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How HIV causes disease: latest news

How HIV causes disease resources

  • CD4 cell counts

    CD4 cells (sometimes called T-cells, T-lymphocytes, or helper cells) are white blood cells that play an important role in the immune system. Your CD4 cell count gives...

    From: Factsheets

    Information level Level 2
  • Health issues

    If you are ‘HIV positive’ this means that you have a virus called HIV in your body. It doesn’t mean that you are ill, or that...

    From: Booklets

    Information level Level 2
  • HIV and the immune system

    The immune system is the body’s natural defence system. It’s a network of cells, tissues and organs inside the body.The immune system recognises and fights...

    From: The basics

    Information level Level 1
  • CD4 and viral load

    It’s important for all people with HIV to take regular blood tests. The two most important blood tests are for CD4 and viral load.A CD4...

    From: The basics

    Information level Level 1
  • The immune system and HIV

    A description of how the immune system works, its response to HIV, and factors affecting disease progression....

    From: HIV treatments directory

    Information level Level 4

How HIV causes disease features

How HIV causes disease news from aidsmap

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How HIV causes disease news selected from other sources

  • HIV entry mechanism into immune cell nucleus revealed

    How does HIV enter the nucleus of immune cells when it is bigger than the pores in its walls? New research shows it hijacks a protein to enlarge the pores.

    22 July 2016 | HIV / AIDS News From Medical News Today
  • New study reveals how HIV enters cell nucleus

    Scientists have solved a mystery that has long baffled HIV researchers: How does HIV manage to enter the nucleus of immune system cells? The discovery could lead to effective new drugs to treat HIV/AIDS.

    23 June 2016 | Science Daily
  • WHO confirms antiretroviral therapy reduces the risk of life-threatening HIV-related infections

    Adults and children with HIV who start antiretroviral therapy (ART) as early as possible reduce their risk of developing serious HIV-related infections, according to new findings published in the journal Clinical Infectious Diseases on 15 June 2016.

    22 June 2016 | World Health Organization
  • Men With HIV Age Faster According to DNA Methylation Study

    Infection with HIV may be associated with accelerated cellular aging, according to a new study in which researchers analyzed DNA methylation patterns of men with HIV infection. The study provides a possible explanation for why people with HIV who take antiretroviral medications often develop age-related conditions such as cardiovascular disease, hypertension, bone fractures, and renal failure years earlier than those who are uninfected.

    16 June 2016 | JAMA
  • HIV infection prematurely ages humans by an average of 5 years

    Thanks to combination antiretroviral therapy, many people with HIV can be expected to live decades after being infected. Yet doctors have observed that these patients often show signs of premature aging. Now a study published April 21 in Molecular Cell has applied a highly accurate biomarker to measure just how much HIV infection ages people at the biological level -- an average of almost 5 years.

    22 April 2016 | Eurekalert Inf Dis
  • New research explains why HIV is not cleared by the immune system

    Scientists have identified a human (host) protein that weakens the immune response to HIV and other viruses. The findings have important implications for improving HIV antiviral therapies, creating effective viral vaccines, and advance a new approach to treat cancer.

    15 April 2016 | Science Daily
  • What Is Chronic Inflammation and Why Is It Such a Big Deal for People With HIV?

    A primer on the harms of HIV-related chronic inflammation, what treatments are being researched and what you can do to reduce inflammation and improve your long-term health.

    06 April 2016 | Poz
  • How HIV infection increases the risk of tuberculosis

    A study published in PLOS Pathogens suggests that it is not a general weakening of the immune system by HIV that initially leads to loss of Mtb control, but rather that HIV is associated with a failure to prevent harmful immune responses. As HIV disease progresses, the weakening immune system's focus on antiviral responses leaves it largely defenseless against the Mtb pathogen.

    18 March 2016 | HIV / AIDS News From Medical News Today
  • Bacteria, viruses in gut linked to severity of HIV infection

    HIV infection also can lead to diseases affecting the intestines, with increased gastrointestinal (GI) inflammation, diarrhea and problems with nutrient absorption. The role of gut microbes in such issues is not completely understood, but now, in two studies led by researchers at Washington University School of Medicine in St. Louis, scientists have identified intestinal bacteria and viruses as possible sources of such inflammation and disease.

    11 March 2016 | HIV / AIDS News From Medical News Today
  • Infection with multiple HIV-1 variants leads to poorer clinical outcomes

    HIV-1 infection with multiple founder variants points to poorer clinical outcomes than infection with a single variant, according to a paper published today in Nature Medicine. In the study researchers analyzed large sample sets from two important HIV vaccine efficacy trials -- the Step HIV vaccine clinical trial (HVTN 502) and RV144, the landmark vaccine clinical trial conducted in Thailand -- to evaluate whether genetic characteristics of the founder viral populations could influence markers of clinical outcomes.

    01 September 2015 | Eurekalert Inf Dis
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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