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TB’s interaction with HIV

There is some evidence that having active TB leads to a fall in CD4 cell count and a rise in viral load. This means the effect of HIV may be worse unless anti-HIV drugs are given and the TB is treated.

However, people with HIV who have had TB and been successfully treated are just as likely to benefit from HIV treatment, experiencing the same fall in viral load and increase in CD4 cell count, as HIV-positive people who have never had the disease, and living just as long.

CD4 cell count and viral load are the key indicators of the effect HIV is having on the immune system and should be monitored regularly.  If you’re not sure what they are or what they mean, NAM produces a booklet called Viral load & CD4, which should answer your questions. Contact us for a free copy.

This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.