Outcomes and prognosis

Outcomes and prognosis features

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  How long have I got, doc?

  Can people with HIV really live as long as anyone else? Gus Cairns investigates ...

  From:HIV treatment update

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  Why we won’t die of AIDS

  A study in France has found that, whatever older people with HIV die of, it probably won’t be AIDS. In recent years one of the increasingly hot topics...

  From:HIV treatment update

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  How does HIV make us sick?

  Nearly 30 years after the first documented cases of AIDS, we still don’t know exactly how HIV destroys the immune system. But inflammation – sustained immune activation...

  From:HIV treatment update

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  Adherence and long-term treatment success

  Taking your HIV medication correctly (the technical term for this is adherence) is the single most important thing you can do to make sure your HIV treatment...

  From:HIV treatment update

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  A ‘functional cure’?

  Examining the excitement over a bone marrow transplant that ‘eradicated’ HIV, by Edwin J Bernard. ...

  From:HIV treatment update

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  Can we create ‘elite controllers’?

  Is combination immunotherapy the future? ask Edwin J Bernard and Derek Thaczuk ...

  From:HIV treatment update

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  Defining, and then watching for, treatment failure

  A review of various clinical, immunological and virological definitions of antiretroviral treatment failure in resource-limited settings....

  From:HIV & AIDS treatment in practice

Outcomes and prognosis in your own words

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  Life on HIV treatment – a personal perspective

  I’ve been taking HIV treatment for ten years – that's longer than the average life expectancy of someone with HIV when I was diagnosed back in 1991. I’ve...

  From:In your own words

Outcomes and prognosis news from aidsmap

• Is a viral load just below 50 copies/ml low enough to ensure the long-term success of HIV therapy?

  Suppressing viral load to below 50 copies/ml may not be enough to ensure the long-term success of antiretroviral therapy, according to a UK study published in the March edition of Clinical Infectious Diseases. Using ultra-sensitive viral load assays, ...

  16 January 2012 | Michael Carter

• HIV treatment integrated into general health care delivers 'equal or better' results in MSF programmes

  Outcomes for people taking antiretroviral treatment in Médecins sans Frontières’ (MSF) integrated general healthcare programmes were as good or better than those in vertical HIV programmes, researchers report in a nine-country study published in the advance online edition of the ...

  13 January 2012 | Carole Leach-Lemens

• Big increase in repeat pregnancy rates in HIV-positive women in UK and Ireland

  Rates of repeat pregnancies among HIV-positive women in the UK and Ireland have increased substantially since 1997, investigators report in the online edition of the Journal of Acquired Immune Deficiency Syndromes. In 2009 over a third of all pregnancies ...

  12 January 2012 | Michael Carter

• Similar HIV treatment outcomes among UK gay men across ethnic groups

  HIV treatment outcomes among gay men in the UK are similar across ethnic groups, investigators report in the online edition of the Journal of Acquired Immune Deficiency Syndromes. The study showed that gay men from black and minority ...

  03 January 2012 | Michael Carter

• Would early treatment for everyone be better? Study poses the question

  A US study has found that patients infected with HIV in the previous six months who were given 36 weeks (8.3 months) of antiretroviral therapy (ART) were only a third as likely to need to go back on ...

  21 December 2011 | Gus Cairns

• Adding rituximab to chemotherapy regimens improves outcomes for AIDS-related lymphomas

  The addition of rituximab to chemotherapy regimens for the treatment of AIDS-related lymphomas improves both overall survival and progression-free survival, German investigators report in the online edition of AIDS. Therapy with rituximab appeared to be safe, and no deaths were ...

  14 December 2011 | Michael Carter

• Co-infection with hepatitis B worsens HIV-related outcomes

  Co-infection with hepatitis B virus increases the risk of AIDS or death for patients newly diagnosed with HIV, investigators from the US military report in the online edition of the Journal of Infectious Diseases. Individuals with chronic hepatitis B infection were ...

