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  • After Curing Hepatitis C, Gilead Works to Vanquish More Viruses

    Gilead Sciences Inc., basking in the success of its cure for hepatitis C, is setting ambitious goals to vanquish two other major viral scourges: HIV and hepatitis B.

    19 August 2015 | Bloomberg
  • HIV cure research today: Gene therapy, molecular scissors and Where’s Waldo

    From across the country, HIV experts and cancer researchers who have devoted their careers to improving stem cell transplants came together at Fred Hutchinson Cancer Research Center Thursday and Friday. Their goal? To talk about how to translate the world’s only known HIV cure into a cure or long-term remission that is less risky, less costly and broadly applicable to the millions worldwide now living with the virus.

    18 August 2015 | Fred Hutch News Service
  • HIV cure: From pipe dream to promising

    A longtime activist offers cautious optimism on the eve of HIV cure conference.

    14 August 2015 | Fred Hutch News Service
  • HIV grows despite treatment, study finds

    A study by the University’s Institute of Infection and Global Health measured the levels of integrated HIV in the CD4 cells of patients undergoing uninterrupted treatment for up to 14 years, comparing patients receiving treatment for different lengths of time. The researchers discovered that the amount of HIV found to be integrated in the CD4 cells was undiminished from year 1 to year 14.

    07 August 2015 | University of Liverpool press release
  • Waking up HIV: Two compounds show great potential to rouse latent virus

    Researchers at UC Davis have identified a compound that activates latent HIV, offering the tantalizing possibility that the virus can be flushed out of the silent reservoirs and fully cured. Even better, the compound (PEP005) is already approved by the FDA. The study was published in the journal PLoS Pathogens.

    04 August 2015 | UC Davis press release
  • 'Molecular microscope' finds hidden AIDS virus in the body

    Researchers have developed a sophisticated new probe that detects HIV’s hiding places inside and outside of cells. Insights from this high-powered molecular microscope, revealed at an international AIDS conference last week, may clarify critical questions about HIV persistence and, ultimately, about how to rid the body of the virus.

    27 July 2015 | Science
  • Bold goal of stopping HIV is motivating great science

    The massive challenge of finding an HIV vaccine has unleashed stunning creativity in laboratories all over the world. While we work toward the long-term goal of a vaccine, we are also pulling in partners from many sectors to improve prevention, treatment, and access to options in the short term.

    13 July 2015 | Devex
  • Scripps Research Institute-Designed Drug Candidate Significantly Reduces HIV Reactivation Rate

    HIV-infected patients remain on antiretroviral therapy for life because the virus survives over the long-term in infected dormant cells. Interruption of current types of antiretroviral therapy results in a rebound of the virus and clinical progression to AIDS. But now, scientists from the Florida campus of The Scripps Research Institute (TSRI) have shown that, unlike other antiretroviral therapies, a natural compound called Cortistatin A reduces residual levels of virus from these infected dormant cells, establishing a near-permanent state of latency and greatly diminishing the virus’ capacity for reactivation.

    11 July 2015 | Scripps Research Institute
  • Risks vs rewards: why people with HIV volunteer for 'cure' research

    A recent survey of people living with HIV in the United Kingdom found that more than half would participate in a clinical study to develop a cure for HIV, despite this posing a risk to their health. Why would someone choose to do this?

    24 June 2015 | The Conversation
  • Perspectives on Post-Treatment Control of HIV

    Several recent papers offer perspectives on the possibility of achieving post-treatment control of HIV replication by starting antiretroviral therapy (ART) during acute infection.

    03 June 2015 | The Body
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