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  • Seroconversion

    I was given my diagnosis over the telephone after spending four days in hospital with meningitis. I now realise it wasn’t meningitis, it was an...

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  • Detectable HIV Despite Treatment? Clonal Expansion Could Be The Culprit

    In a study of people with a low but detectable viral load despite adherence to treatment, infected cells were apparently cloning themselves.

    14 March 2019 | Poz
  • HIV-Related Immune Activation May Predict Weight Gain and Exacerbate Complications, Especially in Women

    HIV can cause persistent immune activation that contributes to an increased risk of complications such as heart disease and certain cancers. New NIAID-supported research presented today [March 6] at the Conference on Retroviruses and Opportunistic Infections in Seattle sheds light on the relationship between immune activation and weight gain.

    11 March 2019 | HIV.gov
  • Has a second person with HIV been cured?

    “This is a big deal,” says Sharon Lewin, who heads the Peter Doherty Institute for Infection and Immunity in Melbourne, Australia. “It tells us that Timothy Brown wasn’t a one-off.” Although the interventions that the two patients received could only be used on a tiny fraction of the 37 million HIV-infected people worldwide, their stories point to cure strategies that could be more widely applicable.

    06 March 2019 | Science Magazine
  • Using anti-cancer immunotherapy to fight HIV

    Researchers at the University of Montreal Hospital Research Centre (CRCHUM) have shown that immunotherapy treatments against cancer could reduce the amount of virus that persists in people on triple therapy. In a study published in the journal Nature Communications, they show, in the cells of people living with HIV, how these therapies reveal the virus - until now hidden in the hollows of infected cells - to the immune system.

    20 February 2019 | Eurekalert Medicine & Health
  • Insufficient food linked to inflammation in HIV-positive women

    Past research with HIV-negative people suggests that food insecurity is associated with heightened levels of inflammation. Now, in a recent study, scientists at 10 major clinics across the U.S. have found that food insecurity was linked to an increased risk of elevated inflammation among HIV-positive women. The link between food insecurity and inflammation was present even in women whose viral loads were suppressed due to good adherence to ART.

    29 January 2019 | CATIE
  • HIV Establishes Reservoir Within Three Days in Monkeys

    Beginning six months of treatment within two days following infection prevented viral rebound in at least some animals in a recent study.

    01 January 2019 | Poz
  • Study Determines Why Patients With HIV Have Higher Rates of Cancer

    After investigating why patients with HIV have higher rates of cancer than the general population, researchers identified how T-cells move and multiply to invade other cells in these patients.

    17 December 2018 | American Journal of Managed Care
  • Needles in a haystack: the quest for bnAbs

    HIV induces antibody responses in infected individuals, but only a few of these individuals manage to produce antibodies that are capable of viral neutralization—and even fewer produce antibodies that can neutralize different strains of HIV.

    01 December 2018 | Nature
  • Virus detectives test whole-body scans in search of HIV’s hiding places

    To prevent the virus from rebounding after drug therapy, researchers must first map where it lurks in the body.

    23 October 2018 | Nature
  • PET Scans May Predict Who Gets Inflammatory Reaction to HIV Treatment Start

    The imaging method known as a PET scan may be able to predict who among those starting antiretroviral (ARV) treatment with an immune system highly damaged by HIV will develop HIV-associated immune reconstitution syndrome (IRIS).

    26 September 2018 | Poz
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