Outcomes and prognosis

Outcomes and prognosis features

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  How long have I got, doc?

  Can people with HIV really live as long as anyone else? Gus Cairns investigates ...

  From:  HIV treatment update

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  Why we won’t die of AIDS

  A study in France has found that, whatever older people with HIV die of, it probably won’t be AIDS. In recent years one of the increasingly hot topics...

  From:  HIV treatment update

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  How does HIV make us sick?

  Nearly 30 years after the first documented cases of AIDS, we still don’t know exactly how HIV destroys the immune system. But inflammation – sustained immune activation...

  From:  HIV treatment update

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  Adherence and long-term treatment success

  Taking your HIV medication correctly (the technical term for this is adherence) is the single most important thing you can do to make sure your HIV treatment...

  From:  HIV treatment update

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  A ‘functional cure’?

  Examining the excitement over a bone marrow transplant that ‘eradicated’ HIV, by Edwin J Bernard. ...

  From:  HIV treatment update

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  Can we create ‘elite controllers’?

  Is combination immunotherapy the future? ask Edwin J Bernard and Derek Thaczuk ...

  From:  HIV treatment update

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  Defining, and then watching for, treatment failure

  A review of various clinical, immunological and virological definitions of antiretroviral treatment failure in resource-limited settings....

  From:  HIV & AIDS treatment in practice

Outcomes and prognosis in your own words

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  Life on HIV treatment – a personal perspective

  I’ve been taking HIV treatment for ten years – that's longer than the average life expectancy of someone with HIV when I was diagnosed back in 1991. I’ve...

  From:In your own words

Outcomes and prognosis news from aidsmap

• Continuing cotrimoxazole in children on ART reduces the risk of hospitalisation

  Children on ART for more than two years who continued taking daily cotrimoxazole had significantly fewer hospitalisations for malaria as well as for non-malarial infections (notably pneumonia, sepsis and meningitis), compared to children who stopped this treatment, researchers from Uganda ...

  06 March 2013 | Carole Leach-Lemens

• In resource-rich countries, migrants have a higher risk of progressing to AIDS in the first year of HIV therapy

  Rates of AIDS-defining illnesses in the first year of antiretroviral therapy are significantly higher among migrant than non-migrant populations in resource-rich countries, investigators report in the online edition of AIDS. The difference was mainly driven by higher rates of tuberculosis ...

  01 March 2013 | Michael Carter

• Study shows value of hepatitis C therapy for HIV co-infected patients with compensated cirrhosis

  Spanish research published in the online edition of Clinical Infectious Diseases shows the benefits of successful hepatitis C therapy for people co-infected with HIV who have compensated liver cirrhosis. Achievement of a sustained virological response (SVR) was associated with lower ...

  28 February 2013 | Michael Carter

• Triple trouble: infection with hepatitis B increases risk of death for people with HIV and hepatitis C co-infection

  Infection with hepatitis B virus (HBV) is associated with a poorer prognosis for people living with HIV who are co-infected with hepatitis C virus (HCV), Spanish investigators report in a study published in the online edition of AIDS. After taking ...

  19 February 2013 | Michael Carter

• Tenofovir impairs enzyme that stops cells ageing

  A team of Australian researchers has found that tenofovir and, to a lesser extent, other drugs from the nucleoside/nucleotide reverse transcriptase inhibitor (NRTI) class, impairs an enzyme that slows down or stops ageing processes in immune cells in the test ...

  31 January 2013 | Gus Cairns

• Spanish research shows that liver stiffness can predict outcomes in people co-infected with HIV and hepatitis C

  Liver stiffness is a strong predictor of hepatic complications and all-cause mortality in people co-infected with HIV and hepatitis C virus (HCV), Spanish investigators report in the online edition of AIDS. Liver stiffness was assessed using an ultrasound-based technique ...