  13 December 2011 | Michael Carter

• Hepatitis B genotype B associated with poorer liver-related outcomes in Taiwanese patients co-infected with HIV and hepatitis B

  Liver-related outcomes are poorer in HIV-positive patients who are co-infected with hepatitis B virus genotype B compared to co-infected patients with hepatitis B genotype C, Taiwanese investigators report in the online edition of Clinical Infectious Diseases. The prospective, observational study involved ...

  13 December 2011 | Michael Carter

• Earlier deaths in people with HIV due to drugs, alcohol, co-infections, poorly controlled HIV - not rapid ageing

  Patients taking antiretroviral therapy have the same mortality risk as individuals in the general population, according to Danish research published in the open-access journal PLoS One. However, this was only the case when the patients responded to treatment and ...

  12 December 2011 | Michael Carter

• Long-term use of HIV drugs is safe, does not raise risk of death, study shows

  A large international study has provided persuasive evidence of the long-term safety of antiretroviral therapy. Writing in the online edition of AIDS, investigators from the EuroSIDA study report that prolonged use of antiretroviral therapy did not increase the risk ...

  08 December 2011 | Michael Carter

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Outcomes and prognosis news selected from other sources

• New Yorkers' Life Expectancy Rises Due to H.I.V. Testing and Treatment

  The life expectancy for babies born in New York City reached 80.6 years in 2009, the highest level recorded and one that surpasses the national life expectancy rate, Mayor Michael R. Bloomberg said Tuesday.

  03 January 2012 | New York Times

• Kenya: Listen, Your Moment of Truth Is Knocking

  Turning a new leaf - to a new year, to be specific - always brings back memories, mostly sad, about the tough times I had when I tested positive, and it seemed like every single day was my last.

  28 December 2011 | AllAfrica

• HIV/AIDS hospitalizations drop in California

  California has made dramatic gains in reducing the hospitalization rates of people living with HIV and AIDS, but there are still racial disparities, according to a new state report.

  30 November 2011 | Los Angeles Times

• Tailored Risk Profiles Guide Care of HIV Patients

  Patients with HIV are living longer and have more comorbidities. A new index could help clinicians determine who might benefit from screening and measure net benefit for a wide range of interventions for an individual patient.

  17 November 2011 | Medscape (requires free registration)

• Hepatitis C Surpasses HIV as Cause of Death in U.S.

  It’s official. Chronic hepatitis C virus (HCV) infection is associated with more deaths than HIV infection, according to sobering new data presented by the U.S. Centers for Disease Control and Prevention (CDC) on Tuesday, November 8, at the 62nd annual meeting of the American Association for the Studies of Liver Diseases (AASLD) in San Francisco.

  10 November 2011 | AIDSMeds

• Treatment Costs Higher When HIV Diagnosis Is Delayed

  Patients presenting late with HIV incur significantly higher healthcare costs, Maria Martinez-Colubi, MD, from the Ramón y Cajal Hospital in Madrid, Spain, told delegates here at the 13th European AIDS Conference of the European AIDS Clinical Society (EACS).

  01 November 2011 | Medscape (free registration required)

• Standard definition of loss-to-follow-up for ART patients

  A study led by Benjamin Chi of the University of Alabama, Birmingham, USA, and colleagues reports on the development of a standard definition for loss-to-follow-up that can be used by HIV antiretroviral programs worldwide.

  25 October 2011 | Eurekalert Inf Dis

• IDSA: Young Adult HIV Patients in Hospital More Often (CME/CE)

  Adolescents and young adults, ages 17-24, who were perinatally infected with HIV (PHIV) appear to have increased hospitalization rates compared with younger PHIV patients, researchers suggested here.

  25 October 2011 | MedPage Today HIV/AIDS

• 'HIV life expectancy rises' in UK

  Life expectancy for people with HIV in the UK has increased by 15 years in the past decade, thanks to modern drugs and earlier treatment, a study suggests.

  12 October 2011 | BBC Health

• PEPFAR is poised to get on track to end AIDS

  For every 1,000 patient-years of PEPFAR-supported HIV treatment provided, 228 fewer HIV patients die, 449 fewer children become orphans, 61 fewer sexual HIV transmissions occur and 26 fewer “vertical” transmissions (e.g. mother-to-child) occur.

  05 October 2011 | Science Speaks: HIV & TB News

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