Health monitoring in resource-limited settings

Health monitoring in resource-limited settings features

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  Strengthening labs and introducing new tools for increased case detection and earlier diagnosis of TB

  This edition looks at the relationship between strengthening of laboratory diagnostic capacity and intensified case finding for TB in people living with HIV...

  From:HIV & AIDS treatment in practice

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  South Africa is moving towards an AIDS-free generation, and improving survival in children living with HIV

  Reductions in vertical HIV transmission to infants and improvement in paediatric survival attributable to the scale of and quality improvement of prevention of parent-to-child transmission (PPTCT) and antiretroviral...

  From:HIV & AIDS treatment in practice

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  Cervical cancer in women with HIV

  Cervical cancer is one of the major causes of death and illness in women globally.Cervical cancer is...

  From:HIV & AIDS treatment in practice

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  Kidney disease in people with HIV: a clinical review (part one)

  First in a series on kidney disease in resource-limited settings. This edition covers the scale of the problem, diagnosing kidney disease and monitoring kidney function....

  From:HIV & AIDS treatment in practice

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  Monitoring

  Potential for use of dried blood spots for monitoring....

  From:HIV & AIDS treatment in practice

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  Clinical monitoring as effective as CD4 count and viral load for deciding when to switch to second-line ART in poor countries

  This issue reviews monitoring options for switching to second-line in resource-poor settings. ...

  From:HIV & AIDS treatment in practice

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  Cheap viral load test is urgently needed for resource-poor settings, say treatment advocates

  Review of evidence on the need for viral load testing to guide antiretroviral treatment switching in resource-limited settings....

  From:HIV & AIDS treatment in practice

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  Laboratory requirements for scaling up HIV treatment

  Review of how laboratory systems in resource-poor settings are scaling up to monitor HIV disease and antiretroviral treatment....

  From:HIV & AIDS treatment in practice

Health monitoring in resource-limited settings news from aidsmap

• Improved health, wish for normal life, main reason for loss to follow-up in Ugandan HIV patients

  Wanting to return to a ‘normal’ life after having experienced an improvement in health on HIV treatment was the key reason for loss to follow-up of three-quarters of patients who didn't return to a Kampala HIV clinic, according to ...

  17 April 2012 | Carole Leach-Lemens

• Treatment as prevention is starting to work in parts of Africa

  A longitudinal study from KwaZulu Natal province in South Africa is the first study from the global south to relate an increase in the proportion of adults on HIV treatment to a fall in HIV incidence, the 19th Conference on ...

  18 March 2012 | Gus Cairns

• When does viral load testing add value in sub-Saharan Africa?

  Routine viral load testing did not catch failure of first-line treatment earlier than discretionary viral load testing, but it did reduce the period on failing treatment by nearly a year in a study conducted in Zambia, Dr Mike Saag ...

  08 March 2012 | Keith Alcorn

• Second-line treatment failure most often due to poor adherence in low and middle-income countries

  Poor adherence rather than drug resistance appears more likely to be the cause of virological failure among patients on second-line ART in resource-poor settings, according to a systematic review and meta-analysis published in the advance online edition of AIDS. The cumulative ...

  24 February 2012 | Carole Leach-Lemens

• Rapid ‘combination’ test fails to detect many cases of acute HIV infection

  A rapid, point-of-care test, which aims to reduce the ‘window period’ through the detection of both antibodies and p24 antigen has poor performance in a clinical setting, researchers report in an article published online ahead of print by the ...

  06 January 2012 | Roger Pebody

• Treatment switches after CD4 count decline reduce risk of death by 75% in Zambia, Malawi

  Mortality was reduced by about 75% among adults experiencing immunological failure according to the World Health Organization (WHO) criteria who switched to a second-line regimen compared to those who remained on a failing regimen in two public sector ART programmes ...

  09 December 2011 | Carole Leach-Lemens

• Point-of-care CD4 test improves retention and treatment initiation in Mozambique

  The use of a point-of-care CD4 cell count test dramatically reduced the rate of loss to follow-up among patients diagnosed with HIV at clinics in Mozambique and doubled the number of patients who started treatment, according to findings from ...

  28 September 2011 | Keith Alcorn

• How best to deploy point-of-care CD4 cell testing in resource-limited settings?

