Treatment interruptions

Treatment interruptions features

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  Barriers to care: immigration removal centres and HIV

  Evidence has shown that a series of failings in immigration removal centres (IRCs) has compromised the continuity of care for people with HIV. Guest writer Daniel Lombard investigates. ...

  From:  HIV treatment update

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  The return of treatment interruptions?

  By Edwin J Bernard. Reporting by Gus Cairns. ...

  From:  HIV treatment update

Treatment interruptions in your own words

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  Finally undetectable!

  After almost 15 years of HIV, and six years of viral load testing, I heard on Thursday, June 21st 2001 that my viral load had...

  From:In your own words

Treatment interruptions news from aidsmap

• French researchers report 14 patients in 'remission' after controlling HIV for over 4 years off treatment

  Two weeks ago, the announcement that a baby had been ‘functionally cured’ of HIV disease with the use of very early antiretroviral therapy (ART) caused great excitement at the start of the Conference on Retroviruses and Opportunistic Infections (CROI 2013). ...

  16 March 2013 | Gus Cairns

• Unplanned treatment interruptions involve a greater risk of virological failure than missing occasional doses

  Unstructured treatment interruptions – rather than missed doses of medication – involve a greater risk of a detectable viral load, US research published in the online edition of AIDS suggests. Investigators analysed the results of 16 clinical trials, using ...

  04 May 2012 | Michael Carter

• Controversy regarding strategic treatment interruptions in young children who start ART during infancy

  Two studies generated conflicting data and rather mixed messages about whether it is safe or advisable to strategically interrupt treatment in children (STIC) who have initiated antiretroviral therapy (ART) during infancy – in order to reduce the challenges of ...

  09 March 2012 | Theo Smart

• Treatment breaks lead to fibrosis in HIV/HCV-co-infected patients

  Interrupting HIV therapy is associated with the progression of liver damage in patients co-infected with HIV and hepatitis C, Canadian investigators report in the online edition of AIDS. Taking a break from antiretroviral therapy more than doubled the risk ...

  07 April 2011 | Michael Carter

• Treatment interruptions explain higher HIV viral load in patients with depression and those who use stimulants

  Inconsistent use of antiretroviral therapy is the main explanation for the higher viral loads observed in HIV-positive patients who are depressed or who use stimulant drugs, US investigators report in the February 1st edition of the Journal of Acquired ...

  08 February 2011 | Michael Carter

• Breaks from HIV therapy still associated with poorer outcomes 8 years later

  HIV-positive patients who take breaks from their antiretroviral therapy have poorer increases in their CD4 cell count, are more likely to develop HIV-related illness, and have a higher risk of death than individuals who take continuous treatment, and these ...

  18 January 2011 | Michael Carter

• Even with antiretroviral treatment, patients with HIV still have markers indicating increased risk of heart disease and kidney problems

  Key biomarkers associated with an increased risk of serious illnesses such as heart disease and kidney dysfunction are elevated in patients with HIV, even when they are taking HIV treatment, a study published in the June ...

  19 May 2010 | Michael Carter

• Thrombocytopenia associated with treatment interruptions: HIV replication a cause

  A quarter of patients interrupting antiretroviral therapy developed thrombocytopenia, French investigators report in the December 15th edition of the Journal of Acquired Immune Deficiency Syndromes. “Even a short treatment interruption of a few weeks could lead to ...

  12 January 2010 | Michael Carter

• ‘Drug holidays’ best predictor of treatment failure, adherence studies find

  Failure to take every dose on time is not a good guide to whether patients will fail their therapy, according to studies from several countries presented at the European AIDS Conference. A better guide, and one ...

  23 November 2009 | Gus Cairns

• Early treatment and interruption makes no difference to disease progression, study finds

  The largest study yet done on the whether immediate antiretroviral therapy (ART) may benefit people with recent HIV infection has found that immediate treatment followed by treatment interruption produced no reduction in the subsequent viral load ...

  04 September 2009 | Gus Cairns

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Treatment interruptions news selected from other sources

• Post-Treatment HIV-1 Controllers with a Long-Term Virological Remission after the Interruption of Early Initiated Antiretroviral Therapy ANRS VISCONTI Study

  Our results show that early and prolonged cART may allow some individuals with a rather unfavorable background to achieve long-term infection control and may have important implications in the search for a functional HIV cure.

  15 March 2013 | PLoS Pathogens

• Malawi: Malawi's Never-Ending Drug Shortage Problem

  Malawi is again experiencing a crisis in the delivery of essential medicines, with understaffed clinics and erratic drug supplies preventing many dangerously ill patients from accessing treatment.

  20 February 2013 | AllAfrica

• Pegylated interferon may maintain HIV suppression and reduce viral DNA integration

  Adding pegylated interferon alfa to antiretroviral therapy (ART) for HIV may help some people control viral replication when they interrupt treatment, according to a small study reported at this year's Conference on Retroviruses and Opportunistic Infections (CROI 2012) and published in the October 26, 2012, advance online edition of the Journal of Infectious Diseases.

  12 November 2012 | HIVandHepatitis.com

• Brief Treatment Interruptions for Cure Studies Are Safe, Well-Tolerated

  Short treatment interruptions of HIV antiretroviral regimens are both safe and well-tolerated, which is good news for scientists pursuing functional cures. 

  05 November 2012 | AIDSMeds

• Ivory Coast doctor warns hundreds more will die if they can't get HIV treatment

  “The situation is very serious. Our programmes are suspended because of the violence. We are very worried that although some HIV treatment is available, supplies will run out in the next 2-3 weeks unless new supplies of medicines are able to be got into the country."

  06 April 2011 | Reuters AlertNet

• Stigma forces many to leave ART midway: Expert

  HIV patients on antiretroviral treatment (ART) leaving drug-course midway has become one of the biggest concerns in India.

  29 March 2011 | Times of India

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