Dacarbazine is an approved anti-cancer drug, which is used frequently in combination with other drugs for the treatment of metastatic melanoma and Hodgkin’s disease.

It comes as powder that is reconstituted into a liquid for intravenous injection. It suppresses the bone marrow, causing leukopenia and thrombocytopenia. Other common side-effects include nausea, vomiting and hair loss.

Dacarbazine is manufactured by Bayer under the tradename DTIC-Dome.