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  • Early treatment reduces viral reservoirs but does not prevent rebound

    Antiretroviral therapy started during the first several days after infection limited dissemination of an HIV-like virus throughout the body and establishment of cellular and tissue reservoirs in monkeys, but it did not prevent the virus from coming back after ...

    21 March 2014 | Liz Highleyman
  • Early antiretroviral therapy may limit gut damage and immune activation

    Starting antiretroviral therapy (ART) at the earliest stage of HIV infection can help prevent immune cell dysregulation that contributes to destruction of the gut lining and promotes systemic immune over-activation, according to a study presented at the 21st Conference ...

    20 March 2014 | Liz Highleyman
  • Protected T-cells persist and proliferate in HIV gene therapy study

    Genetically modified CD4 T-cells lacking CCR5 co-receptors reach high levels in the body and are resistant to HIV infection, potentially enabling people to maintain a low viral load while off antiretroviral therapy (ART), according to the latest reports from ...

    07 March 2014 | Liz Highleyman
  • The 'Boston patients' experience HIV rebound after stem cell transplants

    HIV has re-emerged in two Boston men who underwent experimental antiretroviral therapy interruption after receiving bone marrow stem cell transplants for cancer treatment, Timothy Henrich reported yesterday at the 21st Conference on Retroviruses and Opportunistic Infections (CROI) in Boston. These ...

    07 March 2014 | Liz Highleyman
  • A cure may need multiple components, workshop delegates hear

    Delegates at the community cure workshop in advance of the 21st Conference on Retroviruses and Opportunistic Infections (CROI 2014) in Boston might have been in a less hopeful frame of mind than they had been seven months previously when, ...

    04 March 2014 | Gus Cairns
  • HIV may be becoming less fit as it adapts to the immune system

    HIV, at least in some parts of the world, may be developing a lower replicative capacity as it adapts to variations in the human immune system, studies in southern Africa and elsewhere suggest. Philip Goulder of the University of Oxford ...

    08 November 2013 | Gus Cairns
  • Experts debate whether HIV cure is 'hype or hope'

    Is a functional cure for HIV feasible within the foreseeable future or is it a hopeless quest robbing resources from more practical approaches to improve the lives of people living with HIV? This question was the crux of ...

    17 October 2013 | Liz Highleyman
  • Vaccine trials – where next?

    New efficacy trials of HIV vaccines based on what has been learned in the RV144 vaccine trial in Thailand and the HVTN 505 trial in the US are going forward in heterosexual people in South Africa and will probably also ...

    16 October 2013 | Gus Cairns
  • Researchers see further positive results with herpes virus-based vaccines in monkeys

    One of the biggest news stories at the AIDS Vaccine 2013 conference was the groundbreaking experiment in which half of a group of monkeys given a candidate monkey-HIV vaccine appeared to lose all trace of viral infection. This vaccine ...

    09 October 2013 | Gus Cairns
  • HIV vaccine conference opens in most promising research atmosphere for years

    The 13th – and last – AIDS Vaccine 2013 Conference opened today in Barcelona in an atmosphere of low-key excitement, with recent research findings to be presented at the conference, signposting new pathways towards the ultimate goal of a preventive ...

    07 October 2013 | Gus Cairns
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The search for a cure news selected from other sources

  • Transplant Drugs May Fight HIV Reservoir

    Immunosuppressant drugs used to prevent rejction of transplanted organs may combat the HIV reservoir.

    14 April 2014 | AIDSMeds
  • Man Who Began HIV Treatment 5 Days In Appears Virus-Free

    A man who contracted HIV about five days before starting PrEP and 12 days before starting HIV treatment appears virus-free several months later.

    25 March 2014 | AIDSMeds
  • Gilead Following Multiple Paths Toward HIV “Functional Cure”

    Gilead has been exploring a range of different strategies to block the HIV virus from surging back after treatment, and has been lining up research partnerships that include other drug developers, academic researchers, and government agencies.

    25 March 2014 | Xconomy
  • Drugs fail to reawaken dormant HIV infection

    Scientists at Johns Hopkins report that compounds they hoped would 'wake up' dormant reservoirs of HIV inside immune system T cells -- a strategy designed to reverse latency and make the cells vulnerable to destruction -- have failed to do so in laboratory tests of such white blood cells taken directly from patients infected with HIV.

    24 March 2014 | Eurekalert Medicine & Health
  • HIV Cure Research at CROI 2014

    A round-up of cure research at the 21st Conference on Retroviruses and Opportunistic Infections.

    17 March 2014 | BETA blog
  • Reports of a Second Baby Possibly Cured of HIV: Uncertainty Remains

    The media is awash with stories relating to a conference presentation by Deborah Persaud from Johns Hopkins University, in which she described the case of an HIV-infected baby who was treated within four hours of birth and now shows no detectable HIV after nine months of follow up.

    10 March 2014 | TAG Basic Science Blog
  • HIV disappears in 'Los Angeles baby,' doctors say

    The girl, who was born in April and is being referred to as the "Los Angeles baby," remains on three standard HIV medications. Because of this, doctors cannot say for certain yet whether the infant is cured or whether the disease has gone into remission.

    06 March 2014 | Los Angeles Times
  • HIV gene therapy using GM cells hailed a success after trial

    Radical treatment helps patients' defences against virus by replacing immune cells with genetically modified versions.

    05 March 2014 | The Guardian
  • A Second Baby Born With HIV Is Now Apparently HIV Negative

    A second baby born with HIV has no evidence of the virus in her body following an aggressive treatment regimen given shortly after birth.

    05 March 2014 | AIDSMeds
  • Can San Francisco Become the First AIDS-Free City?

    The city that was once the deadly AIDS epicenter of the world is now striving to be AIDS-free. What does that mean, and why is San Francisco poised to achieve this goal the way no other American city could?

    05 March 2014 | The Advocate
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