Findings presented at the 21st International AIDS Conference (AIDS 2016) in Durban, South Africa, suggest that combining ART with an immune-enhancing treatment may destabilize viral reservoirs in macaques infected with simian immunodeficiency virus (SIV), the monkey equivalent of HIV.
21 July 2016 | NIAID
Investigators from the National Institutes of Health have discovered that cells from HIV-infected people whose virus is suppressed with treatment harbor defective HIV DNA that can nevertheless be transcribed into a template for producing HIV-related proteins. This finding may affect scientists’ understanding of the long-term effects of HIV infection and what a cure would require.
18 July 2016 | NIAID
History suggests that finding a "classic" cure for HIV -- clearing the virus from the body -- is going to be a tough chore, a top U.S. official said here. On the other hand, a less aspirational goal -- that of achieving sustained remissions from the virus -- looks closer to hand in the current state of medical science, according to Anthony Fauci, MD, director of the NIH's National Institute of Allergy and Infectious Diseases.
17 July 2016 | MedPage Today
“HIV cure research became a scientific reality with the launch of the first IAS Global Scientific Strategy: Towards an HIV Cure at AIDS 2012,” noted IAS President Chris Beyrer. “Today, HIV cure research has come into its own as a top HIV research priority, marked by significant advances in our understanding of the scientific challenges and opportunities, more cure-focused research collaborations, and a new optimism that a cure or sustainable remission for HIV is feasible.”
16 July 2016 | AIDS 2016
UK scientists may have found a way to destroy HIV's last refuge. A study by Oxford University has confirmed that a treatment developed by a British company can remove the virus in its chosen hiding place, in laboratory conditions, offering hope of a viable treatment.
14 July 2016 | Eurekalert
The National Institutes of Health has awarded approximately $30 million in annual funding over the next five years to six research collaborations working to advance basic medical science toward an HIV cure.
14 July 2016 | National Institutes of Health
We all got really excited a few weeks ago when researchers announced they'd removed HIV from human immune cells using new gene-editing technology called CRISPR/Cas-9, or 'CRISPR' for short, which works like a pair of molecular scissors to cut and paste DNA. As far as we know, that specific result is holding up just fine, but a separate study has now revealed that, worryingly, HIV can evolve to survive CRISPR attacks in just two weeks. Even worse, the attack itself could actually be introducing mutations that make the virus stronger.
11 April 2016 | ScienceAlert
A series of media outlets have erroneously reported that scientists may be just three years away from developing a cure for HIV. This false claim traces to an article published in the United Kingdom’s The Telegraph concerning researchers who recently succeeded in editing HIV’s genetic code out of immune cells in a laboratory setting.
06 April 2016 | Poz
A specialised gene editing system designed by scientists at the Lewis Katz School of Medicine at Temple University is paving the way to an eventual cure for patients infected with HIV. In a study published online this month in the Nature journal, Scientific Reports, the researchers show that they can both effectively and safely eliminate the virus from the DNA of human cells grown in culture.
23 March 2016 | Temple University
An immune-enhancing treatment can push SIV (simian immunodeficiency virus) out of its hideouts in infected monkeys that have the virus controlled with drugs, scientists at Yerkes National Primate Research Center, Emory University report.
26 February 2016 | Emory Health Sciences