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  • Enrollment complete for REMOX TB - global phase III clinical trial of new TB drugs

    The TB Alliance and its partners have completed patient enrollment in REMox TB, a global Phase III clinical trial, which may result in the registration of the first new drug approved for the treatment of drug-sensitive TB in nearly 50 years. REMox TB was designed to test whether a moxifloxacin-containing treatment regimen of just four months can cure drug-sensitive TB patients at rates that are non-inferior to those achieved with the standard six-month TB regimen.  In total, more than 1,900 patients were enrolled in REMox TB.

    02 February 2012 | TB Alliance
  • New Shorter Treatment for Latent TB Not Recommended for HIV+ People on ART

    Expert panels that put together the Department of Health and Human Services antiretroviral therapy (ART) guidelines have advised that the shorter and simpler combination regimen for latent tuberculosis (TB) recently recommended by the Centers for Disease Control and Prevention (CDC) is not suitable for people being treated for HIV.

    22 December 2011 | HIVandHepatitis.com
  • New Six-Way Agreement Among Pharmas and NGOs will Speed Development of TB Drug Combinations

    The Critical Path to TB Drug Regimens (CPTR) today announced an innovative agreement between AstraZeneca, Bayer, Sanofi, Tibotec, TB Alliance, and the World Health Organization to share information on tuberculosis (TB) compounds within their respective drug pipelines to quickly identify and work together to develop the most promising TB drug regimen, regardless of sponsor.

    10 November 2011 | Critical Path to TB Drug Regimens
  • High Drug Prices Hamper Drug-Resistant TB Treatment

    Access to treatment for drug-resistant tuberculosis (DR-TB) remains compromised, especially in developing countries, because too few pharmaceutical companies manufacture quality-assured drugs. Lack of competition has led to skyrocketing prices and this means that public health budgets are quickly spent.

    20 June 2011 | Inter Press Service
  • Tuberculosis Presents Double Threat to Women With HIV in Zambia

    Justina Banda, 44,says that because she is HIV-positive, it makes her extra prone to tuberculosis, TB. She has had TB three times, most recently last year. 

    02 June 2011 | Global Press Institute
  • TB study points to drugs to halt lung destruction

    Scientists have identified a key enzyme responsible for destroying lung tissue in tuberculosis (TB) and say the finding could lead swiftly to new treatments for the highly infectious disease.

    25 April 2011 | Reuters
  • Use of combination drug regimen for treating TB may represent an effective treatment option

    In patients with newly diagnosed tuberculosis, use of a combined 4-drug fixed-dose regimen was found to have comparable outcomes to drugs administered separately, according to a study in the April 13 issue of JAMA, a theme issue on infectious disease and immunology.

    12 April 2011 | Eurekalert Medicine & Health
  • ETHIOPIA: Reducing TB risk in Addis Ababa

    Health officials in Ethiopia's capital, Addis Ababa, are concerned about the spread of tuberculosis in the city's crowded public transport networks and tightly packed "DSTV [satellite television] houses" where ardent fans come to watch English and Spanish football.

    23 March 2011 | IRIN Plus News
  • A research agenda for TB

    Kevin M. DeCock, MD, director of the Center for Global Health at the Centers for Disease Control and Prevention (CDC), speaks with Science Speaks about the fight against TB.

    16 March 2011 | Science Speaks: HIV & TB News
  • Treatments for Recurring TB Infection Failing the Developing World, Study Finds

    The standard approach to re-treating tuberculosis (TB) in low and middle income settings is failing, according to research funded by the Wellcome Trust. In a study published March 15 in the open access journal PLoS Medicine, researchers call for improved access to rapid diagnostics for drug resistant TB, second-line TB treatment and antiretroviral HIV therapy.

    16 March 2011 | Science Daily
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