Cyclophosphamide is an approved anti-cancer drug which is active, alone or in combination, against a wide spectrum of tumours. It is being tested as a treatment for lymphoma.

It comes either as tablets or as a liquid for intravenous injection. Its most significant side-effects are hair loss, nausea and vomiting. Thrombocytopenia and haemorrhagic cystitis have also been observed.

Cyclosphosphamide is manufactured by Pharmacia & Upjohn. Another version, sold under the brandname Endoxana, is made by ASTA Medica.