News and information about basic science that may lead researchers to develop a cure for HIV – studies of the latent viral reservoir, shock and kill approaches, gene therapies, immune modulators therapeutic vaccines, broadly neutralizing antibodies and so on.

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  • Italy's therapeutic AIDS vaccine shows drastic reduction of HIV virus reservoirs: study

    Clinical trials of an Italian therapeutic vaccine against AIDS showed a drastic reduction of virus reservoirs in treated patients, Italian researchers said on Wednesday.

    14 March 2019 | Xinhua
  • CROI 2019: Will the “Düsseldorf patient” make three — further propelling cure research?

    Five years after a stem cell transplant with the same critical factor as those received by the Berlin patient and the London patient, and four months after stopping antiretroviral treatment, a Düsseldorf man remains virally suppressed

    12 March 2019 | Science Speaks
  • Anthony Fauci: Physicians cured a man of HIV, but that's not our best shot at fighting AIDS

    The Berlin and London patients give important insights for HIV researchers, and a cure for HIV is an aspiration we continue to pursue. But the end of the epidemic - the reduction of new HIV infections and HIV-related deaths to very low levels - is within our reach even without a cure.

    12 March 2019 | Sydney Morning Herald
  • What You Need to Know About the Second Person Likely Cured of HIV

    Interview with Richard Jefferys, the Basic Science, Vaccines, and Cure Project Director of Treatment Action Group, about the significance of the second person seemingly cured of HIV, what both community members and journalists should know about this study, and how HIV cure research stories in the mainstream press can create false hope for people living with HIV.

    11 March 2019 | The Body Pro
  • When Undetectable Is Unachievable: Study Offers Insights into HIV Persistence

    Rarely, people living with HIV are unable to maintain an undetectable viral load despite strict adherence to daily ART. New NIAID-funded research suggests that this sometimes can occur when a single cell from the HIV reservoir—the population of long-lived HIV-infected cells that ART cannot eradicate—multiplies to create many identical cells that produce enough virus to be detected by standard viral load tests.

    11 March 2019 | National Institute of Allergy and Infectious Diseases
  • This is Not A Cure for My H.I.V.

    The news about a second person who may be free of the infection is a distraction from the work we need to keep focusing on.

    11 March 2019 | New York Times
  • An H.I.V. Cure: Answers to 4 Key Questions

    Translating the latest success against the AIDS virus into a practical treatment will take years — if it happens at all. Here are answers to some of the most pressing questions raised by the news.

    11 March 2019 | New York Times
  • Has a second person with HIV been cured?

    “This is a big deal,” says Sharon Lewin, who heads the Peter Doherty Institute for Infection and Immunity in Melbourne, Australia. “It tells us that Timothy Brown wasn’t a one-off.” Although the interventions that the two patients received could only be used on a tiny fraction of the 37 million HIV-infected people worldwide, their stories point to cure strategies that could be more widely applicable.

    06 March 2019 | Science Magazine
  • Using anti-cancer immunotherapy to fight HIV

    Researchers at the University of Montreal Hospital Research Centre (CRCHUM) have shown that immunotherapy treatments against cancer could reduce the amount of virus that persists in people on triple therapy. In a study published in the journal Nature Communications, they show, in the cells of people living with HIV, how these therapies reveal the virus - until now hidden in the hollows of infected cells - to the immune system.

    20 February 2019 | Eurekalert Medicine & Health
  • HIV-1 protein suppresses immune response more broadly than thought

    Scientists have revealed how a protein produced by HIV-1 plays a broader role in suppressing the immune system's response to infection than previously thought.

    06 February 2019 | Eurekalert Inf Dis
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