Ibuprofen (Brufen / Brufen Retard / Fenbid) is a non-steroidal anti-inflammatory drug (NSAID) that is used to treat pain and inflammation. It is particularly useful in relieving arthritis, period pains, fever and headache. It may also be effective in treating low blood pressure and preventing some types of dementia, although further research is required.

Low doses of ibuprofen are available without prescription in chemists, supermarkets and other shops. The standard dose is 200 to 400mg every four to six hours, with a maximum daily dose of 1200mg. Higher doses can be given under medical supervision.

Ibuprofen’s side-effects include nausea, upset stomach, stomach ulcers or bleeding, liver toxicity, diarrhoea, headache, dizziness, swelling and high blood pressure. These are more severe in patients taking high doses of ibuprofen for long periods.

Ibuprofen is not known to interact with protease inhibitors or non-nucleoside reverse transcriptase inhibitors.