Integrase inhibitors

raltegravir

Names: raltegravir, Isentress 

Dose: One oval pink 400mg tablet twice daily. 

Tips on taking it: take with or without food. 

Common Side‑effects: diarrhoea, nausea and headache. 

Resistance to raltegravir: there is currently little information. 

Key drug interactions: can affect blood levels of tipranavir/ritonavir and atazanavir/ritonavir, but it is not necessary to adjust drug doses because of this. The anti‑TB drug rifampicin can lower blood levels of raltegravir.