Cuba

News from aidsmap

• Six existing drug classes now being tested as microbicides

  Microbicides
  Gus Cairns | 23 May 2010

  A number of presentations at the 2010 International Microbicides Conference in Pittsburgh concerned microbicide research using established classes of HIV drugs that have not been used as microbicides before. Trial of ...

• Early tests of maraviroc as microbicide produce less activity than expected

  Transmission and prevention
  Gus Cairns | 23 July 2009

  Preclinical ex-vivo tests of the entry inhibitor drug maraviroc as a possible microbicide have found that the drug only produced a moderate protective effect against HIV - a 50-60% inhibition ...

• Study shows potential for using dried blood spots for HIV viral load testing

  HIV treatment
  Theo Smart | 08 April 2009

  Dried blood spots can be used to measure HIV viral load, using the Abbott RealTime HIV-1 assay, although they tend to produce somewhat higher values than viral load tests in ...

• Microbicides 2008: Cellulose sulphate has unexpected tissue toxicity

  Transmission and prevention
  Gus Cairns | 03 March 2008

  Investigations into the candidate microbicide cellulose sulphate (Ushercell) using the substance on vaginal tissue samples have revealed that it causes loss of tissue integrity by destroying proteins that bind cells ...

• Microbicides 2008: First hint of efficacy in rectal microbicide trial, thanks to new biopsy assay

  Transmission and prevention
  Gus Cairns | 25 February 2008

  Preliminary, still blinded data presented to the 2008 Microbicides Conference in Delhi today offered a strong hint that a rectal microbicide gel containing a non-nucleoside HIV drug may prove to ...

• CROI: Recent infection responsible for one-quarter of HIV transmission amongst London's gay men

  Transmission and prevention
  Edwin J. Bernard | 22 February 2008

  Recent HIV infection appears to be responsible for at least a quarter of onward HIV transmission according to two studies presented to the recent Fifteenth Conference on Retroviruses and Opportunistic ...

• ICAAC: Dapivirine safe and tolerable as potential vaginal microbicide; displays potential in combination with other agents

  Microbicides
  Derek Thaczuk | 20 September 2007

  The NNRTI dapivirine has demonstrated clinical safety and tolerability when tested in HIV-negative women as a potential vaginal microbicide; dapivirine, tenofovir and another investigational product (L-860,167) have shown in-vitro anti-HIV ...

• Green tea has anti-HIV effect in test tube

  How HIV works
  Keith Alcorn | 28 March 2007

  An ingredient in green tea may reduce HIV binding to human CD4 cells by approximately 40% within an hour of drinking two to three cups of green tea, according to ...