PEP

PEP in your own words

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  Needlestick injury

  I am an HIV-positive doctor. I was infected courtesy of a lapse in concentration and a needlestick injury at work. The prescribed dual post-exposure prophylaxis (PEP) was taken for one...

  From:In your own words

PEP news from aidsmap

• Awareness rises following PEP communications

  Gay men’s awareness of HIV post-exposure prophylaxis (PEP) significantly improved in Western Australia, following implementation of a communications strategy, according to a study recently published in BMC Public Health. The study is of interest as research on the impact ...

  14 January 2013 | Roger Pebody

• Spanish researchers urge more awareness campaigns on PEP

  Only a third of gay men and one in six heterosexual people who came forward for a rapid HIV community testing programme were aware of post-exposure prophylaxis (PEP), a Spanish study has found. Post-exposure prophylaxis (PEP) needs to be distinguished ...

  02 November 2012 | Gus Cairns

• Poor adherence to HIV PEP after sexual assault

  Adherence to HIV post-exposure prophylaxis (PEP) among victims of sexual assault is poor, according to the results of a meta-analysis and systematic literature review published in Sexually Transmitted Infections. Approximately 40% of patients did not return for follow-up appointments. ...

  16 March 2012 | Michael Carter

• Raltegravir/Truvada HIV PEP regimen well tolerated with no infections after its use

  Raltegravir could have a “useful” role in HIV post-exposure prophylaxis, according to investigators from the US writing in the online edition of the Journal of Acquired Immune Deficiency Syndromes. Doctors in Boston, Massachusetts, prescribed a post-exposure prophylaxis (PEP) regimen of ...

  31 January 2012 | Michael Carter

• PEP guidelines for the UK revised to take account of undetectable viral load

  New UK guidelines for the use of post-exposure prophylaxis (PEP) following sexual exposure have been published in the December issue of the International Journal of STD and AIDS. The guidelines are notable for no longer recommending that PEP is provided ...

  21 December 2011 | Roger Pebody

• Ongoing risk behaviour likely cause of high HIV incidence rate among gay men treated with PEP

  HIV incidence is high among gay men who use post-exposure prophylaxis (PEP), investigators from Amsterdam report in the online edition of AIDS. Overall, users of PEP were almost four times more likely to become infected with HIV than gay ...

  20 December 2011 | Michael Carter

• 'Less education' associated with PrEP and PEP use: only one in five gay men yet aware of PrEP

  A survey (Mansergh) of 454 HIV-negative gay men in four US cities (New York, Los Angeles, Chicago and San Francisco) has found that men with lower educational attainment (high school only) were more likely to use antiretrovirals informally for HIV ...

  16 September 2011 | Gus Cairns

• Intensive and targeted PEP counselling leads to less risky sex afterwards, fewer HIV infections

  People at higher risk of HIV infection who take post-exposure prophylaxis benefit from an intensive programme of risk reduction counselling, American researchers report in the 1 July issue of Clinical Infectious Diseases. Participants made durable changes to their sexual ...

  21 June 2011 | Roger Pebody

• One dose of raltegravir gel three hours after sex might prevent HIV infection

  A study presented at the 18th Conference on Retroviruses and Opportunistic Infections (CROI) in Boston has found that a single dose of a microbicide gel containing the integrase inhibitor raltegravir (Isentress), given three hours after vaginal exposure to ...

  01 March 2011 | Gus Cairns

• Mass rape and HIV in conflict-affected countries: despite relatively low incidence, researchers stress urgency of interventions for thousands of women in need

  Mass rape during armed conflict may account for several thousand new cases of HIV per year in sub-Saharan Africa, according to an article in the journal AIDS. Researchers drew this conclusion after analysing data from seven conflict-affected countries with high HIV prevalence: ...

  30 September 2010 | Kelly Safreed-Harmon

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PEP news selected from other sources

• Postexposure Prophylaxis: Dealing With Old Guidelines

  The patient responded, “With all due respect to the guidelines, in the current era when there are increasingly well-tolerated medications, why would you use a regimen that included only 2 NRTIs without a third drug in any setting where there is a risk of HIV transmission?”

  13 March 2013 | Clinical Care Options (requires registration)

• Australia: Second man denied PEP from hospital

  Another gay man has come forward claiming he was unable to access HIV-preventative medication from his local health centre due to ignorance of proper procedure from medical staff.

  23 January 2013 | Sydney Star Observer

• New report: evaluating HIV treatment as prevention in the European context

  The report concludes that antiretroviral treatment has well-documented benefits for reducing the transmission of HIV, and has had a major impact on reducing HIV acquisition among children born to HIV positive mothers. However, the policy of treatment as prevention cannot be universally applied to all persons diagnosed with HIV without understanding whether there is a benefit for the individual’s health.

  07 June 2012 | European Centre for Disease Prevention and Control (ECDC) press release

• Post-Exposure Prophylaxis, the World’s Most Outdated HIV Guidelines, and What To Do About Them

  Every time I cover HIV prevention in a lecture, it’s always kind of embarrassing to cite the “official” post-exposure prophylaxis (PEP) guidelines.

  06 March 2012 | Journal Watch

• KENYA: Sexual violence still a major urban threat

  Reports of gender-based violence are on the rise in Kenya's cities, and experts say the police must improve their handling of cases of sexual assault to build public trust in the security and justice systems. 

  26 October 2011 | IRIN Plus News

• Brown signs bill letting California minors get STD vaccine

  Gov. Jerry Brown has waded into the national debate over child vaccinations for sexually transmitted diseases, signing into law a bill allowing children as young as 12 to get vaccinated without their parents' consent.

  09 October 2011 | Sacramento Bee

• Michigan tells poor patients needing PEP: pay for it yourselves

  The Michigan Department of Community Health says that Michigan residents without insurance or cash to pay the $1,000 tab for a one month prescription to prevent infection with HIV after an exposure are on their own in finding ways to pay for the drugs.

  23 June 2011 | Michigan Messenger

• South Africa: Police failing rape victims

  "The police service routinely fails to follow correct procedures such as informing victims that they have the right to post-exposure prophylaxis to prevent HIV transmission, and also to demand that the suspect be tested for HIV," TLAC spokesperson Lisa Vetten said in a statement.

  22 March 2011 | News 24

• Ireland: Doctor who contracted HIV settles High Court action

  A DOCTOR WHO contracted HIV while performing his duties as a surgeon has settled his High Court case against the hospital where he had worked, the HSE, and the state.

  27 January 2011 | thejournal.ie

• India: Accidental exposure to HIV gets needed attention

  The Delhi government has started a first-of-its-kind initiative to train healthcare professionals in government hospitals on accidental exposure to HIV while treating patients, or Post Exposure Prophylaxis (PEP).

  24 January 2011 | Indian Express

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