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  • Seroconversion

    I was given my diagnosis over the telephone after spending four days in hospital with meningitis. I now realise it wasn’t meningitis, it was an...

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  • First glimpse of how HIV swamps the gut's immune cells

    We've been given the first glimpse of HIV in attack mode in the gut, shedding light on how the virus hijacks immune cells, multiplies and spreads throughout the body. A team of biochemists have used electron tomography microscopes to capture the high-resolution, 3D images.

    31 January 2014 | New Scientist
  • Discovering where HIV persists in spite of treatment

    Recently discovered T memory stem cells may be long-term viral reservoir, potential targets for future treatment.

    13 January 2014 | Harvard Gazette
  • How HIV Destroys Immune Cells

    HIV leads to AIDS primarily because the virus destroys essential immune cells called CD4 T cells, but precisely how these cells are killed has not been clear. Two papers published simultaneously today (19 December) in Nature and Science reveal the molecular mechanisms that cause the death of most CD4 T cells in lymphoid tissues, the main reservoir for such cells, during infection.

    20 December 2013 | The Scientist
  • Rift widens over structure of HIV’s molecular anchor

    Studies of a potential vaccine target bolster claims that an earlier paper was flawed.

    05 November 2013 | Nature
  • Bursting HIV’s bubble

    HIV has a fatty outer membrane similar to that surrounding a living cell. This membrane probably acts like a balloon—in other words the pressure inside it is greater than the pressure outside it. That means it can be burst, which is what some scientists believe provides the driving force by which a virus injects its genetic material into a cell in order to infect it.

    18 October 2013 | The Economist
  • Gene discovery could lead to new types of HIV treatments

    Scientists have identified a gene which they say may have the ability to prevent HIV, the virus that causes AIDS, from spreading after it enters the body. In an early-stage study in the journal Nature, researchers said the gene, called MX2, appears to play a key role in how HIV is controlled in human cells.

    19 September 2013 | Reuters
  • Changes in Gut Bacteria May Promote Inflammation and HIV Disease Progression

    Changes in intestinal bacteria may contribute to disease progression and development of non-AIDS conditions in people with HIV, even those on effective antiretroviral therapy (ART), according to a report in the July 10, 2013, issue of Science Translational Medicine.

    25 July 2013 |
  • GHANA: Mold Toxins Tied to AIDS Epidemic

    A new study has examined the impact of aflatoxins on the AIDS epidemic in Africa. Aflatoxins are poisons produced by aspergillus fungi that can be found on damp grains, nuts, and beans, usually in hot humid climates. They have also been found to be immunosuppressive, possibly causing increased immunosuppression in HIV-positive individuals.

    24 July 2013 | CDC National Prevention Information Network
  • The immune system, HIV, and aging

    The purpose of this brief report is to outline current scientific knowledge regarding the immunologic connections between HIV and aging, and provide an introduction to some of the unresolved questions that are being addressed—or need to be addressed—by research.

    07 June 2013 | TAG
  • NIH scientists discover how HIV kills immune cells

    Untreated HIV infection destroys a person's immune system by killing infection-fighting cells, but precisely when and how HIV wreaks this destruction has been a mystery until now. New research by scientists at NIAID reveals how HIV triggers a signal telling an infected immune cell to die. This finding has implications for preserving the immune systems of HIV-infected individuals.

    07 June 2013 | Eurekalert Inf Dis
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