Current practice varies from clinic to clinic, and none has a formal, open policy. Lack of policy is in part a result of the complex issues surrounding non–occupational PEP and the paucity of research supporting its use.

A number of centres state that they treated individuals who report recent unprotected sex with an HIV–positive partner. However, they assess these on a case by case basis. Clinics that prescribe PEP are often anxious not to gain a public reputation for doing so, since this might lead to a significant increase in the number of presenting cases, with resulting cost pressures.

Other clinics report that they do not currently offer PEP for sexual or IDU exposure, citing the lack of proof of efficacy and concern over drug toxicities. They argue that if PEP is to be provided, it should be on the basis of clear public guidelines backed by adequate funding.