Tuberculosis and HIV

Tuberculosis and HIV features

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  HIV and TB in Practice for nurses: Pregnancy and TB/HIV

  This article explains how to prevent and treat TB in pregnant women to protect both mother and child....

  From:  HIV & AIDS treatment in practice

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  HIV and TB in Practice for nurses: Drug-resistant TB

  This article summarises the key recommendations on the diagnosis and treatment of drug-resistant TB for nurses, and highlights examples of best practice in their care....

  From:  HIV & AIDS treatment in practice

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  HIV and TB in Practice for nurses: TB infection control

  This article provides practical information for nurses on TB infection control....

  From:  HIV & AIDS treatment in practice

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  HIV and TB in Practice for nurses: Starting ART for treatment and prevention in people with active TB and HIV

  This article provides information for nurses on starting HIV treatment for people with HIV and active TB....

  From:  HIV & AIDS treatment in practice

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  HIV and TB in Practice: Moving towards combination TB prevention

  This article looks at research on TB prevention, in particular the move towards combination TB prevention....

  From:  HIV & AIDS treatment in practice

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  HIV and TB in Practice for nurses: TB symptom screening and linking to diagnosis and care

  This edition looks at the practicalities of symptom screening and keeping track of patients during the diagnostic process....

  From:  HIV & AIDS treatment in practice

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  HIV and TB in Practice for nurses: active TB case finding

  The role of nurses and community health workers in the identification of TB in people living with HIV and in the wider community. ...

  From:  HIV & AIDS treatment in practice

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  HIV and TB in Practice for nurses: ART and TB prevention

  This edition is particularly intended for nurses and community health workers interested in TB and HIV....

  From:  HIV & AIDS treatment in practice

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  New laboratory tests to enhance TB diagnosis: Microscopy, LAM and Xpert MTB/RIF used as a drug resistance test

  The third in a series looking at the implications of new laboratory tests for TB diagnosis, particularly in people living with HIV. ...

  From:  HIV & AIDS treatment in practice

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  HIV and TB in Practice for nurses: non-communicable diseases, HIV and TB

  Conditions such as cancer, heart disease and diabetes in low- and middle-income countries, and awareness of these conditions in people living with HIV and/or TB. ...

  From:  HIV & AIDS treatment in practice

Tuberculosis and HIV in your own words

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  TB - my experiences

  This might sound odd, but I was really shocked when I became seriously ill because of HIV. I was even more shocked when it turned...

  From: In your own words

Tuberculosis and HIV news from aidsmap

• Steroids reduce mortality risk for people taking TB treatment

  Corticosteroid treatment is associated with a reduced risk of mortality for people taking tuberculosis (TB) therapy, results of a meta-analysis published in The Lancet Infectious Diseases show. Treatment with steroids was associated with a significant 17% reduction in mortality risk, ...

  24 March 2013 | Michael Carter

• Dosing of key TB drug rifampicin could go higher

  Rifampicin, a key drug in tuberculosis (TB) treatment, can be tolerated at much higher doses than used in current clinical practice – suggesting that much higher drug levels may lead to a more rapid treatment response, allowing the treatment ...

  07 March 2013 | Keith Alcorn

• Once-weekly continuation phase TB treatment equals standard of care

  A new two-drug combination of rifapentine and moxifloxacin can allow tuberculosis (TB) treatment to be taken once-weekly during the four-month continuation phase, Dr Amina Jindani of St George’s University Medical School, London, told the 20th Conference on Retroviruses and ...

  07 March 2013 | Keith Alcorn

• In resource-rich countries, migrants have a higher risk of progressing to AIDS in the first year of HIV therapy

  Rates of AIDS-defining illnesses in the first year of antiretroviral therapy are significantly higher among migrant than non-migrant populations in resource-rich countries, investigators report in the online edition of AIDS. The difference was mainly driven by higher rates of tuberculosis ...

  01 March 2013 | Michael Carter

• Results of TB vaccine trial give cause for optimism, say researchers

  Results of a trial have been praised for “providing hard evidence about protection against tuberculosis in human beings”. The MVA85A vaccine did not confer any additional protection against tuberculosis (TB) or infection with Mycobacterium tuberculosis to infants who had ...

  04 February 2013 | Michael Carter

• Hospital exposure the source of XDR-TB infections, underlining the need for adequate infection control

  Numerous hospital transmissions – rather than a single source – fuelled the outbreak of extensively drug-resistant tuberculosis (XDR-TB) at Tugela Ferry, South Africa, in 2005-06, research published in the online edition of the Journal of Infectious Diseases shows. Epidemiological ...

  30 January 2013 | Michael Carter

• Steep fall in incidence of TB among HIV-positive heterosexuals in the UK

  Incidence of tuberculosis (TB) among HIV-positive heterosexual people in England and Wales declined significantly between 2002 and 2010, investigators report in the online edition of AIDS. The fall is attributed to changes in the epidemiology of HIV in the ...

