As many as 50% of those on combination antiretroviral therapy (cART) suffer from mild to moderate cognitive dysfunction. Antiretroviral medications themselves may be partly to blame for such neurocognitive problems, suggests a recent review of previous studies. But the authors of this review do not recommend that antiretroviral treatment be stopped.
3 hours ago | The Body Pro
A new study has found that low- and high-frequency hearing is poorer in adults with the human immunodeficiency virus, compared with adults who do not have the disease. Although unexpected, similar hearing loss has previously been observed to be more likely in adults with diabetes mellitus. "It is possible that both HIV infection and diabetes, being systemic diseases, could affect the neural function of the cochlea," the authors suggest.
29 December 2014 | Medical News Today
“Hepatitis C infection has serious long-term side effects, such as damage to the liver, but our research indicates that it does not affect the brain,” said lead author David Clifford, MD, of Washington University.
15 December 2014 | Washington University press release
The type of immune cell called macrophages, which have been proposed as a 'sanctuary site' of HIV in the brain and other organs, and as a possible cause of HIV-related brain impairment, don't live long enough to serve as reservoirs of HIV, a study in PLoS Pathogens finds.
04 November 2014 | EATG
HIV RNA remained detectable at low levels in cerebrospinal fluid (CSF) of almost 20% of patients who had HIV RNA levels below 40 copies/mL for up to 10 years of antiretroviral therapy (ART). The investigators believe their finding indicates that the central nervous system (CNS) can be an HIV reservoir during suppressive ART.
28 October 2014 | International AIDS Society
People with HIV and AIDS are living longer than was ever expected before the development of highly active antiretroviral therapies in the 1990s. Palm Springs, a Coachella Valley desert city 100 miles east of Los Angeles, has become a hub for older infected residents well into their 60s and 70s. Yet even as many live longer, there is a broad segment of HIV patients who are aging physically and cognitively faster than the rest of the population.
22 September 2014 | Newsweek
Although HIV dos not infect nerve cells, researchers strongly suspect that, once activated in the brain and the spinal cord, immune cells keep up a chronic inflammation level which then results in the destruction of nerve cells.
05 September 2014 | EATG
A medication commonly used to treat HIV appears to double the risk that patients will develop suicidal thoughts or take their lives, new research contends. The finding concerns the anti-HIV drug efavirenz, which is marketed as Sustiva.
02 July 2014 | Web MD
Treatment with HIV protease inhibitors (PIs) heightened chances of cerebral small-vessel disease (CSVD) in a group of US adults. And mild CSVD raised chances of HIV-associated neurocognitive disorder (HAND).
30 May 2014 | International AIDS Society
In an interview with The Telegraph, the World Dementia Envoy said any promising drugs should be given to “large populations” in order to speed the search for a breakthrough - as happened decades ago in the battle against HIV.
24 March 2014 | Daily Telegraph