Microbicides: latest news

Microbicides resources

  • Microbicides

    Microbicides are any substances which protect people against infection by microbes, such as viruses or bacteria, on contact with those microbes....

    From: Preventing HIV

    Information level Level 4
  • Microbicides

    A microbicide is a topical agent that, when applied to a mucosal surface, serves as a barrier to infection. Microbicides can come in the form of...

    From: HIV transmission & testing

    Information level Level 4

Microbicides features

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  • Women’s bacteria thwarted attempt at anti-HIV vaginal gel

    Creating new HIV prevention tools for women has proven frustratingly slow and researchers have found another hurdle: bacteria in the reproductive tract.

    02 June 2017 | STAT
  • IPM Advances Three-month HIV Prevention and Contraception Ring to Clinical Trial

    The three-month vaginal ring is designed to slowly — and simultaneously — release the antiretroviral drug dapivirine to prevent HIV and the contraceptive hormone levonorgestrel. The primary goal of the study, known as MTN-030/IPM 041, is to assess the ring’s safety and pharmacokinetics (how the body processes the two drugs). Results of the trial, including the product’s acceptability to women and their willingness to use it in the future, will inform next steps for the ring’s formulation and future trial designs.

    03 May 2017 | International Partnership for Microbicides
  • MTN begins first trial of new dapivirine ring with both anti-HIV drug and contraceptive

    Researchers hoping for a single product to protect against both HIV and unintended pregnancy took an important step toward realizing their goal with the start of a trial of a vaginal ring containing the antiretroviral drug dapivirine and a hormonal contraceptive. A dapivirine-only ring that women use a month at a time was safe and helped prevent HIV in two large trials. The new ring adds levonorgestrel and could be used for three months.

    03 May 2017 | Eurekalert Medicine & Health
  • Vaginal Ring Form of PrEP Does Not Reduce Contraceptive Effectiveness

    The antiretroviral (ARV)-containing vaginal ring form of pre-exposure prophylaxis (PrEP) that reduced HIV risk in a major trial does not lower the effectiveness of hormonal birth control. This finding assuages concerns raised by previous research that the non-nucleoside reverse transcriptase inhibitor (NNRTI) class of ARVs has been associated with a lowered effectiveness of some hormonal contraceptives.

    16 February 2017 | Poz
  • IPM's dapivirine ring may offer significant HIV protection when used consistently

    New data analyses announced at the AIDS 2016 conference today provide additional evidence suggesting that the monthly dapivirine vaginal ring developed by the nonprofit International Partnership for Microbicides (IPM) provides significant protection against HIV infection in women when used consistently. The new data were released as two open-label studies of the ring begin and as IPM pursues regulatory approvals for the product for its use in developing countries.

    18 July 2016 | International Partnership for Microbicides
  • Treatment Action Group: Pipeline Report 2016

    Drugs, Diagnostics, Vaccines, Preventive Technologies, Research Toward a Cure, and Immune-Based and Gene Therapies in Development.

    15 July 2016 | Treatment Action Group
  • Five Exciting HIV Prevention Studies We’re Paying Attention To

    What’s on the horizon of HIV prevention? Here are five clinical trials to pay attention to, if you’re interested in what the next big breakthrough in the HIV prevention field may be.

    30 June 2016 | BETA blog
  • Can a gel to prevent HIV be applied as a lube?

    Rectal microbicide gels, applied either daily or before and after sex, are currently being investigated as an option for HIV pre-exposure prophylaxis (PrEP). Given that many people who have anal lready use lube, one hope is for an HIV-prevention product that people could essentially use in place of a lube. But can gels provide enough coverage across rectal tissue if people don’t use an applicator?

    18 March 2016 | BETA blog
  • NIAID to Fund Further Study of Dapivirine Vaginal Ring for HIV Prevention

    The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), announced today that it would move forward with an open-label extension study of an HIV prevention tool for women: a silicone ring that continuously releases the experimental antiretroviral drug dapivirine in the vagina. The new study builds on recently announced findings from the ASPIRE trial which found that the dapivirine ring safely provided a modest level of protection against HIV infection in sub-Saharan African women.

    14 March 2016 | National Institute of Allergy and Infectious Diseases
  • Vaginal ring for HIV prevention: a few details would have elevated good coverage to great

    Analysis of BuzzFeed's coverage of vaginal ring studies.

    01 March 2016 | Health News Review
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap

This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.