  15 January 2013 | Michael Carter

• Aggressive therapy for MDR-TB reduces risk of disease recurrence

  Aggressive treatment of multidrug-resistant tuberculosis (MDR-TB) significantly reduces the risk of disease recurrence, investigators report in the online edition of Clinical Infectious Diseases. Patients who received intensive therapy for at least 18 months after cure were 60% less ...

  31 December 2012 | Michael Carter

• Vitamin D deficiency increases risk of TB among people starting HIV therapy

  Vitamin D deficiency is associated with an increased risk of pulmonary tuberculosis (TB), oral thrush and wasting among people starting HIV therapy in Tanzania, investigators report in the online edition of the Journal of Infectious Diseases. People with vitamin D ...

  19 December 2012 | Michael Carter

• FDA Advisory Committee recommends accelerated approval of bedaquiline for drug-resistant TB

  Bedaquiline, the first agent in a new class of TB drug, has been recommended for accelerated approval by the Anti-Infective Drugs Advisory Committee of the United States Food and Drug Administration (FDA). The committee voted unanimously (18 to 0) ...

  03 December 2012 | Lesley Odendal

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Tuberculosis and HIV news selected from other sources

• India must address worrying stock out of tuberculosis drugs

  Indian government drug tender process leads to deadly delay in drug supply.

  17 June 2013 | MSF

• Directly Observed Therapy for Tuberculosis No Better than Self-Administration

  People who self-administered drugs to treat tuberculosis (TB) and those receiving directly observed therapy (DOT) had similar outcomes, according to a meta-analysis of 10 studies described in the July 2013 issue of Clinical Infectious Diseases.

  14 June 2013 | HIVandHepatitis.com

• Faces Of Drug-Resistant Tuberculosis

  Drug-resistant TB can now be found all over the planet, but some of the greatest concentrations of the disease are in the former Soviet Union. The tiny country of Moldova, which sits right at the edge of Eastern Europe and Central Asia, has one of the highest rates of MDR-TB in the world outside of Africa.

  05 June 2013 | NPR

• Uganda: Still long delays in diagnosing TB and HIV

  It still takes a long time for TB and HIV patients in Uganda to be properly diagnosed. As a result, many patients are infectious without knowing it themselves. These diagnostic delays, and also adherence to therapy, can be explained by a combination of social and health care related factors, such as a lack of awareness about the diseases, the sex of a patient and socioeconomic status.

  03 June 2013 | Netherlands Organisation for Scientific Research (NWO)

• Health Care for Immigrants Crumbling in Spain

  The death of a young Senegalese man from tuberculosis in Spain, following alleged lack of medical care, triggered a new outcry by civil society organisations against the law passed last year that excludes undocumented immigrants from the public health system except in emergencies.

  28 May 2013 | Inter Press Service

• US: TB programs affected by isoniazid shortage

  A shortage of isoniazid interfered with patient care and may contribute to the spread of tuberculosis in the United States, according to a report by the CDC. “Interruptions in the supply of second-line anti-TB medications have been ongoing in the United States for several years,” the researchers wrote in Morbidity and Mortality Weekly Report. “But since November 2012, TB control programs have experienced the first sustained generalized supply interruption of a first-line anti-TB medication.”

  24 May 2013 | Healio

• Book Review: The Plague That Refuses to Go Away

  Jasmine Grenier and Madhukar Pai from McGill University review “Spitting Blood: The History of Tuberculosis” by Helen Bynum.

  16 May 2013 | PLoS Blogs (blog)

• Lesotho to Expand HIV and Tuberculosis Programs

  [Global Fund]Maseru, Lesotho -The Global Fund to Fight AIDS, Tuberculosis and Malaria announced today that it is signing two grant agreements with the Ministry of Finance of Lesotho totaling US$17 million, to allow Lesotho to expand prevention and treatment of HIV and multidrug resistant tuberculosis (MDR-TB).

  09 May 2013 | AllAfrica

• The ongoing problem of tuberculosis in the UK

  The report of the All-Party Group on Global Tuberculosis gives grounds for optimism; although the task is huge it provides a coherent set of recommendations that can be taken on by a new public health body seeking to demonstrate its leadership and effectiveness. Successfully leading the strategy to eliminate tuberculosis in the UK should be an agreed metric to measure the performance of Public Health England.

  26 April 2013 | The Lancet (editorial)

• Most HIV patients in Papua co-infected with TB

  An official said Wednesday that around 60 percent of HIV-infected people in Papua are known to have also suffered from tuberculosis (TB) and that up to 40 percent of TB patients in the province are also HIV-positive.

  26 April 2013 | Jakarta Post

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