Surrogate markers
A surrogate marker is an indirect measure. In HIV disease, morbidity and mortality are direct markers of disease progression; laboratory tests are surrogate markers of disease progression. Surrogate markers in HIV disease include CD4 counts, CD4/CD8 cell ratios, and viral load. Surrogate markers are important in anti-HIV drug trials because the true effects of drugs in slowing HIV disease may not be obvious for many years.
latest aidsmap news
- US Health Department identifies further 18 effective HIV prevention programmes
- More African people acquiring HIV in the UK than previously thought
- HIV prevalence may decline because the most vulnerable are infected and die first
- Lack of perceived need for HIV treatment associated with poor adherence
- TB doesn't always increase HIV viral load
- New 75mg darunavir tablet approved by FDA for use by HIV-positive children
- Thyroid checks recommended for people with HIV
- Knighthood for head of UK HIV charity
- Gay men often not accessing PEP despite risk of HIV exposure
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