Neurological and cognitive problems

Neurological and cognitive problems features

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  Are we thinking clearly about brain impairment?

  For the last three years the UK’s HIV doctors’ and patients’ organisations - the British HIV Association (BHIVA) and the UK Community Advisory Board (UKCAB) - have collaborated...

  From:HIV treatment update

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  Scattered pictures – brain impairment and HIV

  Gus Cairns and Theo Smart investigate HIV-related brain impairment, memory loss and dementia ...

  From:HIV treatment update

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  Screening for HIV dementia

  Cli nical review of how to diagnose HIV dementia and other cognitive disorders in adults with HIV infection in resource-limited settings, with discussion of treatment...

  From:HIV & AIDS treatment in practice

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  Neuro AIDS

  Clinical review of the neurological disorders that can occur in HIV in resource-limited settings, and their prevalence and prognosis....

  From:HIV & AIDS treatment in practice

Neurological and cognitive problems news from aidsmap

• Cognitive function improves through the first year of HIV therapy

  Cognitive function continues to improve up to one year after starting antiretroviral therapy, according to the results of a small international study published in HIV Medicine. The investigators monitored changes in cognitive function six and twelve months after patients started ...

  29 March 2012 | Michael Carter

• HIV brain impairment: who gets it, and why?

  A number of papers at the 19th Conference on Retroviruses and Opportunistic Infections presented advances in research on HIV-related brain impairment and neurocognitive problems. A couple of problems have dogged research into HIV-related brain impairment. One is how to differentiate ...

  12 March 2012 | Gus Cairns

• Fat accumulation linked to cognitive impairment in patients with HIV

  Central fat accumulation is associated with an increased risk of neurocognitive impairment for HIV-positive patients, according to a study published in the February edition of Neurology. Overall 40% of patients in the study were diagnosed with impairment and increased waist circumference ...

  24 February 2012 | Michael Carter

• Hepatitis C doesn't affect cognitive function of women, but some evidence HIV does

  Infection with hepatitis C does not affect the cognitive performance of women with or at risk of HIV, according to data from the Women’s Interagency HIV Study (WIHS) published in the online edition of the Journal of Acquired ...

  08 December 2011 | Michael Carter

• How common is neurocognitive impairment in people with HIV? It depends who you compare them with

  How much more common is brain impairment and dementia in people with HIV than in the general population? A study presented at the 13th European AIDS Conference in Belgrade today showed that the answer could vary from 'no ...

  13 October 2011 | Gus Cairns

• Cognitive impairment still common but ART reduces risk

  Cognitive impairment remains common amongst people with HIV and is linked to more severe immune deficiency and absence of treatment, researchers reported at the International AIDS Society Conference (IAS 2011) this week in Rome. However, antiretroviral drugs that penetrate ...

  20 July 2011 | Liz Highleyman

• Brain impairment in people with HIV may not be as common as we thought

  Two studies presented at the17th British HIV Association (BHIVA) conference last week suggest that the proportion of people who have subtle brain impairment due to HIV may not be as high as previously thought, and may in fact be ...

  11 April 2011 | Gus Cairns

• Neuropathy still common in patients with HIV, older age a risk factor

  Peripheral neuropathy remains common in patients with HIV, US investigators report in the online edition of AIDS. Rates of the disease and its symptoms were monitored in over 2000 patients who started HIV therapy between 2000 and 2007. ...

  14 March 2011 | Michael Carter

• European Medicines Agency: d4T to be used only in last resort

  The European Medicines Agency has issued new guidance on the use of d4T (stavudine, Zerit), saying that the drug should be used only when no other alternative option exists, due to its toxicity. The agency’s Committee for Medicinal Products ...

  21 February 2011 | Keith Alcorn

• Increase in stroke among HIV-positive patients in US

  The proportion of US patients hospitalised because of stroke who are HIV-positive has increased significantly in recent years, investigators report in Neurology. This was at a time when stroke hospitalisations in the general US population were falling. “There was ...

  19 January 2011 | Michael Carter

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Neurological and cognitive problems news selected from other sources

• Pfizer Says Lyrica Fails in Diabetes Trial, Halts HIV Study

  Pfizer's Lyrica, approved for use in fibromyalgia, didn’t work to control painful nerve damage from diabetes in one study, and the company halted a second trial in nerve-damaged HIV patients.

  04 May 2012 | Bloomberg

• Why it's time to say goodbye to stavudine...everywhere

  Concerns about a proposed comparative trial of 40mg and 20mg (low-dose) stavudine in South Africa.

  16 April 2012 | South African Journal of HIV Medicine

• Can I Get A Witness! Authentic Voices Tell the Story of Neuropathy

  Authors, scientists, doctors, journalists and bloggers can write about neuropathy until they're blue in the face but there's no substitute for hearing people tell their own stories. This post is therefore given over to some of the men and women with both HIV and Neuropathy who have opened their hearts on forums and in blogs across the Net. There are many, many more!

  12 April 2012 | The Body

• Tenofovir does not penetrate CNS well in 183-person US study

  Tenofovir concentrations in cerebrospinal fluid are only 6% of blood plasma concentrations.

  29 March 2012 | International AIDS Society

• Dementia is a national crisis like HIV and cancer, says David Cameron

  Britain is facing a “national crisis” of dementia on a similar scale to the high rates of HIV and cancer in previous decades, David Cameron will warn today.

  26 March 2012 | Daily Telegraph

• CHARTER Study: Asymptomatic Cognitive Problems "Harbinger" for Future Neurologic Decline

  Numerous studies have noted increasing rates of neurological disorders in people living with HIV, but many of the cases included in these findings involve patients with cognition problems that don’t affect daily functioning—data often dismissed as being statistical artifacts or meaningless measurements.

  08 March 2012 | AIDSMeds

• NIH-funded study defines treatment window for HIV+ children infected at birth

  HIV-positive children older than 1 year who were treated after showing moderate HIV-related symptoms did not experience greater cognitive or behavior problems compared to peers treated when signs of their infection were still mild, according to a study funded by the National Institutes of Health.

  07 March 2012 | Eurekalert Inf Dis

• NeurogesX Fails to Win U.S. FDA Panel Backing for Patch to Treat HIV Pain

  NeurogesX Inc. (NGSX), a specialty drugmaker that has never reported an annual profit, failed to win the backing of a US advisory panel for its patch to relieve pain nerve damage commonly associated with HIV.

  09 February 2012 | Bloomberg

• NeurogesX Patch for HIV Pain Might Be Ineffective, FDA Staff Report Says

  A pain patch from NeurogesX Inc., a specialty drugmaker that has never reported an annual profit, may not relieve pain related to nerve damage commonly associated with HIV, U.S. regulators said.

  07 February 2012 | Bloomberg

• Memory loss can begin from age 45, scientists say

  Mental dexterity and brain power deteriorates earlier than thought, according to study of 7,000 civil servants.

  06 January 2012 | The Guardian

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