are deciding to take #PrEP need it -- if there is an increase in STIs it is outweighed by #HIV protection #CROI201624 Feb 2016 06:40
  • Panel is unanimous:PrEP can be a great chance to reveal STIs.Rather than PrEP driving STIs.Calls out to media to get message out! #CROI201624 Feb 2016 06:34
  • Themes from #CROI2016 so far: how to meet the @UNAIDS 90-90-90 goal, longer lasting prevention & treatment options, & #PrEP PrEP & more PrEP24 Feb 2016 06:23
  • A Liu of @SF_DPH: 4% decline n kidney function assoc w #PrEP use. Improves once stopped. #CROI2016 @WHO @CDC_HIVAIDS @iasociety @jiasociety24 Feb 2016 06:17

Official conference website

Find out more on the official conference website.

Visit the CROI 2016 website >

NAM's coverage of CROI 2016 has been made possible thanks to support from Gilead Sciences and ViiV Healthcare.