  30 January 2013 | Michael Carter

• Mortality rates continue to fall in the Swiss HIV cohort

  Mortality in people with HIV is continuing to fall, Swiss investigators report in HIV Medicine. The mortality rate in 2010 was a little over 1% and the majority of deaths were due to non-AIDS-related causes, many of which ...

  25 January 2013 | Michael Carter

• Australian researchers project that many HIV-positive people will run out of treatment options

  Running out of antiretroviral treatment options may severely curtail the life expectancy of people with HIV in resource-rich countries, according to Australian research published in the online edition of AIDS. The research expands upon a study ...

  22 January 2013 | Michael Carter

• Prevalence of drug-resistant HIV has fallen dramatically among antiretroviral-experienced patients in Western Europe

  There has been a significant fall in the proportion of HIV-positive people in Western Europe with experience of HIV treatment who have resistance to antiretroviral drugs, investigators report in the online edition of the Journal of ...

  22 January 2013 | Michael Carter

• Large study shows the hepatic safety of HIV therapy

  Results from a large study published in the online edition of Clinical Infectious Diseases provide reassurance about the hepatic safety of antiretroviral drugs. Investigators from the D:A:D study into the side-effects of HIV treatment found that liver-related deaths caused by ...

  22 January 2013 | Michael Carter

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Outcomes and prognosis news selected from other sources

• Men in same-sex marriages are living longer, study says

  Men in same-sex marriages are living longer, according to Danish researchers, but mortality rates among married lesbians have begun to rise after a long period of decline.

  13 March 2013 | Los Angeles Times

• Anti-HIV drug effort in South Africa yields dramatic results

  An intensive campaign to combat HIV/AIDS with costly antiretroviral drugs in rural South Africa has increased life expectancy by more than 11 years and significantly reduced the risk of infection for healthy individuals, according to new research.

  22 February 2013 | Los Angeles Times

• Texas: Food availability linked with poor outcomes for HIV-positive children

  An HIV-positive child whose family does not have enough good food available is more likely to have a poor clinical outcome, researchers reported. They found that children who did not always have enough to eat had lower CD4 counts as well as higher chances of incomplete viral suppression.

  12 February 2013 | Baylor College of Medicine press release

• Minorities With HIV Fare Better With Culturally Competent Doctors

  The health outcomes of minorities receiving HIV care is generally dependent on the cultural competency of their physicians.

  08 February 2013 | AIDSMeds

• Multiple factors affect HIV prognosis, study shows

  In a major advancement for the field of HIV treatment, a new study has identified a more accurate method of suggesting prognosis for HIV patients. The new method, called the Veterans Aging Cohort Study index, takes into account factors such as hemoglobin level, platelet count and comorbidity.

  05 February 2013 | Yale Daily News

• HIV patients in care lose more years of life to smoking than to HIV infection

  Among HIV patients receiving well-organized care with free access to antiretroviral therapy, those who smoke lose more years of life to smoking than to HIV, according to a Danish study published in Clinical Infectious Diseases and available online.

  21 December 2012 | EurekAlert

• AIDS drug roll-out boosts South African life expectancy

  South Africa has achieved a "stunning" increase in life expectancy in the last three years due to a government push to roll out antiretroviral drugs (ARVs) to people with HIV/AIDS, researchers said on Thursday.

  01 December 2012 | Reuters

• Jamaica slashes HIV/AIDS deaths

  JAMAICA has seen a significant reduction of up to 50 per cent in the number of people who have died from HIV/AIDS since the introduction of public access to anti-retroviral (ARV) drugs in 2004.

  26 November 2012 | Jamaica Observer

• HIV Deaths Declining for Most, But Not All, Americans

  HIV death rates in the United States declined for most groups of people between 1993 and 2007, according to a large new study.

  09 October 2012 | U.S. News & World Report

• "Premature Aging" and HIV: Dispelling Myths and Calculating Risk

  Here's the bottom line on "accelerated aging" among people with HIV: It's probably not as bad as you think.

  25 September 2012 | The Body

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