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  • Vaccines

    HIV vaccine researchers are still looking for a vaccine that would offer a significant degree of protection against HIV infection....

    From: Preventing HIV

    Information level Level 4
  • Vaccines

    The promise of an effective HIV vaccine has always been just over the horizon, but more than 20 years after the identification of HIV, vaccines...

    From: HIV transmission & testing

    Information level Level 4

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  • Potential New HIV Therapy Seen in Component of Immune Cells

    A research team led by Weill Cornell Medical College scientists has discovered a way to limit replication of the most common form of HIV at a key moment when the infection is just starting to develop. The study, published June 25 in Nature Communications, has shed light on a potential new element of human immunity against HIV-1 and could provide a powerful new strategy — perhaps as part of an HIV vaccine — to limit the severity of the disease.

    26 June 2015 | Weill Cornell Medical College
  • NIAID-funded HIV vaccine research generates key antibodies in animal models

    A trio of studies being published today in the journals Science and Cell describes advances toward the development of an HIV vaccine. The three study teams all demonstrated techniques for stimulating animal cells to produce antibodies that either could stop HIV from infecting human cells in the laboratory or had the potential to evolve into such antibodies. Each of the research teams received funding from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

    19 June 2015 | Eurekalert Medicine & Health
  • Sequential immunizations could be the key to HIV vaccine

    Scientists have thought for some time that multiple immunizations, each tailored to specific stages of the immune response, could be used to generate a special class of HIV-fighting antibodies, so-called broadly neutralizing antibodies. New findings provide the first evidence supporting this approach.

    19 June 2015 | Science Daily
  • French Based Biosantech Reports HIV Vaccine Safe

    Researchers from French-based Biosantech Company today reported that the company’s HIV vaccine candidate is not toxic to 48 HIV-positive patients enrolled in a double-blind study taking place in France. The data was presented at the International Conference on Retroviruses and Novel Drugs in suburban Chicago.

    17 June 2015 | PR Web
  • Some chimpanzees infected with AIDS virus may harbor protective, humanlike gene

    When Peter Parham’s postdoc first showed him data suggesting a gene in some wild chimpanzees infected with the AIDS virus closely resembled one that protects humans from HIV, he was skeptical.

    29 May 2015 | Science
  • HIV immunity: rare gene differences offer hope for treatment

    Seven years after the ‘Berlin patient’ was cured of HIV, scientists are looking to natural immunity through genetic variation to create vaccine and gene therapies

    12 May 2015 | The Guardian
  • Does Llama Blood Hold the Key to an HIV Vaccine?

    Previous research suggested that llamas given an experimental HIV vaccine produce virus-fighting antibodies that are smaller than those produced by humans. As a result, these smaller antibodies do a better job of latching onto the receptors in human cells where part of the virus lives. An HIV vaccine should target these receptors.

    11 May 2015 | Healthline
  • Improving the effect of HIV drugs by the use of a vaccine

    A vaccine containing a protein necessary for virus replication can boost an HIV-infected patient's immune system, according to clinical research published in the open-access journal Retrovirology. This boost can result in increased effectiveness of antiretroviral drugs.

    29 April 2015 | Eurekalert Inf Dis
  • An HIV Cure and a Vaccine within the Next 15 Years?

    Earlier this year, Bill Gates caused a ripple in the media by expressing optimism that a vaccine and a cure for HIV will become a reality within the next 15 years. From TAG’s perspective, Gates’s buoyancy does have some scientific basis—there have been encouraging signs of progress on both the vaccine and cure fronts in recent years—but the challenges that lie ahead must not be underestimated.

    13 April 2015 | Treatment Action Group
  • Broadly Neutralizing Antibody Suppresses HIV in Clinical Trial

    There is now intense interest in learning whether the blossoming array of broadly neutralizing antibodies (bNAbs) can be put to therapeutic and preventive use. A paper published yesterday in Nature describes encouraging results from a phase I trial involving the bNAb 3BNC117. Reflecting the level of interest in the topic, the paper has attracted extensive press coverage.

    10 April 2015 | TAG
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