New and experimental HIV treatments: latest news

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  • Orphan Drug Designation for CytoDyn's PRO 140 Declined by the FDA

    Cytodyn has announced that its application for Orphan Drug Designation (ODD) for PRO 140 was not granted by the Office of Orphan Products Development of the U.S. Food and Drug Administration (FDA) because PRO 140 appears to have the potential to treat more than just the subset of multi-drug resistant HIV patients for which the designation was requested.

    18 April 2017 | Cytodyn press release
  • New antibody therapy “profoundly” successful at reducing inflammation from HIV

    In a very small study of people living with HIV, a one-time antibody treatment significantly reduced the type of inflammation that can lead to heart attacks and other cardiovascular problems.

    09 March 2017 | BETA blog
  • Clinical Commissioning Policy: Tenofovir Alafenamide for treatment of HIV 1 in adults and adolescents

    TAF containing products can be made available to patients who have defined renal or bone problems or who have medical reasons why they cannot take other HIV drugs.

    06 March 2017 | NHS England
  • New nano approach could cut dose of leading HIV treatment in half

    Successful results of a University of Liverpool-led trial that utilised nanotechnology to improve drug therapies for HIV patients has been presented at the Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle, a leading annual conference of HIV research, clinical practice and progress.

    21 February 2017 | University of Liverpool press release
  • Merck's lead HIV play hits the mark in first phase 3 challenge

    Merck has taken a big step toward getting its lead HIV candidate doravirine to market, setting up a showdown with Johnson & Johnson's big-selling Prezista.

    19 February 2017 | FierceBiotech
  • URMC drug extends effectiveness of HIV therapy

    A drug developed at the University of Rochester Medical Center extends the effectiveness of multiple HIV therapies by unleashing a cell's own protective machinery on the virus. The finding, published today in the Journal of Clinical Investigation, is an important step towards the creation of long-acting HIV drugs that could be administered once or twice per year, in contrast to current HIV treatments that must be taken daily.

    31 January 2017 | EurekAlert (press release)
  • SA can save billions with new HIV drug combination

    The ADVANCE study will evaluate an HIV treatment regimen including two newer and cheaper drugs: dolutegravir (DTG) and tenofovir alafenamide (TAF).

    17 January 2017 | Health24
  • GlaxoSmithKline’s New Drug Challenges HIV Treatment Orthodoxy

    GlaxoSmithKline PLC’s ViiV Healthcare announced positive phase-three trial results for its new HIV drug in a dual-drug regimen, supporting the company’s audacious bet that it can shift the treatment orthodoxy away from three-drug combinations.

    20 December 2016 | Wall Street Journal
  • Positive Results From First Phase III Studies of Investigational Two-Drug HIV Treatment Regimen

    Janssen Sciences Ireland UC (Janssen) today announced that two Phase III studies to evaluate the safety and efficacy of switching virologically suppressed patients from a three or four drug (integrase inhibitor-, non-nucleoside reverse transcriptase inhibitor-, or boosted protease inhibitor-based) antiretroviral regimen to the two drug regimen of rilpivirine (Janssen) and dolutegravir (ViiV Healthcare) met the primary endpoint of non inferiority at week 48.

    20 December 2016 | Janssen press release
  • Charlie Sheen Achieves Undetectable Viral Load With Weekly Injectable HIV Treatment

    Actor Charlie Sheen revealed this month that he has achieved an undetectable viral load by taking PRO 140, an injectable HIV drug that's currently being studied. Sheen started taking PRO 140 as a study participant in a phase-3 clinical trial that is looking into the drug's safety and effectiveness in humans.

    08 December 2016 | The Body
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.