  Widespread introduction of point-of-care (POC) CD4 cell tests that don’t require a laboratory technician but can be performed onsite by a nurse, providing results in less than an hour – while the patient waits) is expected in the ...

  19 July 2011 | Theo Smart

• Viral load monitoring of ART patients linked to lower death rate on treatment in southern Africa

  After three years on ART patients enrolled in four scale-up programmes with routine viral load monitoring in South Africa had a fifty percent lower death rate than patients in two public sector programmes in Malawi and Zambia where monitoring is ...

  14 July 2011 | Carole Leach-Lemens

• Treatment monitoring: no clear benefit to adding viral load to CD4 or clinical symptoms in Thailand and Africa

  Viral load is probably not essential for determining when to switch to second-line treatment in low- and middle-income settings, two large randomised trials conducted in Thailand and Cameroon have reported. Clinical monitoring alone, without any laboratory tests, did not ...

  01 March 2011 | Keith Alcorn

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Health monitoring in resource-limited settings news selected from other sources

• Predictive tool could cut HIV test costs

  A tool to monitor how HIV-positive patients respond to antiretroviral therapy (ART) could free up scarce personnel and laboratory resources in developing countries, according to an international team of researchers.

  08 May 2012 | SciDev Net

• UNITAID statement on World Malaria Day 2012 Investing in Diagnostics to Improve Treatment

  As the international community commemorates World Malaria Day this week, UNITAID is gearing up for its next round of agenda-setting investments in malaria: quality and innovative diagnostic technology.

  25 April 2012 | UNITAID

• Communications Engineers Join Fight Against AIDS In Africa Through Wireless Printer Program

  The Huffington Post reports on how communications engineers have developed a project in Mozambique that brings wireless printers equipped with cell phone technology to remote villages, in order to deliver HIV test results fast.

  11 April 2012 | Kaiser Daily Global Health Policy Report

• Origami paper device can test for HIV and malaria

  Chemistry professor Richard Crooks and chemistry graduate student Hong Liu developed an origami Paper Analytical Device, or oPAD, that chemically analyzes human bodily fluids and identifies different biomarkers that signal the presence of disease. The device works with folded paper to run complex tests using less surface area and costs under 10 cents.

  23 March 2012 | The Daily Texan

• Smartphones more accurate, faster, cheaper for disease surveillance

  Smartphones are showing promise in disease surveillance in the developing world. The Kenya Ministry of Health, along with researchers in Kenya for the Centers for Disease Control and Prevention, found that smartphone use was cheaper than traditional paper survey methods to gather disease information, after the initial set-up cost.

  13 March 2012 | Eurekalert Inf Dis

• Sensors To Test For Malaria And HIV Printed And Assembled For Less Than 10 Cents

  Inspired by the paper-folding art of origami, chemists at The University of Texas at Austin have developed a 3-D paper sensor that may be able to test for diseases such as malaria and HIV for less than 10 cents a pop.

  12 March 2012 | HIV / AIDS News From Medical News Today

• SWAZILAND: No money, no CD4 tests

  Swaziland is still short of lab reagents needed for CD4 count testing, which is used to initiate and monitor patients on antiretroviral treatment, and HIV-positive people are growing increasingly frustrated as the country enters its fourth month without a way to establish the strength of their immune system. 

  23 January 2012 | IRIN Plus News

• Uganda - Boost for people living with HIV in western Ugandan district

  People in Kabarole, western Uganda look set to see an improvement in HIV diagnosis, care and treatment due to the arrival of a new CD4 count machine.

  20 January 2012 | Key Correspondents

• Alere Pima CD4 test receives prequalification from the World Health Organization

  The World Health Organization (WHO) has prequalified the Alere Pima™ CD4 Test as part of an effort to increase access to rapid and accurate HIV/AIDS monitoring tools.  The Alere Pima™ CD4 Test is the first and only point-of-care diagnostic designed for the measurement of absolute CD4 counts to receive such recognition from the WHO.

  15 December 2011 | The Medical News

• Canadian team's portable device could ease HIV/AIDS monitoring

  Canadian researchers have invented a device that could make it easier, faster and cheaper to track the progression of HIV in patients living in the developing world.

  12 December 2011 | Vancouver Sun

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