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  • Future of HIV cure research points to combination approach

    The next five years of HIV research should shift gears from the classic single-therapy development model to moving directly from in vitro studies to combination therapy trials, authors argue in a new paper published online today.

    01 October 2015 | US Military HIV Research Program press release
  • DART protein shows potential as shock-and-kill strategy against HIV

    A unique molecule developed at Duke Medicine, the University of North Carolina at Chapel Hill and MacroGenics, Inc., is able to bind HIV-infected cells to the immune system's killer T cells. It could become a key part of a shock-and-kill strategy being developed in the hope of one day clearing HIV infection.

    29 September 2015 | Medical News Today
  • Fat Tissue May Be Another Part of HIV Reservoir

    In addition to possibly being a component of the HIV reservoir, fat tissue may also be a source of harmful chronic inflammation among those living with the virus. Publishing their findings in PLOS Pathogens, researchers studied adipose (fat) tissue in both macaque monkeys infected with SIV, HIV’s simian cousin, as well as HIV-positive humans who underwent elective abdominal surgery.

    28 September 2015 | Aidsmeds
  • Sangamo BioSciences Reports Updated Clinical Data from ZFP Therapeutic® Program for HIV/AIDS

    Sangamo BioSciences, Inc. presented data demonstrating sustained functional control of viral load in the absence of antiretroviral drugs (ART) in two of three HIV-infected subjects treated in Cohort 3* of its Phase 1/2 study (SB-728-1101) of its ZFP Therapeutic (SB-728-T) for the treatment of HIV/AIDS. The data, which led to expanded enrollment of this Cohort, were presented at the 2015 Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC) in San Diego from September 17-21.

    22 September 2015 | Sangamo press release
  • Romidepsin can reverse HIV latency in patients on long-term ART without compromising T-cell function

    HIV latency depends on the activity of proteins from the human host called histone deacetylases, and previous work has shown that HDAC inhibitors can disrupt HIV latency. This study reports results from a clinical trial of an HDAC inhibitor that had shown potential in preclinical studies and answers open questions about the potential use of these drugs in strategies to eliminate HIV from the body.

    21 September 2015 | Science Daily
  • Cancer drug promises to break down barrier to HIV cure

    Researchers have found a promising way of kicking the AIDS virus out of its hiding place in infected cells, potentially removing the main obstacle to curing HIV.

    21 September 2015 | The Conversation
  • U.S. Survey on Willingness to Participate in HIV Cure-Related Research: Your Opinion Matters (US readers only)

    There has been an increase in HIV cure research in the recent years. We would like to find out how people living with HIV (or potential HIV cure research volunteers) perceive HIV cure research, including their willingness to participate in HIV cure studies. We would also like to find out what would help implement HIV cure studies. Your answers to these questions will be kept strictly confidential.

    16 September 2015 | University of North Carolina
  • HIV Hiding in the Body Unveiled with a PET Scan

    One of the reasons why it's so hard to cure HIV and AIDS is because of the fact that the HIV virus has the capacity to hide inside the victim's body. However a new scanning technique shows promise making it easier for researchers to pinpoint HIV hiding in the body.

    08 September 2015 | Crossmap
  • After Curing Hepatitis C, Gilead Works to Vanquish More Viruses

    Gilead Sciences Inc., basking in the success of its cure for hepatitis C, is setting ambitious goals to vanquish two other major viral scourges: HIV and hepatitis B.

    19 August 2015 | Bloomberg
  • HIV cure research today: Gene therapy, molecular scissors and Where’s Waldo

    From across the country, HIV experts and cancer researchers who have devoted their careers to improving stem cell transplants came together at Fred Hutchinson Cancer Research Center Thursday and Friday. Their goal? To talk about how to translate the world’s only known HIV cure into a cure or long-term remission that is less risky, less costly and broadly applicable to the millions worldwide now living with the virus.

    18 August 2015 | Fred Hutch News Service
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