CD4 count

CD4 count features

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  Symptoms versus laboratory monitoring as criteria for starting treatment

  In the absence of laboratory monitoring of CD4 counts, how can symptoms be used to determine when to start antiretroviral therapy?...

  From:HIV & AIDS treatment in practice

CD4 count news from aidsmap

• Liver fibrosis increases risk of discordance in CD4 cell count and percentage in HIV-positive people

  Liver fibrosis is associated with discordance between CD4 cell counts and percentages in HIV-positive people, according to US research published in the online edition of Clinical Infectious Diseases. The association was especially marked for patients with a total lymphocyte count below ...

  09 April 2012 | Michael Carter

• Point-of-care CD4 test improves retention and treatment initiation in Mozambique

  The use of a point-of-care CD4 cell count test dramatically reduced the rate of loss to follow-up among patients diagnosed with HIV at clinics in Mozambique and doubled the number of patients who started treatment, according to findings from ...

  28 September 2011 | Keith Alcorn

• Variations in mitochondrial DNA affect CD4 gains in black patients taking successful HIV therapy

  Variations in mitochondrial DNA are associated with poorer CD4 cell gains after the initiation of antiretroviral therapy in non-Hispanic black patients, US investigators report in the online edition of the Journal of Acquired Immune Deficiency Syndromes. Black people who had ...

  09 August 2011 | Michael Carter

• Poor CD4 cell recovery after starting HIV treatment should be a cause for concern, close monitoring needed

  Patients whose CD4 cell count does not recover despite achieving virologic control with HIV therapy require continued medical attention, results of a large European study presented to the recent International AIDS Society conference in Rome show. Researchers found that individuals ...

  01 August 2011 | Michael Carter

• How best to deploy point-of-care CD4 cell testing in resource-limited settings?

  Widespread introduction of point-of-care (POC) CD4 cell tests that don’t require a laboratory technician but can be performed onsite by a nurse, providing results in less than an hour – while the patient waits) is expected in the ...

  19 July 2011 | Theo Smart

• First ever CD4 cell count after primary infection can predict immune restoration during HIV therapy

  The level of a patient’s CD4 cell count shortly after infection with HIV can predict the extent of immune recovery after the initiation of antiretroviral therapy, investigators from the US military report in the online edition of the Journal ...

  09 May 2011 | Michael Carter

• HIV treatment preserves CD4 cell count during and after HCV therapy in co-infected patients

  Antiretroviral therapy helps preserve the CD4 cell counts of HIV-positive patients undergoing treatment for hepatitis C, Austrian investigators report in the June 15th edition of the Journal of Infectious Diseases. Treatment with anti-HIV drugs was also associated with ...

  03 May 2011 | Michael Carter

• Many South African patients not on ART are being lost to care

  Fewer than 50% of patients diagnosed with HIV in a district of rural South Africa who are not yet eligible for antiretroviral therapy have been retained in care, a study published in the online edition of the Journal of Acquired ...

  22 December 2010 | Michael Carter

• Low CD4 cell count associated with heart attack in patients with HIV

  A low CD4 cell count is associated with an increased risk of heart attack for patients with HIV, US investigators report in the online edition of the Journal of Acquired Immune Deficiency Syndromes. Even after taking into account traditional ...

  07 October 2010 | Michael Carter

• People with HIV with higher CD4 counts should not miss seasonal flu jabs

  HIV-positive patients with a CD4 cell count below 350 cells/mm3 have an impaired immune response to the seasonal influenza (flu) vaccine, Swiss investigators report in the September 10th edition of AIDS. They recommend that all HIV-positive patients should have an ...

  01 September 2010 | Michael Carter

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CD4 count news selected from other sources

• Predictive tool could cut HIV test costs

  A tool to monitor how HIV-positive patients respond to antiretroviral therapy (ART) could free up scarce personnel and laboratory resources in developing countries, according to an international team of researchers.

  08 May 2012 | SciDev Net

• Uganda - Boost for people living with HIV in western Ugandan district

  People in Kabarole, western Uganda look set to see an improvement in HIV diagnosis, care and treatment due to the arrival of a new CD4 count machine.

  20 January 2012 | Key Correspondents

• Rapid CD4 Testing Sharply Cuts HIV Patient Dropout Rate

  With the use of new rapid test kits -- which measure immune system health without having to send samples off site to laboratories and waiting for results -- researchers in Mozambique nearly doubled treatment enrollment and cut the number of patients lost almost in half.

  28 September 2011 | PBS Newshour

• HIV diagnostic maker Daktari drums up $1.8 million

  The Cambridge, Mass.-based developer of a point-of-care CD4 test raised $1.8 million from 32 unnamed investors, according to SEC document.

  07 November 2010 | Mass Device

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