Neurological and cognitive problems: latest news

Neurological and cognitive problems resources

  • Neuropathy - nerve pain

    Neuropathy is damage to the nerves. Nerves transmit signals within the brain and spinal cord (the central nervous system or CNS), and extend from the...

    From: Factsheets

    Information level Level 2
  • Dementia

    Dementia is the loss of the ability to think, remember and work things out. It usually affects older people. But, HIV can damage the brain...

    From: Factsheets

    Information level Level 2
  • Peripheral neuropathy

    Neuropathy refers to any type of nerve damage or injury. Neuropathy is common in people with HIV and AIDS and may be related to...

    From: HIV treatments directory

    Information level Level 4
  • Neuropathy

    Neuropathy means damage to the nerves. The nervous system consists of the central nervous system (CNS), which is comprised of the brain and the spinal...

    From: HIV treatments directory

    Information level Level 4

Neurological and cognitive problems features

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  • Predictors of HIV-related peripheral neuropathy in the modern era

    Researchers at major clinical centres in the U.S. have collaborated to study potential causes of peripheral neuropathy (PN) among HIV-positive people in the modern era. They recruited about 500 people who were free from PN and monitored them for an average of two years, performing extensive assessments. Taking into account many issues, statistical analysis found that there were several factors associated with an increased risk for PN.

    01 April 2015 | CATIE
  • HIV can spread early, evolve in patients' brains

    HIV can genetically evolve and independently replicate in patients' brains early in the illness process, an analysis of cerebral spinal fluid has found. Prompt diagnosis and treatment with antiretroviral therapy should reduce the risk that the virus could find refuge and cause damage in the brain, where some medications are less effective -- potentially enabling it to re-emerge, even after it is suppressed in the periphery, say researchers.

    27 March 2015 | Eurekalert Inf Dis
  • Researchers identify key mechanisms underlying HIV-associated cognitive disorders

    New findings, published today by researchers at the University of California, San Diego School of Medicine, open the door to the development of new therapies to block or decrease cognitive decline due to HIV-associated neurocognitive disorders, estimated to affect 10 to 50 percent of aging HIV sufferers to some degree.

    04 February 2015 | Medical Xpress
  • Researchers identify key mechanisms underlying HIV-associated cognitive disorders

    New findings, published today by researchers at the University of California, San Diego School of Medicine, open the door to the development of new therapies to block or decrease cognitive decline due to HIV-associated neurocognitive disorders, estimated to affect 10 to 50 percent of aging HIV sufferers to some degree.

    04 February 2015 | Eurekalert Medicine & Health
  • Antiretroviral Neurotoxicity May Cause Cognitive Problems

    As many as 50% of those on combination antiretroviral therapy (cART) suffer from mild to moderate cognitive dysfunction. Antiretroviral medications themselves may be partly to blame for such neurocognitive problems, suggests a recent review of previous studies. But the authors of this review do not recommend that antiretroviral treatment be stopped.

    28 January 2015 | The Body Pro
  • Could HIV make hearing worse?

    A new study has found that low- and high-frequency hearing is poorer in adults with the human immunodeficiency virus, compared with adults who do not have the disease. Although unexpected, similar hearing loss has previously been observed to be more likely in adults with diabetes mellitus. "It is possible that both HIV infection and diabetes, being systemic diseases, could affect the neural function of the cochlea," the authors suggest.

    29 December 2014 | Medical News Today
  • Hepatitis C ruled out as cause of mental impairment in HIV patients

    “Hepatitis C infection has serious long-term side effects, such as damage to the liver, but our research indicates that it does not affect the brain,” said lead author David Clifford, MD, of Washington University.

    15 December 2014 | Washington University press release
  • Immune cells proposed as HIV hideout don't last in primate model

    The type of immune cell called macrophages, which have been proposed as a 'sanctuary site' of HIV in the brain and other organs, and as a possible cause of HIV-related brain impairment, don't live long enough to serve as reservoirs of HIV, a study in PLoS Pathogens finds.

    04 November 2014 | EATG
  • HIV RNA lingers in CSF through up to 10 years of suppressive ART

    HIV RNA remained detectable at low levels in cerebrospinal fluid (CSF) of almost 20% of patients who had HIV RNA levels below 40 copies/mL for up to 10 years of antiretroviral therapy (ART). The investigators believe their finding indicates that the central nervous system (CNS) can be an HIV reservoir during suppressive ART.

    28 October 2014 | International AIDS Society
  • The First HIV/AIDS Generation Reaches Retirement Age

    People with HIV and AIDS are living longer than was ever expected before the development of highly active antiretroviral therapies in the 1990s. Palm Springs, a Coachella Valley desert city 100 miles east of Los Angeles, has become a hub for older infected residents well into their 60s and 70s. Yet even as many live longer, there is a broad segment of HIV patients who are aging physically and cognitively faster than the rest of the population.

    22 September 2014 | Newsweek
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