News and information about basic science that may lead researchers to develop a cure for HIV – studies of the latent viral reservoir, shock and kill approaches, gene therapies, immune modulators therapeutic vaccines, broadly neutralizing antibodies and so on.

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  • HIV protein function that slows migration of T cells also improves viral survival

    A study from a Massachusetts General Hospital (MGH) research team has identified the specific function of a protein found in HIV and related viruses that appears to slow down viral spread in the earliest stages of infection. But they also found that, after initially slowing down the spread of infection, that function may help the virus survive later on by evading the immune response.

    15 January 2019 | Medical Xpress
  • Larger HIV Reservoirs Found in Those with Clade B Subtype

    A study team led by investigators from Simon Fraser University in Canada have made a key discovery on how viral factors, such as HIV subtypes, impact the size of the virus reservoirs in individuals with HIV.

    15 January 2019 | Contagionlive.com
  • The Road Ahead for HIV Cure Research

    Today, with better understanding of the complex task at hand, cure researchers are investigating multiple avenues and taking the long view.

    08 January 2019 | Poz
  • HIV Establishes Reservoir Within Three Days in Monkeys

    Beginning six months of treatment within two days following infection prevented viral rebound in at least some animals in a recent study.

    01 January 2019 | Poz
  • AIDS - an approach for targeting HIV reservoirs

    (Institut Pasteur) Current HIV treatments need to be taken for life by those infected as antiretroviral therapy is unable to eliminate viral reservoirs lurking in immune cells. Institut Pasteur scientists have identified the characteristics of CD4 T lymphocytes that are preferentially infected by the virus. Thanks to metabolic activity inhibitors, the researchers have managed to destroy these infected cells, or 'reservoirs', ex vivo. Their findings were published in the journal Cell Metabolism on Dec. 20, 2018.

    20 December 2018 | Eurekalert Medicine & Health
  • The HIV/AIDS Activists Transformed Genetic Engineering

    Over the past decade, a group of HIV activists has helped pioneer gene therapy.

    20 December 2018 | The Atlantic
  • Trump quietly shuts down HIV cure research to appease the religious right

    Scientists are speaking out against a directive by the Trump administration that has shut down research into a cure for HIV. A scientist who was supposed to supply mice that have been modified with human fetal tissue for an HIV study emailed researchers that the Department of Health and Human Services (HHS) “has directed me to discontinue procuring fetal tissue.”

    12 December 2018 | LGBTQ Nation
  • UCSF HIV Lab Planning to Close

    The facility is the second to have a federal contract involving fetal tissue research cancelled.

    06 December 2018 | The Scientist
  • Open letter from Chinese HIV professionals on human genome editing

    As Chinese professionals engaged in HIV research and prevention, we strongly oppose genome editing on healthy human germline cells and embryos for reproductive purposes and HIV prevention.

    05 December 2018 | The Lancet
  • Needles in a haystack: the quest for bnAbs

    HIV induces antibody responses in infected individuals, but only a few of these individuals manage to produce antibodies that are capable of viral neutralization—and even fewer produce antibodies that can neutralize different strains of HIV.

    01 December 2018 | Nature
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