Nystatin (Nystan / Nystaform / Tinaderm-M)

Nystatin (Nystan / Nystaform / Tinaderm-M) is an anti-fungal agent approved for the treatment of candidiasis. It can be also be used to prevent candidiasis in patients with HIV, particularly when they have low CD4 cell counts.1

Nystatin is available as tablets, a mouthwash and in pastilles, creams and ointments. Side-effects can include nausea, vomiting and diarrhoea at high doses.

In people with HIV, nystatin treatment is often unsuccessful, and relapses of candidiasis are common.2

Nystatin is manufactured by Bristol-Myers Squibb.

References

  1. MacPhail LA et al. Prophylaxis with nystatin pastilles for HIV-associated oral candidiasis. J Acquir Immune Defic Syndr Hum Retrovirol 12: 470-476, 1996
  2. Pons VG et al. Oropharyngeal candidiasis in patients with AIDS: randomized comparison of fluconazole versus nystatin oral suspensions. Clin Infect Dis 24: 1204-1207, 1997

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