Pregnancy

The safety of saquinavir (Invirase) in pregnancy is currently being investigated. Animal studies and observational studies of pregnant women taking saquinavir have shown no evidence of harmful effects to foetuses or mothers.1 2

References

  1. Zorrilla CD et al. Clinical response, safety, and tolerabiliy to saquinavir-SCG with low-dose ritonavir boosting in combination with zidovudine and lamivudine in HIV-1 infected pregnant women: preliminary results of PACTG 386. Tenth Conference on Retroviruses and Opportunistic Infections, Boston, abstract 887, 2003
  2. Vithayasai V et al. Safety and efficacy of saquinavir-soft gelatin capsules + zidovudine + optional lamivudine in pregnancy and prevention of vertical HIV transmission. Seventh European Conference on Clinical Aspects and Treatment of HIV Infection, Lisbon, abstract 1215, 1999
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